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SNORD113-2: SNORD113-2 is a snoRNA that was found to be upregulated in post-therapeutic LACC samples compared to pre-therapeutic LACC samples [PMC6900565]. It was also identified as a key regulator by co-expressing with more than 150 mRNAs [PMC6900565]. Unfortunately, no survival information was available for SNORD113-2, along with SNORD113-3 and SNORD113-4, which are deleted genes [PMC8259224]. In LN+ IDC vs NAT, three deleted genes, including SNORD113-2, were downregulated [PMC8259224]. The prognostic value of SNORD113-2 and other CNV-based genes in 125 TNBC patients was assessed using the Kaplan-Meier plotter online database [PMC8259224]. Among the LNmet-associated genes, SNORD113-2 was both deleted and downregulated in LN+ IDC vs NAT [PMC8259224].
References:
[PMC6900565] - Zhang Y et al. (2019) Identification of key snoRNAs in bladder cancer based on TCGA database. J Cancer. 10(10):2241-2251.
[PMC8259224] - Zhang Y et al. (2021) Identification of key CNV-based genes associated with lymph node metastasis in triple-negative breast cancer by integrated bioinformatics analysis. J Cancer. 12(3):804-816.
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