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Homo sapiens (human) long intergenic non-protein coding RNA 661 (LINC00661) URS000075DBB7_9606

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LINC00661: LINC00661 is a long intergenic non-protein coding RNA that has been found to be upregulated in tumor tissues compared to normal tissues in cholangiocarcinoma (CCA) patients [PMC8674813]. Along with CHRM3.AS2 and MIR205HG, LINC00661 has been identified as a potential predictor for CCA prognosis and a powerful indicator for CCA patients in clinical practice [PMC8674813]. These three DEARlncRNAs (CHRM3.AS2, MIR205HG, and LINC00661) may play a role in CCA progression [PMC8674813]. Dataset GSE107943 was used to validate the predictive power of CHRM3.AS2, MIR205HG, and LINC00661 [PMC8674813]. Further investigation is needed to confirm the exact roles of these lncRNAs in CCA through in vivo and in vitro experiments [PMC8674813]. The expressions of CHRM3.AS2, MIR205HG, and LINC00661 were significantly increased in tumor tissues of CCA patients, supporting their prognostic prediction value [PMC8674813]. A predictive model for overall survival (OS) based on CHRM3.AS2, MIR205HG, and LINC00661 was constructed [PMC8674813]. The expressions of these lncRNAs were examined using quantitative real-time PCR (qRT-PCR) on clinical samples [PMC8674813]. The constructed prognostic DEARlncRNA signature relied on the biological functions of these lncRNAs in CCA [PMC8674813]. Reference: [PMC8674813]

Genome locations

Gene Ontology annotations

Sequence

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AGUUGGGGCCUGGUCAACAGGGGUCCAGGAGCUGAGGCCUGGUUGGUGGGCCGUCUAGCAGUUGAGGCCUGGUCAUCUGGGCCCGGCAUUUGGGGCCUGAUCGGCGGGGAUCAGAGCAGUGAGGCCUAGUCAGUGAGGUGUGGAUGUGGGGGCCUGGAUGGACGUGGAGGAAGACGUGGCUACCCUACUUGCACAGGAGCAGGGGGCAUCAUUGCCCAGUGUGAGCAGUGAGACGUAGCUGCCACCCAUCAGUGCCCUGGAAGUGAAGAGAAGACAUCAGGAGAUGAGGGACACAGAAAAAUGGCUCCAGGUGCUUCUCGACUGCCAGCGACAUAGGAGCGGCAAGGAGAGCAAGUAAUGACGCCCUCCUCCCAGACUUGCCCCAAAGCCCCCCAGAGCUUGGUGGUGUCCCAGGACGGUCCUCCCAGGAAACAUUUUGAAUAAGUUGCUGAAGUGCCUGAUGGACGUGGCUCUCGUCACGAAAUGAGUUUGGAUCCGAGAAGCCCUCUUCUUCAUCGGAAAACAGUGCCUCAUCAAUGAAGUAAGCAGGCAGCUACGUUCUGGAUGGCUAGCAUGUACCGAAGGCACAAAACCUCCAGAGUUGGCAGAGUUAAGUCCUGGCGUGCCCGAGGCUAUCCAGGGGAACACGCGGGACAGACAGCACCCUCAGCCUGUCCCCAUGACCCUCUGCUCCAGUCUGAGGGGCAGGACACCAUGAGACCUCUCAGACACAGAGUCCACCCUCGACAUGACCCGGAUGAAAGGCAGGAGUGUGCUCGCUGAAGGGGACCCAUCUCUGCAAGCCCACAGCCCUACCUGCAGCAUCCACAGCCUCAGAGAGCAGCGGGGCCCCUUACCCCUGAACCCCCUCCAAGAGCAUCAGGACAACAAGCCUUGAGCUGUGGAGACAAGAGAAUCAGUAUCCCUGGCCCAGGGAGGAUUCCAGGAGAGGACACGGGCAGGAGCCCUGGCCCAGAGCCAGAACCAAGAGUCCAGCCAGCGAAACUGGAACUAGGGUCCCCGGCACCCAGGACUCUGCGAGCAUCCCCCAACAGCAAGCCCUUCUGCAAGGGAGACGGGUUGGCCCACCCCAGGCUGUCCAGCUCCAGCAGCCUUGCAGGCAGCCUCUCCAGAAAAAGAGCCUGGUCCUCCCCACCCUGCUCCCCACAGGCUGUCCCUGACCCUGAGGCCCAGAGGCACAAGAGGACUUCUGUAGAGCCCAGGGGAGCAGGCUGUUCUCUUGGGGCCCCAGCGGGCUCAAGGUGUGGCCAGGCUGUCCCCAACUCAGGAUAGAUCAUAGGCUGUCCUGCGUACCUCCUCUGGAACUCCCUGCCCAAGCUCUGCCAUGGACCUGGACGUCAGGGGCCUGUGGUUUAACUUUGAAUAGGGAUUCUGGACCUUACACGUGUGCCCUGGACAGCCCCAGAACCAUGGGGUGGGGACCGACCCAGCAAGCCCACCGGGGCCCUGAAACCCGGCCCUGCCGGACACUGUGAUAAUAACCAAGAGGCAAGUCCAGAGACAUCCACUUUGCCCAAUGGCACCUGCAUCCAACUUCUCAGCAGGCAGUGACUGGCAUGGUGUGGGGGCAGCCGGGGCAGCACCUGGCCAGCACCUGGCCAGCUGCCCUGUAGCCCCCGAUGGCUCCAGUGCCUCUGGACCUCAUUUUCUACUUUCUACGGGGAAACCUACUCCCUCAGAGGCCACCAGAGGGAAGAGUGAGCAAGGCGUUCCUGCAGUCCCGACCAGCCAGCGGCAUGUCCUGUGGCCUCUGACUCAACCUAUGAGACAGAGCUCUGAUCCCAGGGCACACUUCCCAGGACACGGGGCCCAGCCUCAACCAGAGCCCUGUGAAGGGAGGGGCACCAGGAUGACCACAUGGGGGACCAUGGCGCUGCACACCUGGGCACUGUACUUCUCAUUGGAGAAUCCAGGCAAGAUCUUGAAGCAGGUGCAUGAGGUCCUGAGCCUGUGCAGCAAACAGCACUCAUCUGGGGUUGGCACGAAGGGGUCUACAGAGCCACGGCCACCGCAGCCUCUUCCCGGCCCCAUCUGUGCAGUGCAAGUGAUCCACGCCUGCUCCUAAACCCAGCCCAGCAAGCAGCAGCAGCCCGGGCCCCCAAGCCCGCCAGGCCAAUGUGCUGCCCAGAGGCUUCGAGGCCCUGCCCGCUGUACCUCCCACCACCUGGAAGCUGCCUCCUGACGCCUUCCAGCCACUGCUGCAGCCGCAACAGGUGUCGCGGCCAGUGCAGGCUUUCCAGACGGUGGCAGCGCCCAGCAGCCGUUGCCUCAGCUCUUUGGUGGCAGCCAGGCCAACAAGGGCAGCAACGAUGACUAGGAUGAUGAGUGAGCAAACAGCUCCACACUGGUGGACAGGCUGGGUGCGCACCCGGUGGUCCUCAAAGGCUCGCUGGGCCUGUACCACCGUUAUAAAUUUGAGAUCAUGAGAUUAUACCGUUUGCCUUCUUGCUUUUUGAAGUACGAGUAUUUUUAUGCACACUUUGUAGACUUCAAAAUCCAUGAAGAGUCUCAAAGAAGCCGGAUGGAUGGAGCCUGCUGCGGAUGCCUUUUACUCUCGUAGAUCAGGGUGAUUUACAUUCCACCUGUAGUCUGCUUGCAAACACACAGAGCAGCCUUGCAGCUUUGUGCCUUUAGACUCUUGGUUUUGCAUUUCUCCCUGCUCCCUUCUUCCUUCCAGUAAGCUGCAACUUUUCUGAUUGAAAGGGUGCAAGGCUAACACACGGAAUGACUAACUCAGGAUCACAUACUGGCAGUGGGAGAGGCAGGAGGAGCAGCUGCCAUCAAUUGCCAGGGCCAAGUGGAUGAUAGGAUGGAUGCUGGUGCAUGCGGAGGAGGCAGACGCAACGCUCAUCUCUAAUAAUGAUGUCUGUUCCCUCAGAGGCGGCUAGAGCAUCACCUCUUCACGCAAGUGUCUUGAAACUCAGCUUGAAGAUUUCAGCAAAUGUGUCUUACAGAGAAGAGAAGAGGGAGUCAGCCCAUCGGGAUUAAAAAUAUAGAGGCAGUGACAACACACACUCGGCUUCAGUUCUUAGGAGAGUUUUGGUUUUGAUUUUUUUUUUUUUUUUGGAGAAGAUUUUUUUUUUAAUGGAUCUACACUGUUAACUGAGACUCUGUUGAGAUUCACUGGUUUACUUAAAAACUUCUCAGGGAUGUCUGUAAAUUUCAGUGUUAUAUGUCAUGAAAACUGGUGUGGGCAGAUCUGUUGGUUGAAAUAAUUUCUACUGUUUCAAAUACUGAAGGCAGGAAUAAUUGGUUUAUACUGUGUUUUAAAUAGAAGUAUUACUGGUAAGUCCCCCAGGACAUUAAACCUUAAAAAUCAGUAAAAAAAA

Taxonomic tree

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Publications