v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) HLA complex group 11 (HCG11) URS000075DE27_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

HCG11: HCG11 is a long non-coding RNA (lncRNA) that has been implicated in various cancers, including glioma [PMC6797506], pancreatic carcinoma [PMC8266358], breast cancer [PMC9876628], vascular endothelial damage [PMC9106501], osteosarcoma (OS) [PMC8457558], non-small cell lung cancer (NSCLC) [PMC8188752], hepatocellular carcinoma (HCC) [PMC8457558], gastric cancer (GC) [PMC8457558], and colorectal cancer (CRC) [PMC9981294]. It has been shown to play a role in inhibiting cell proliferation and tumor growth in breast cancer and OS cells in vitro [PMC9876628][ PMC8457558][ PMC7784567]. HCG11 has also been identified as a potential biomarker for OS and NSCLC [PMC8457558][ PMC8188752]. In some cancers such as HCC and GC, HCG11 has been validated to be an oncogene [PMC8457558]. It has been found to interact with various molecules such as miRNAs and proteins [PMC6961147][ PMC7255475][ PMC7541137][ PMC9876628]. Furthermore, HCG11 has been shown to regulate the expression of genes such as BRMS1 through miR-942-5p [PMC8131154]. In CRC cells specifically, it was found that HCG11 silence could promote apoptosis while inhibiting cell proliferation, migration, and invasion [PMC9981294]. Overall, HCG11 appears to have diverse roles in different cancers and could serve as a potential diagnostic and prognostic marker as well as a therapeutic target in cancer treatment.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
CACUGCAAGAGUUCCGGUCUGGCAGAGAGCGCGGAGAGACGCAGAGCGCGGGCCGCUCCUCCAGGGCGCUCCAGGCCCUCCGGCCCCGGGUCGGCGGGUGAGCUAGGGGGCGCCCCGGGACAGGCCGCGCCCUCUGCCCUGCAGAUACCGGAGGCCUCUGCUGUGGCUGCCCACUGGCUGGGCCCAGGCCUUGAAGCGGUGGCGAACGUCUCUUCCCUACCCUACCUCGGUGACUGAUGGCGGCGGCGGCCUCUCCCAGUCCGGACCCUGCCGGCCGUCGGGUCUCCCGGCCCAAGCCUGCCGGGCCUGGACGAAACCCCCGCCGAGCAGCCUGGACGCAGCGCCUUUGGGUGGCGGCGGGAGUAGCGUGCCGGGAAGCAUGGCGGCCGCUCGAACGCCGCGCGGCGGAGGGCGUUAGGGCAUGGAGGGCCCGGGAAGGCGGCCUAGGGACGCAGGCAGGCUCGGCCGCCUCUUCAGGCCACGGAGCCGCCAGAUCUGGGUCCCGGGUGACCACUCUGUCGCCAUUGGGCGAGACCUACCUAGUCCUAACGACAACGGACAAAGGCCUUAACGGGCCUGGGAGGUGAGCGAAGUCCCGAACGACGACGGGUGGAACGGUUAGCGGCGAUCGGGCGGUUGGUCUCCGUACUACCAGACCUUGCUGUCGGAAGAGACAAAUGGUAGAAUGACAGGCCACGUUUGGCCCGUUGGAAAUGCCCUCCAUCCUCUGGGAAGAUUCACAGGCCGUUUACGGAAGGCCUGUGUAUAUAAUAUGAAAAAGCUGCUCUCAACUCCACCCCAACCUUUUAAUAGAAAACAUUUGUCACAUCUAGCCCUUCUAGAUGGAAAGAGGUUGCCGACGUAUGAUAGAGUUAGAAAGUCACACAUCUUGUAAAUUCUCAUUUGUUUAAAAGAAAUCAUAGAAAAUACAUGUCUUCCGGAGUUGACUUUUGGAAACUGAGUUGUUAGACGGCCUCUAGAAGCGAUACGUUCACGUUUGUUCAGUGGGUUAGAUGACAUGGAGCUCGAAGACCUGAGAAGGAAAAAAAGAAGGUUCUAUGCUAGACUGGUCAUAUUUAGAAGACAUUUUCAUAUUCUAUCCAUUGUUUUGUGUGCAUUCGCUUCCUCACUACUAUGUAUGUAGUUGACAAUGCUAAGCUUUUUUGAAAUGUCUAUUCUUUUUAGAUAUUCUGAAGUGUCUGAUAUAUGUUAAAAUUAGAGGUAGUAAAACCACAUUUUGUAAAUAUCUUUUUGUUACAAUUCAUAGAAAUGUUGUUUUUUGGGGGGAAUGGCCAAAUCACCUGUUGAGUAAUACUCAUUGUGUUUGUGCAGUAGUUCAGGGGAGGAGAGAGGAGGGGGAGGUGCAGAGAGCUCUAUGCCAUCCUGCUUACAGCGAGGCAAGAUGAAUCACUAUGUCUGUGCAUUUUGUUUUAUCUAUGUAUAUAAUGUACAUAAAGGACAAACGAGUCCUAAUUUACAACAUCUAGUCUUUCUGGAUGUUAAAGAGGUUGCCAGUGUAUAACAAAACUAGAGUUAGUAAACUAAUAUAUUUUGUACAUUUUGUUUUACAAGUCCUAGGAAAGACUGUCUUCUGAAAAUUUGAGCAUUCUUGCCCACUGGGUUGAUGGAGAUGGGAAGGGUUCUAGGCCAGAAUGUUCACAUUUGGAAGACUCUUUCAAAUUAUAACUGUUGUUACAUGUUUGCAGUUUAUUCGAGACUGCUGUGUACAUACAUAGUGGACAAAUUAACUCCUUACUUGAAACAUUUAGACUAUCUAGAUGUUUAGAAGUGCCCGAUGUAUAUUAAAUGUAGAGGUAGUAAAAUACCAAUUUGUAAAUAUCUUUUUGCUAAAAUUCAUAGGAAAUACUUUUGGAAGUUGAAUUGUGAAGCCACCUUUGUGAGCAGUAUAUUACUGUCUAUACUUGCUCAAUGGUUUAGAGGAGGUGGGAGGGAAGAAAUUGCAAAAGAUAAUAUGCUAGUGUGUUCAUACUUGGACAUUUUCAGACACCAUUUUUCUGUAUGUUUUGUGCAUUUUGUUUUGCUCUGUAUAUAGUGUAUAUAAUGGACAAAUAGUCUUAAUUUUUUAACAUCUAGAGGUUGCCAGUGUAUGACAAAGUAGUAAAAUUAGCAUAUUUUGUAUGCUUUGUGUUGAAAUUCAUAGGAAAACUUGUCUUCUGUAAUUGACUUUUGCAUAGGAAUUUGUUCAGCCAUCUCUAAGCAUUACACAUGCGUGUACUUGUCCACUGAAUUGAAGGCAGAGAAGGAAGAGAAGAGGGAAUGAUUCAAGGCCAAAAUGGUCACAUUUAGAAGAUACCUUAGAUGAUAACCAUUGUUAUGUGUGUGCAGUUUUAUUUAACAGUGCCGUGUACAUGGUGGACAGGCUAUGAAAUAUCUAGUCUUUAGAUAUUUGGAAGUGCUUGAUGUAUUUUAAAGUAGUAGUAGUAGAAUAACACUUUUUGUAAAUAGCUUUUAAAAACUGAUGGGAAAUGCUGUUUGGAAGUGGAUUUGUUGAACCACCUGGGAGGUGGGAGGGAAAAAAUUGCAAAAGGUGUUUUGCCAUUGUUUAUUAGAAAAUUUCAGCUUAAUCCAUUGCCUAUAUGUUACAAGCAUUUCAUUUAACUUUGCUAUACUGUAUAUAUUGUGUAUAUACUGGACAAAUGAGUCCUGAUUUUAUAAUAUCUAGUCUGUAGCUAUUAAAGAGGUUGCCAGUGUAUGACAAAAGUAGUUAGUAAACUAACGCAUUUUGUACACUUUGUUAAAAUUCAUAGAGAGGCUGUCUUCUGAAAAGGACUUUUUGGAAGUGAAAUGAUAACAUCAGCUCGAAGUGACACAUGUGCUUAUAUCCACCAGGUUGGUGGUGGAGAGGAGUUGGAAGGAAUGAAGGGUUCUAGACCAGAAUGUUCCUAUUUAGAAGACACUUUCAGAUAUAACCAUUGUUACAUGUGUGUAGUUUAUUCAACAGUGCUAUGUAUAUAGUGGACACACUUAAGUCCUUAUUUGAAAUAUCUAGUCUUUCUAGAUGUUUAGAAGUGCACAAAGCAUGUUAAAAGUAGAGGUAGUAAGUAACACAUUUUGUAGUUAUUUUGAUAUGAAAUAUUGUCUUGGAAAUUGAUCAAUUCUCUGAGAAGUACACGUUAUGAUAUUUGUGCUGGUUCAGGGGGAAGAAGGAGCACAAAGUUCAAAGGGCUUUCUACCAGUGUCCAGUGUGUUUAUGAUGAGGCACAUUGACCAUUGUCCCUUAUGUCUGCAUUUUCGUUUACUGUGCUGUGUAUAUAAGCAGACAUAGGAGUCCUAAUUUAUAUCUAGUCGAUGUUAAAGAGGUUGCCAGUGUAUGGCAAAAGUAGAGUUAGUAAACUAAUACAUUGAGUACACUUUGUGUUAAAAUUCAUAAGGAACACUUCUUAAAAACAGAAGUAAAAUUGUUAAACGCCCCCCGCCCCCAAGCAUUACAGAUGGCUUAUAGCUGUCAACGGGGUUGGUAGAGGUCAGAAAGGGAAGUGUUCUAGGCCAGAAUGUUCCUAUUUAGAAGACACUCAAAUUAUAGUCUAUGUUAUGUAUAUAUGCCAUUUAUUCAAUACUACUGUGUAUAUAAUGGAAAACUUAAGUGCAGUUUGAAACAUCUAGUCUUUCUAGGUGUUUAAAAGUGCACAAUGGUCAGGUGCGGUGGCUCACUCCUGUAAUCCUGGCACUUUGGGAGGCUGAGGUGGGCAGAUCACGAAGUCAAGGGAUCGAGACUAUCUUGGCCAACAUGGUGAAACCCCAUCUCUACAAAAAAUACAAAAAUUAGCUGGUCGUGGUGGCACAUGCCUGUAGUCCCAGCUACUCGGGAGGCUGAGGCAGGAGAAUCGCUUGAGCCCGGGAGACAGAGGUUGCAGUAAGCCGAGACCACACCACUGCACUCCAGCAUGGCGACAGAGCAAGACUCCAUCUCAAAAAAAAAAAAAAAAAAAAAUUCCACAACAUAGGUUAAAAGUAGAGGGCUAAAGUAACACCCCUCUAAGCAUUUGUUUUCAGUACUUCCUAGGAGUGGUUGCAUUUGGGAAUGGAAUUGUUAAAACUUGAUGCUUAGGAGCGUAUGCUGACUAUUCACUGCGUGGUGGGGUGGGGAGGAGGAGGAGGUAUGCAGGGAGAAGGGUUCUGUGCCCCUGAGUUAGAUUAGUUCAGAUGGUCUAACCAUUGUUCUAUGUAUGCAUUUUAUUGUGUUAAUAUUGUGUAUUAAAGGAUAAACAAGUCUUAAUGCUCAAAGUAUGUUAAAAAUAGAUGUAGUGAAUCAGUCCCUUUGUGAAUGUCCUAUUGUUAGUUUUUAGGAAGGCCUGUCUUCUGGGAGUGACCUUUAUUAGUCCACUUCUUGGAGCUAGACGUCCUAUACUUAGUCACUGGGGAUGGUGAAAGAGGGAGAAGAGGAAGGGCGAAGGGAAGGGCUCUUUGCUAGUAUCUCCAUUUCUAGAAGAUGGUUUUAGAUGAUAACCACAGGUCUAUAUGAGCAUUUUUAGUAAAGUGCCUGUGUUUAUUGUGGACAGAGUUUAUUAUUUUGCAACAUCUAACCUUUAUGAAUAUCUGAGGUGACAAUGUGUGAUAAAAACUAGAGCUAGUGGGCCAGGCGCGGUGGCUCAUGCCUGUAAUCCCAACAUUUUGGGAGGCUGAGGCAGGCAGAUCACAAGGUCAAGAGAUCGAGACCAUCCUGGUCAACAUGGUGAAACCCCAUCUCUACUAAAAAUACAAAAAUUAGCUGGGCGUGGUGGCGCGUGCCUGUAGUCCCAGCUUCUCAGGAGGCUGAGGCAGGAGAAUCACUUGAACCUGGGAGGCGGAGGUUGCAGUGAGCCAAUAUUGCGCCACUGCACUCCAGCCUGGGCAACACAGCAAGACUCCAUCUCAAAAAAAAAAAAACUAGAGCUAGUGAAUUAGCCAAUUUGUAAAUACCUUUUUAUAAGUGAUAGAAAAGAUGCAUCUUGGACAUGGAAUUGUUAAACCGCCUCUGAGCAGUAUAUGUCAGGACUUGUUCAUUAGGUUGGCAGCAGAGGGGCAGAAGGAAGUAUACAGGGAGAGAUGUAUGCAGAUGUGUCCAUAUGUGUCCAUAUUUACAUUUUGAUGAUAGCCAUUGAUGUAUGCAUCUCUUUUGGCUGUACUAUAGGAAUACAUUAAGUAAUUCAAUGGAAAUAUACCUUGCUAAUAUUAUAAUGGUAUAGCUCUGUUAAUGAAUUCUCUUAGAAACAUUAUACUUAAUGUAUUCUGUUGCUGUAUGUUUCAUUUUAAUUGAGCAUUAAGGGAAUGCAGCAUUUAAAUCAGAACUCUGCCAAUGCUUUUAUCUAGAGGCGUGUUGUCAUUUUUGUCUUCUAUGAAAUUUUUGUCCCAAGAAAGGUAGGACUACAUUUUUUUUUAACAGAUUAAGUUGGUGUAGUGUAUUCUUGUUUAUCAAAAUACUAAUAAAGCUUUGGGAUUUUGAAUUGGUAAAUAUUCAUGAUGUGUCAAAAAUCAUGAUACAUACUGUACAAUCUCAGUCCCAUAAGAUGGGAUGUUGUGCCUACACACACACAGGACCUAGAAGAACAUGUCAAACUGUAAACUGCUUGUGAUUGUGAAUGACUUUGUUGUUUGCUUCUUGUGAUUUUCAGUUUCCUAUAAUGCACAUAUUAACAUAUUAACUUUUUAAAAUAAAGGUUAUUUUAAAAGCCUGUUUAAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications