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Homo sapiens (human) long intergenic non-protein coding RNA 1405 (LINC01405) URS000075E0AF_9606

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LINC01405: LINC01405 is a long non-coding RNA (lncRNA) that has been studied in various contexts. In a study on cardiac muscle contraction, LINC01405 was found to be associated with this process, along with other lncRNAs such as C10orf71−AS1, LINC00844, MIR133A1HG, PCAT7, and PRKCQ−AS1 [PMC9119753]. In another study on tongue squamous cell carcinoma (TSCC), LINC01405 was found to be consistently downregulated in TSCC and associated with poor clinical outcomes [PMC7456846]. Additionally, LINC01405 was identified as a prognostic biomarker for TSCC [PMC7456846]. In the context of MELAS (mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes), LINC01405 was found to be significantly downregulated in muscle biopsies of MELAS patients compared to controls [PMC5282567]. Furthermore, LINC01405 has been identified as one of the top downregulated differentially expressed genes in various conditions such as muscle-related disease and rotator cuff tears [PMC9470226] [PMC8957827]. Overall, these studies highlight the potential role of LINC01405 in cardiac muscle contraction, tongue squamous cell carcinoma prognosis, MELAS pathogenesis, and other muscle-related conditions.

Genome locations

Gene Ontology annotations

Sequence

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CCAUGUGAAGAAGGUGCUUGUUUCCCCUUUGCCUUCCGCCAUGAGUGUAAGUUUCCUGAGGUCUCCCAGUCAUACUGCUGGUUAAGCCUGCAGAACGGUGUACUUGUUUGAAAUGUAUCUGGCCCAAUCGCUGAGCGUCCGCGCUGCAUUUCUCCAAACUGCCCAGCAGGGGGCGGUGCUACCUCGGCUCCGCGCAGCCACGGCUUCCCGCUGGCGAACCAAGGGCGCGGAAUCUGGAGAGGGCGAGGAACAUCUUUCCUCCCACCUGUCCCCCGCCAAGCCUGCCAGACCCGUCUCAUCCGUGCUGCUGCUUCUGAAAAUCAGAAGAGUGAGGAUGAAAUAAAGUCUUCAUAAAGGAAAAAAAAAAAAAAAAA

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Publications