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Homo sapiens (human) cancer susceptibility 17 (CASC17) URS000075E2D4_9606

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CASC17: CASC17 is a non-protein coding gene located on chromosome 17q24.3 and has been observed to influence nasal shape [PMC7346930]. It is part of the CASC family of long non-coding RNAs (lncRNAs), which includes CASC15, CASC17, CASC18, and CASC20 [PMC6128939]. SNPs in CASC17 have been found to be protective in certain conditions [PMC8616752]. The CASC17 locus, near KCNJ2/SOX9, has also been implicated in lung function and prostate cancer [PMC6081985]. In addition to its role in nasal shape, other genes such as SOX9, DCHS2, PAX1, RUNX2, GL13 have also been found to influence nose shape [PMC6198798]. The annotation of well-studied lncRNAs in dogs includes HOTAIR, MALAT1 (NEAT2), NEAT1 (NEAT1_1), PCA3 (PRUNE2), as well as the canine orthologous relationships of the CASC family of lncRNAs and INHBA-AS1 [PMC7646326] [PMC6128939]. The annotation of these lncRNAs provides insights into their potential functions and evolutionary conservation. Overall, these findings highlight the importance of non-coding genes like CASC17 in various biological processes and their potential role in disease susceptibility.

Genome locations

Gene Ontology annotations

Sequence

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GGGCAAUUCACCUUUUCUUUAAAUACUCAUGUCACAUUUGUGCUGUUGCCAAUGCUUCUCAGACCCUCCAGAUGAGGACAUUUCCCUGAGGAGGUGGCUAUGAUGGUAGAACUUACAAGACUUCAGUGGACAUAAGGAGACGGGGUCAAGGUGGCAGGCAAGAUGGUCAAAUAGAAGUAGCUUCAGUCUGCAGCUCCCAGUGAGAUCAACACAGAAGGAAACAAUGCCAAGAAUACGUUAAUCUAAACCCAUGAUGUUUCUACAUCUCAAAGAACAGAGAGAAAAGGAAACUGGAGAGAGGCCAGAAGUGACCAACUCUAUUCCCUCAUUUCUGUGUUAUACUCCCUUUGUCUAAUCUUCCCUACCCUACCAGGUGGUUUAAGAAUUUUAUCCUUUCUCCAGACUAGAAGAGGAAGUGGGGGCCGGAAUUAGGUGUAUACAAAUUGUUGGAAAGCCUUUGUGUGGAUUUGGAGGGCUGAAGUAGAGUAUCAUUUUUACAAAGCAGCCCAAGCCUCUAAUCUGAGCAGGAAGAUUCACACUCAUUCUCUGGCAUGAGUCCUAUCAGGAGGAUCAAUGAAGCCAAGGCUGUAGAAAUAAAUAAUUAAUCUCUCCACCCAAGGAGGCUAGUAAACAAUAUUCAAUACGUGAAUACUGAGUUCUGCCAAGAGGAAGAAGCAUAUAAACCAGGCAACUGCUGAACGCAUUGCCAAAAAGGGAGACUUACGCAUCAUUCACUAAAGCUUUCCAAAAACUAAAUCAGAUCCAAGAACAGAUAAACUCCUGCAGAAUGACAAUGGUGGAGAAAUUGACCUCCCAGCAUUGCAGACUUACAUCAGUUGUUCUGAUGUUCUUAGUUAUAUCAGAUUCCUUCCAGAAUCUUCUAAAUAUAUCAGACGGUCAGACACAACCCCAGGCCCUAAUAAAAAACCCUGAUGCUGGCCUACAGAUGUGCAAUUUAAUAAACUUUCUCCAUGAUUCUGGUACACAUCCAACAUAGAAGAACCACUUAGUACUUCUCUCUGGCUCAUAUUUCUUCCACUAUUUACUAAAUGUCGACCUUAGGCUAAUUUCUUAAAUCCGUGUCCAAGGGUUUCUUUAAAUGGAGAUAAUAUUACCUUAUCGUCAAUCUAUUGUAAGAAUUAGAUAAAAGGGUGCAUGCGAAGGACCAAGCAGUGUAGAUGUCACACUGUAAGUGCUUAAUACGUGUCUCAGCUUAUUAUUCUGCAAGAGAAGUUAACUACCUAAUAAAUUGUGUAGAUAUCAAGUGCCCCUCAUGGCACUUUAAUCAAAGAAAUCUGUUGUUAAUUCCUAUUGUAAACCUCAGUUGCUACAUCAGCCAGCUCUUCAAAGGGAUAAAUAUGACAUUAUUAUUUUCUAAAUGACUUUUAUUUUCUAAAUGCUCUUAGAGUGUUUGAUCCCCCGGAAGCUAUCAUCAUUAAUGAUUUCUCGAGUAUACUGAGAGUAAUGUUUAGGUGUAAAGGAAGUGAAAAGUAAACAUGAAUGCUUCUUUGCUCUUCAAAGAUGAAGGUUCUGAGAUCAAAGAGCCUGAGUGAUGUGACCACAUCCCUAAAGAUGGUGCCAAAUGCCGCCCUACUGAUAAGGCUGCUGUGGGGACCGUGCACCUGUGUUCUUCUCUUAAUACUUACUCUGGGUCUCUGUUGACAAGGAACAUUUUGAAGUUUCUAAGAAUUAUUUAAUAACCCUAAUAAUCAUUGUUUCUUUAGUGACUCAAGUCUACACCUGUAAUGCUCAGGUUUUUCUUUCUUUUUUCAAUCGGGGAACGUAUUUUUUUUUUCUUGUAGUCUCUUAAAUAACAGAUUAUAUAAUAAAAAAGAGAAACUUUCUCAAGAAGGAAGCUAUCUGCACUGCUCUGCUGAACUCUAAGCCACCUCUGCUACUAAAACAGAUAGUAGCCCCUGUUGGGGUCUCUGGAGCAGGGAAAUCCAAGCUGUCAUGGAGCAUGUAUUCAGUAACCAAAGAGGAUUCUACAAGUUUUGUUUUUCUGGCUAGGUGACUUCAGCCCAUCAAAGACAAAGAUGAAAUAAAAUAAUCUGAAUGAUCAAAAAAAAAAAAAAAA

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Publications