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Homo sapiens (human) long intergenic non-protein coding RNA 2035 (LINC02035) URS000075DD27_9606

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LINC02035: LINC02035 is a long non-coding RNA (lncRNA) that is part of a 13-transcript gene expression signature for Kawasaki disease (KD) [PMC7011927]. This signature includes eight genes, including LINC02035, that show increased expression in KD compared to other conditions [PMC7011927]. Additionally, five other genes in the signature show decreased expression in KD [PMC7011927]. To further investigate the subcellular localization of LINC02035, as well as the transcription factor RUNX2 and another lncRNA called LOC100130207, immunocytochemistry and RNA in situ hybridization assays were performed using human primary chondrocytes isolated from knee cartilage of osteoarthritis (OA) patients [PMC9760429]. These assays aimed to determine the presence and localization of RUNX2 protein and both lncRNAs within the chondrocytes [PMC9760429]. In summary, LINC02035 is an lncRNA that is part of a gene expression signature for KD. It shows increased expression in KD compared to other conditions. Further research has been conducted to investigate its subcellular localization using human primary chondrocytes from OA patients [PMC7011927] [PMC9760429].

Genome locations

Gene Ontology annotations

Sequence

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CCUUUGGUUUGAUUGGAUUCAUCAUGAGGCAGCAUGGGUUUGCACUUGUAGAAAUCAAAACUGUUAGGUCAGGUAGUAAAGCCAAUCCUUGAACUUACAUCUUUAGUUAAGGCAUCAAAGAAUUGUAAGUUGCUUUGCAAUGAUGCCAUCUCCACAUGGUCAGAUUCUUCCAGUAAACUGUGCAGAUAUUUUACAGAAUAAGAGCUAAGUUUCAGCAUGUCAAGGAAUGAUCUGUACUCAAGUGUUAGUAAACAAGGGUUUUUUUGUUUGUUUGUUUGUUUUGAGACAGUCUCUGUCAUCCAGGCUGGAGUGCAGUGGCAUGAUCAUAGCUCACUGUAUCCUCAGACUACUGGGCUCAAGUGAUCUUCCUGCCUCAGCCUCCUGCGUAGCUAAGACUACAAGCGCAUGCCACCACCCCUGGCUAAUUUUUUAUUUUUUAUGGAGAAGGGGUCUCACUAUGUUCCCCCAAGCUGGUCUUGAACUCCUGGACUUAAGCAAUCCUCCCACCUCAGCUUCCCAAAGAGUUGGGAUUAAAGGCGUGAGCCCCCAUGUCCGGCCAACAAGACUUCCUCGUGACUAUAAUGUGAGCAUAAUAUUAAUAGCUCUGAGAGAGAGAAGUGAACCAGAAGACCAACCUCAGUGUCAGGAAGUCUGGGCGUCUGUCUUCUGCAUGGCUGAAGACAUGGGGCUUUGGGCAAGUCAUCUGUUCUCUUUGAACUUUGGCUUCCUCACUUCUGAAAUAGGAGGGUCAGAGAAGAUGUUUCUUUUUGCUGAAAAGUUUUACAGUUCUCUGAUCUAUACCCCUUGGUCACACACAACCAAAAAGUAGAAAACAUGAGUGCAAUACUUUUCCACCAGUACUCCCAGUUUAUACAUUAUCUUCUCAAACCAAUAAGGAACUUCUACAAGGCCCUGUUAGUGAUGUGUUACAGGUGCCAGCAUUAGGGAAACUUUCAGACUGUUAUAUCUAUUCGUUCCUUCAUCCAUGUAUACUAUUCAUUCUGUAUGCAGAGUAAUUUAUAUAUGUACAAUUACAUGGCAGUGAAAGAUAAUCAGAAAAAUGAAGUUUUUUUUUUUUUUUUGAGAUAGUUUUGAGACAGAGUCUUGCUCUGUUUCCCAGGCUGGAGUGCAGUGGUGUGAUCUUGGCUCACUGCAACCUCCGCCUCCCGGGUUCAAGGGAUUCUCGUGCCUCAUCCUCCCGAGUAGCUGGGACUACAGACAUGCGCCACCAUACCCAGCUAAUUUUUGUAUUUUUAGUAGAGAUGGGGUUUUGCCAUGUUGGCCAGGCCAUUCUCGAACUCCUGGCCUCAAGCGAUCCUCCUGCCGGCUUCCCAAAGUACCGGGAUUCCAGGCAUGAGCCACCAUGCCCAGUCAGAAGGUUUUUUUUUAAAAAACACACUCCUGAACUAACAAUUACAAAGAGCUAGUGACAAUUUCCCAAAUAAUUAUGCAUAACAGGAGCCCAUAUAUUGUUCUCAAAUCAUAAACCAUAACUGAUUUUGAGGAAAAGACAUUCUGUCCCACUGAUAUUCUUUUCAUGAGUAAGAUCUGGAUCUGUCUGGAGGCACAGAAUUAAUUUUUGCAUGAGGAAUCCCAACCCUACCAUCAUUCCAUGGCUGAGGAAUUGGUUAUUACUCCUAUGGGAAAUUGGGAAUGUUGUUGGUACCCCAGCCUUCUCUUAAGACAAAAUUUAACAAAUGCAUACAUGCUAAGAUGCUUAUACUCAUAAGGCUUUGUGGGUCUCCUUUCUAAGGGGAAUUUGAAUACUAACAAGAACAAAGGCUAAAUACCAAAAGGGGGCUUUCUAAUGGUAGAAUUUGGGAUAUCAGGUAGCCACAUAGAGCAGGGCUACUUUGGGGGCUGGAGACUGCAGAAACCCUUCAGUUUAUACGUGUGAGUAAACCUAAUCACACUUGAUGUAUUGCUAGUGAAGUCCCAGCCCCCUGAGCCUUUGCAGAAACCCAAAGAAUGCUAAAAAGGGCAGGUUUUAGUUCCUGCCAAUUAUUUCAUUUACUACAAAUGCCCCGAGUUCCGAAUUUACUUCCCUCCCCACCAGAAAUAUGUCAUUUUGGAGGCUUGUGAAAAUUAAGCAUUAAGAAAAUCCCGCCUCCAUCCUAAUACACUGCAUCCACAAGUCCCAAACAAAAUCACUUCCUUGGCCUACACACAUAACUACCUGUUUCUGUUUAGGUCUGUGACUCAGAAAGUGCCUGGAAGAAGUCAUGAGAGGGAGUCGAUCCCAUCUUACCUGCCAUAGGAAGAAUAGGGCCUGCUCAGUAGAGUUCAGUGUGUGUGUUGAAGGUGGUGGUUCUUAGUCCUUCCCUGAAUUCACUAAUUCGCAUUGCACUCACUCUUCCUGAUCAAUGAGUUAUUGCUGAGAAAUCAUUGUAGUAAGUAAUACAGGUAUCCCCAGUAAAGCCAUCCCUCUCCUCCAUACCUCCGCUGUCCCUUGGGUUUUGGCUCCAGGAUCCUUGCCCCAUGUCCCAAAGAAUCCCUACCUUGGGCCUCCCUCCUCCUCUUUUGUCAAUUGCACUUGACCUUUUCAGGAAAAAGAAAUCAAUUGAUACCUUAGUCCUAAUGUUUGACCCUUUUCUAUCUCAGAAUAGAGAAGUCCCUGUAUUUGUUCUUUUUUUACUCAAGUUUAAUAUAGACCACCUAGGCACAGAAGCUCCGUGCUAUAUUCUGUUGCCUGUAAUUGUCCUUCCAUCUAAUUGGGAAAAGGUUACUCUAUUGAACCAUCUGCUGAUUCCCUUACCUUUUCACUCUUUUGUCAGUAUUCCUUUACCAGUAAAUUCUUGGUUAUCUAGGUCCUGAAGUUUCAUUCAUGUUUUUUUUAAAAGCUUUAAUUUUUCUUAGGAAAACUGUUUCUCUCAUCUUAAAGCAGACUAUGAUCUUUUCUACUUUGUUAUACAAUCUGAACAUAAUGAACACUCUAAAGUCAGGCAUGGAUUUUAUCAUAAAAGCAGAUCGUAUUAAGAUUUUUUUAAAAAAGAACCAGGAUUGAGGAAUCUGUAGCUAAUAAUUUAAUAAUUCACCAGCAUGUUUUGGGCUCCCACUUCAUGCUGGCCACUGGGCUAGGCACUGAGGGUGCAGAAGCAAACAAAUCAGCCUCCUGGCCCUCAGAUUUGCAUUCCAGUGAGUCCAUUCAUAAAACCUAACUCAAAGCCAGCAACACCCCCAAAAGGGCUGUUGGAAGCUUUGUAGCUCAUCUGUACAGCUGUCUUGAUUCCUGUACGGGAUCUUACUUUCUUGGGAAAAUAUGUUCUAAAUCCUGUUUCCUUGGGCCAUUAAAAAUCCAUGCUGUCCCUAAUCAAUAUAUAGUUAUGUGUGACCUUCUUAGAAUUAAAAAAAUGCCGCUGGACAGCCUUUGAAGGGAAAGGCAGAGAAAUCUGUUUUGAUGGCUUGAAAAUAAGUGAAAAGGUUUUUAGGGAAAGCUAACAAGCUUUCAAAGAUUUCAGAUCUGCCAGCAUUCAUUCAUUAAGGCAUGGGAUUAGGCCAAAAGAGCCUCCUACCAAGGGAGAGACAGGAACCAUGUAAGGAGAUCUGUGAGACCGCAGUGGAAGAGUAUUGAAAUAGAAGCCAGACCUGUAGACGUAUUUGUUAAUAUGUGUGCCAAGCCAAAGUACAGGAGGAGGCUUGGAGGCAUGGAGUUGUGGUGGAAGCAGGUUCUGAAAAGCAGAACUCUGAAGCUGGCUCAUUCUCACGAAGUCAUCUGGCCCAGCCUCCCGCCUCCAAGCACAUCCUGCCUGCAGAGGGUCUGGCUAGCUGCCUUUUCAGCUCUCGAGGGAUAGAGAUUCUACAACCUCCCUCUGUCAUCAGUUCCAGAGCCACUCCCCUUUGCACUAGAAGUUCUUGCUUUCAAAGAAUGAGGGUGUGAGGGAGGGAGGGGUCAAGAAACAGAGUGACAGGGGAAACAGGCAGAACAAGUCAGGGCAAAGGACCCCAGCAUGAAGAGUUGUGGAGGUGGAGGUGGGGAAGCAGCCUCACAUCUCACACUUCCUUCCUUCUCUUAAAUGUGAGCAGCUGACUCCAAGCCUUGUGGAAACUCUAGAAGGUAGAACCAGCCAUCUGGGGAAGCUGGCCUUACAGAUGCCCCGUCUGGCAUAGUGGAGGUUCCUGUGCUCUGAGAACGCAGUGUGAAUCUAGACAUCCACUGCAGCCUGGGAAGAGCUGUGUUUUCUUCAAAAGUCUUUAACUUUCACAGUCACCCCUCUAAAGAAAUGUUCUCUGAUUGAAGGCAUGCUUCUAUUCCUACUUUAUUGUGUUUCAUGCAUUCUGCCAGAGUAAUUACUUUUCAUACCAAUUCUUGGAUGCAGAGAAAUCUCUGGUAGUCUAAGGGGAUUUCGAUCCAAGUAAAGCUACUAUCUCCUAUUCCAUCCAGACUUUUCCGUCUGCCUCCAUUCUCUCAGUCACAUACCUAGAAGCAAGCCAGAAAGCCUGUCCAACCAAAAUCACUCUCCAAAGCCCAAGCACUUUAUUGUUCUCCCUGUCUGUUAUCGAGCCAAGGUGUAUUUGGCCUCAUUUUAUGCCAUUAGUUGUCUGGCUUUCAUGGCUCUGCACCACAUUACAGUCAGAGCAGGAAGGCCAGCAGUGGAGAUAGAAUUAUGGCAGAAACCCAGAGUAGAGGCCUCUGCUGGUGAGGGAGCCUGCAGCACUCUCCACGCUGGUGGGUCCUAGCAUGCCCAACAGACCCCCAUCCCUUCCCAUCAGCCUUGGGCCUUGAGUCUCAUUCCAACUCAUCCCCUCCCCUUUCCCUUCUUUCCAGUCCCAGGUGACACUUGAUGCCUCUGACUCCUUUGAAGAGGGCAUCAAGAAGUGAAAGAACAAAGUCCUUUUCUGUUCGGGAUCUGGGCCCAUCCUGGGAGAGGUUUUUGGCAGAAAUGGCUGCAGUGGAACCCUCUGACUGCCAGGGUGAAAUAGUGCUCCAGCAGGCUGCGGUAGACUCACUGCCAGAGUGGGUCAGGACUGGCCCAGAGGACAGGGUCGUCUCUUGAGAGUCCUCCCAGCUCCAGGGCCUGAUUUUAAAGCAGUAACACGAGGAUAUAGGUUAUAUACAGGCUCCUGGAAGGCAGGUGCCGCAGCUCCUGUGACACCCCAUAUGCCUGAGCAAGCUUCUCCAGCACAAGAGAUGAUGCAAGUAUGAAUGGGUACGGGGGGAGCUUAAAACCUGCCAACACUGAGACUUGAUGCCAGGGGCCGUGCACCCGCUCUGCCACCUGCUAGGUCUGUGCAAUGGUCAGAGCAGAGGUGUGUGAUGAGUUCAGCUCCCAAGCACAUCCACACUUAGGAAGUGUUCUGUGUGUUUUUAAAUAAUCCUUACCAUGUAAAGAUUGUAUUACAUUUGUAUACAAAAUUUUUUUGCAUUUUACUUUUGUAAUAUUUGGGGUUUUAUAGAUUUUUAUUUUAUGGCCAAGUAUACUUUUGUAAGGAAAUGUUGAAGUCUUGAGUAUUUUUAUUCUUUUAAAAAACUAUAGUUAGUGUCAACUGUGAGCACUGAUAAAUAUUAUUCAUGUGUGGUUUUCCUUCUUUUUAAUCCAGACUUUUUAAGAAACUGUUUUGGCAUAGAGCUUUACUUAAAAUGCUGCUUCAUUUUACACAUUGUGAAUACUGAAGAUUCUAAAAAAUAAAGAUGCAUUUAAAAUCUCUGUGCUGUUCCAUUGUAGAAAUGGUAAUGUGCAUUGCUUUGCCAAAGUGGUAAUUAAAUGUUUAAUGGUUUAGAACUCCUAGUUCACAACAGGGCUUCUCGUCAUCACUUGCAGCGUGUGAGCUUCCAAAUAAGCCGCCAUUUCUUUGGAAAACGCACGCACUUAGGCAUGGCGAUCUCCUGUUCCGUUAGGAAAUACGGUUAUGUUGACAUUAUGGUUACUGUGCUUGUGGUUUUGCAAUAAACAUGUAUUGAAAGCA

Taxonomic tree

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