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Homo sapiens (human) family with sequence similarity 66 member E (FAM66E) URS000075DA44_9606

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FAM66E: FAM66E is a long non-coding RNA (lncRNA) that has been identified in various studies. In one study, it was found that FAM66E, along with other lncRNAs such as PVT1, XIST, FTX, AC078846.1, lnc00294, lnc02381, MALAT1, AC016831.5, and Lnc01184 showed upregulation after the addition of CaSO4/β-TCP ceramic polymer in co-cultured media [PMC9463206]. Another study identified FAM66E as one of the 24 lncRNAs expressed in their research [PMC8904995]. Furthermore, miR-21-5p was used to predict upstream lncRNAs and it was found that FAM66E was one of the eight intersecting lncRNAs [PMC9650007]. In a comparison between different cell lines and lung tissues, it was observed that the expression of FAM66E was lower in SPC-A1, A549, H1299 and Calu1 cells compared to BEAS-2B cells [PMC6166069]. Additionally, qRT-PCR analysis showed downregulation of FAM66E in lung adenocarcinoma (LAD) samples without lymphatic metastasis compared to LAD samples with lymphatic metastasis [PMC6166069]. Another study found that FAM66E could affect the expression of BCAR1 through a competitive combination with hsa-miR-92a-1-5p [PMC8158160]. Finally, a study on genetic losses observed a loss at 8p23.1 (FAM66E) among other loci [PMC4884971]. Overall these studies highlight the presence and potential role of FAM66E as an important lncRNA in various biological processes.

Genome locations

Gene Ontology annotations

Sequence

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GCAUGCGCGGUCUGCCUCCCGCGGCGGGCCGGGUCUCCAGGGAGGACCUGAGUUUUCUUCACCCAUUGUCAGGGAGGCGCCAUCGCCCUGGCUUUGGGGCUGGGGCCUCCGGGGAGGUUCCGGUAGGGGCGUUGGAGAGGCCGCUCUUUUUGCAAGGCCCGAGACGGCGGGCCCUGCGCAGGCCGCCCUAUUCCGCGCCCUCAGGGCGUCAGUAUCAGCCUGAGGCUGGAUACCCCCGCUGGGCCCGGAUGCCCCCGCUGGGCCCGGAGCAUCCUCCGGCGCUGCCCUCCCAGAGCCCCGCAGAGGCUGAGGUGGCGCGGGGGCGGCCCCGGCUCCGCGAGAAGCGGCGGCAGCGAGGGCUGGAGGACCCGGGCUGCGGGGCUCCGGGGCGUCUGGCCUGGGCGGGACUGAGCCCAUCCAGGGACUGGGACUCUGGGAUUCUGGUGUAGGUGGAUCCGGGGCAGGCUCAGGACCAAGUCCCUCUCCUUCCACCAAGGAGCGCCCAGAGGCCGGCGGGAGCUCCAGGUUCACCUCCUCCUCCUCCAGGAAAUCCCACUUCCAGCUAGAUGUCUGCAUGAACUACUGAAAGCUGCUGAGUGUCUUGCAGCAGCUUGACUACCACACAAAUGAAUCCACUCAAAUGUUGGCAAGUGGAGCAGAGUCCCAGGACAGGUACAGAAACACCCCCAGUUCAAGGAUCUUCACACCUGGAUUUAGGCCUACUCCUGCAACUACCCCAGAACCUGGAAUUUAUAUGUUCAACAUGGAGCCAUCCCAGCCAUGACAACAGAGAAUGUACCACUCUCACGGGGUAAUAUCGAGUUCCAGAAGGCAAGGAUUAACAUUCAGAAAAAUAGGAAAAACAACCUGCAGAGUUACUAUGAAUUAUUAUAUUGUGGCUACUUACACCAAGAUGAAGAUAAUUUAUUAGUUCAGGAAGAACCUGCAUUCUGAAGGCAAAUGGAAGUUCCAGCUACAGAUGGGCAGACACAUGCCCCCUCAAUUCCUGAUGGACCUCCUUGUGCCUCAUGGACCUAAGGGGCCUCCCUCAAUGUUUCAAGAUGCCACCAAGGCAGGGAUCAGCUAGUGCAUUCCUGAGAACAUCCAGGAUGAAUUGAGGCUCUGGAAAAAUGCAAGAGUUUCCACAUAAUCCCAAAAAACCCUACAGGUGAACUGGAUGCCACAGAAAGAGGAGUGGUCUUUGUCACAACAAAAUCAACAAAAUUAUUUCGAAGUCAAUUAGGAAACUCAGAAAUCACUCUUGCUGCCAUUAAGAGGAAGAACAGCAGCCUGUGAAUGGCAUCCCUGGCCUUCCCGAGACUCCACAGAUAUUUCUAUGUGGCUUCAGACACCAGAAAUCUCUGUGAUUUUCAGAAAGGCAGGGACAGCUCAUGCCAGCCCAUCCCUCUGCAGAAUGUGUCCCAGCAGAUCAGU

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Publications