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Homo sapiens (human) CALML3 antisense RNA 1 (CALML3-AS1) URS000075E62E_9606

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CALML3-AS1: CALML3-AS1 is a long non-coding RNA (lncRNA) that has been found to be highly expressed in cervical cancer (CC) samples [PMC8170088]. A recent study has shown that CALML3-AS1 plays a role in inhibiting papillary thyroid carcinoma (PTC) tumorigenesis by acting as a competing endogenous RNA (ceRNA) [PMC8966157]. It achieves this by acting as a sponge for miR-20a-5p, thereby regulating the expression of RBM38 [PMC8966157]. This study provides the first evidence of CALML3-AS1's involvement in PTC tumorigenesis and its ceRNA mechanism of action [PMC8966157]. The findings suggest that CALML3-AS1 may have potential as a therapeutic target for PTC treatment. Further research is needed to fully understand the molecular mechanisms underlying CALML3-AS1's role in cancer development and its potential clinical applications.

Genome locations

Gene Ontology annotations

Sequence

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UUUAUUUCCCUGCAGCUCUCAUCCCCUGCUCAUCCAAGCCUCCCUCCUUCCAGAUGAAUAGGAACAGGUUACAGCUGACCCAGUUUCACUCCCAGCUUCAGAAGAUGAAUCACGAUAUUUGAGUGCCUACUAGGUGCAGUGUCACUCUGGAAGCUGGGAACACAGUGGGACCGGCAAGCCACCCCCAGUCCUCGUGAGGUUAACUAGCAAGACAGCUAGUUUGCAGGGGCUGGAGAGACUUCUUCAUGAAGGAAUACAGGGACAGUCACAGGAGACAGGAGCACCAAGGGAUUCGGACAUGUGGCUGACACAGUCUUCUGGAGAGCCCCGGAUGGCAUCAGGGGGAAACCUGGCCUGAGACAGUGCCCUGAUGGACAAGGACAGGAAUACGGUCAUACCUCCUGCCCACUUGACCAACGACCAGGAUGAGAAGCCAACAGAUGAUGAAUAUGAAUUAAAGUUGGACAACUAGCAAGUUUAAAACUUGGACUGGGACCUAGAUCUUCCGAUUCCUACAGCUAGCCUCCCUUUCCAUCUUCUCUGUGGUCAUCACUAAUGCAGUUUUUGACCGUCUUGUCCAGAAGCUGCAAAACAGACAACAGAAGCCAGGACUGGCCCUGCCUUAGAUGGCUUUCAGUGCAGGAAAGUAUCAAGACAGUCUUGUUCGUAGCGUAUAUCUCUCUCCACCUUUUCUGCUAAGCACCUCAUGUAUGCAGCUGCCAAUGUAACACCUCCAUUUGCGUGUUUAAUCACCAUCUCAAGCUAAUGUAACCAAGCAGACUUCUUGGCCUUCAUCCCUGCCUCCUCUAGUCUUCUCAUCUCUCUCUCUCUCUCUCUCUUUUUGAGACAGAAUUUGGCUCUGUUGCCCAGGCUGGAGUGCAGUGGCACCAUCUUGGCUCACUGCAACCUCUGCCUCCUGGGCUCAAGCCAUCCUCCCAACUCAGCCUCCUGAGUAGCUGGGUCUUCCCAUCUCUUUAAAAAACAAUUCAAUUGUUCAGAACAAAACCCUGGAGUCAUAUUUAAUUCCUCCCUUCCUCUUGCACUUCUAAACCAAUCAUUCAUCUCUACUUUGAAAAUGUUUCUUUAUUCAUCCAGUGCACCAAGCCACCAUCACCUCGAGGCAGGAAUAUUCAACGGCCUCAUAAGUGGUCUCCCUAUUUGUGUUAUAUUCAAUGCAUGUCUUUUCUUACUCAAAAUCCUAUAAAGGCUUCUCUUCACCAUCCACGACUGUUUCCUGCCUUCCUCACUAUGAUCCCAUCACUGACCCCUCAAGACUAUGUUCCAGCCUACUUUCUGCUCCUUGACCAACACCCUUACUCUGAUUCCCACUUUUGUGACUUCACAUGAGUCCCCUGUCUGCCUGGACACUCUGCCCCCAACCUUGAAGUGCUCACCCUUCCCUGUCACUCAGUUGAAAGUCAAAUUCCAUUUCCUCAUGAGGGCUUCCCUGAAUACCCACUUUUAAUUAACUCUCUGCCUCCUCCCAUCACUUCUGUUUUACCCCCUCUUUUAGUUCCUUCCUAUCUUAGUUUCAUAAGAGCCAGGGCCGUUUCCGACUUCUUUCCCCGUCAAGCCUCCUUAGAUAGGACAGGUCCUCUGCCUCACCGACUUUAAUCAGUAUUUGCUAAGUAAACAGAGCACAGGAGGAUCCUGUUGUCAUCAAAGAGCAGCUCUGCCUCCAAUGGCGAAAGGAUUGUUGGAACCUCAUCCUUCCUUCAAGUUCUGGUUCAAAAAAUUCCAUGCUAUGCCUCACAUGGCCUUGCCCAGGUGCCUGUUUGAUUUGCCUGGGUUGUCUGUUCUUUCUUCCCCACUGUCCUCAUUUGCCAUGUGGCUCGGUGGUGGCUGGAGACCUCCAUGCUGGCCCCUGGGAGCAGCUGCUAAGGCUCGGCGCCUCAGGACACCUUGGCACCUGUGGAUAUCGACCACCAGGCUUCUCUUCUGUUCAUGUCUCUGCAAGAAUGAGAACCUGCCCCCAUACCAUUUGUGCUGUGUAGGCCUCAGGAGGCAUGGACUCACGCAUCCAGCUUCCUGCAAGCCCUCUGGUACAUCGCAGUGUUCACCCCCAGCUUUCUAUUACAGCCACCACCCAGGGACUCUGGUGCAGGCUCCUUAGAGAGAGGCCAGGAAACUGCCGAGGUGAUAAGUGACAGCAGGUCUCAGGGGAAGAGAGGACUUCUCUCCUUAGUAAAGAACCUGUCGAGGUCGGAAAGACACUCCAGGCUCAAAGCCAAAUUUGAAAGUUAGGCUGACAGCCCAACUAGGGCAGAUUGGAGGAGCCAGGUGGAGAGAGGAUGUGGGGGAGUCAGGAAAGAGGUGGAAGGAGAAGCCUGGAAGAGUGGCUCCGCUCCUGGAGUAUGGCCAGCGGCACUUCGUCAGGACCUCGACCUUCACCCACUAGUGGGAGGGUGUUCCUCGCAUGACUUGUAGGAUCACCUGGGAAACACACAAAUGGAAGAAUUUAAAAAUAUCUGCUAGGACACCCCGUGUCCCCCACAACUCAUCACAGAGCAAACCCAUCACAGAGCAAACUCCUUGGCUACUUCUUGUCUUGGGCCGUCUUUUCAUCUGGCCUGUUUGCCUGACUGGACUUUGGGGUCUUUGUUCCCAGCAUCAAAAUUUCCUACCAGCGACUUUCCAUCACAGCUCCCUUCCAGUCUUCUGGAAAUUGUCAGAUGUGCCUGGAUUUGCAGGGCCUGCACAAGAUAUGCUGUCGAUCUGGGAUUUUUGGGGAUUUUUGCAGUUCACACUCCAAUGUGCAACAGCAACCAAACGGAGAUGGAGGACGUGAACAUGAACUACUGGAGAUGCUGAUGAAACGUGUGUAAGGACCGCAAUGGUAUCUGUGUCCUGCUCGUGAAAUUGACCAGAUACAGCGGCUUCCUUUUGCUUCCGAAGGCCCGGAUUGACCUGACAAUUGAUAUGCUUUGCUCUAUACUCCAACUCCCAUUGACCAUGGGGUGAAAGCACCCUUUCUCGGUCAGCCUCACUGCUUCCCCGCAGAUGGAGGGAUUUUCUGCAGGAGCAUGGGCCCUGGGCCUUCCUUUCCCACUGUCUCUUGAAAGCCUCCUCCAGAUGUGCUGCCUGGCUCAGCUCUUUGGGUGACUUUUGUUCUGUCUCAUGUGACCCAUCAAGAUUCACACAGGGCUGUGUCCCGGGCAGGGCUGGAGUCGACAUUCAGGGAGGAGAUCACUGUUCUGGAACAGAGCAGUGAUUGGUUUAAUUGAAAUCUGAUAGAUCAUCAUGUAAAAAGCUGGCAUGUAAGCAUGCUCCCGGAGCCUGCAGGGCCCUGCGCGGCCUCUUGCCUGGCCAUCACGUAGAGGCGGUCCUCUUGCAUGGUUGGGGGCCUCACCUGCACCACGGGCCCCCAAGCCAAACAGUGAGAUUGUACGGAGACCAUCCUGGUCAGGUCUUGCAGUUUGCACCAGGUAGCCCCAGGCUAUCCUGCCGUGCAAGAGCUGCCUUCUCAGCACAGUGGAGUUCUACGGCUGCCUCGGCUGCAGAGGUCAGCUCUGGAGCCUUGCUGAGCACCUCCAUGGAUGCAUUUUGCAAAGGGCCGAGUAAGAGGCAUUAACGUGGCCUGUGCUUAGUUCCUGACAGCAAGCGGGAUUAAACCCGGAUUAAAGGAUCAGCCCUAAACCAAAGCAGACCAGUAAUAGGUCUCAUGAUAAAAGCAGCCAAAUAAUAAUAGUAAAAAUCUAUUCUUGGACUU

Taxonomic tree

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Publications