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Homo sapiens (human) long intergenic non-protein coding RNA 844 (LINC00844) URS000075D3C8_9606

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LINC00844: To investigate the biological role of LINC00844 in hepatocellular carcinoma (HCC), LINC00844 expression was induced in HCC cells, specifically HepG2 and HCCLM9 cells [PMC6993750]. In a study aiming to construct a prognostic ferroptosis-related lncRNA signature (FRLS), 15 ferroptosis-related lncRNAs were identified, including SNAI3-AS1, GDNF-AS1, WDFY3-AS2, CPB2-AS1, WAC-AS1, SLC25A21-AS1, ARHGEF26-AS1, LINC00641, LINC00844, MIR155HG, MIR22HG, PVT1, SNHG18, PAXIP1-AS2, and SBF2-AS1 [PMC8170051]. Additionally, LINC00844 has been found to act as a competing endogenous RNA (ceRNA) for miR-785-5p and regulate the expression of pregnane X receptor (PXR) and drug-metabolizing enzyme and transporter (DMET) in HepaRG cells and primary human hepatocytes (PHHs) [PMC7692647].

Genome locations

Gene Ontology annotations

Sequence

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GUGAGCCAUGCCAAUGUGGUUUGGCUGGACUGUGAGUGCUUGAUGCAGUCUGAUAGGAGGAUGGGGGUGGCGCAGAGAACAUUGAAAUCAGAAAGGAUUCUGCUCUGUAGAGACAAAGGAAACACAGAGACAUAGACAUGGAUCUGGGAAAUACACCUUUUGCUACUCGUUCAGUUUUAGCAAGGAGGUUUCUUGCAUGGCUAAGCAAAACUUAAACUUCCUCUGAGAAUUACAGGAAUUACAGGACCUGACAAAGCUAUGAAGAUUAAAACCUAUAGGAAGAAAAUCUGAACCAGAAACAGUAUGGCAGAAUUGGGAUCUGACUCACAGAGGGAAGAACUUAUAAUUCUUCACAGGUCACAUAGAAGCAUGAGAAUUUGGGUUCAAGCAAGUAAAUUCUAAAUCAGAAUCCAUACAUAAAGUGUUUGCAAUGUCCAGUUAUAUCUCCAUGAUAUUUUCUUUGUGGAAGUUGAUUGUUCUUCCUUACAAUAAAUUGCUUGAAUUGUCUGUCUAUUCAUUUAGCUAUUUCUUUUCUUGUCUUUGCGAUAUUUUUUUUUGUAAGUAAAAAAUUUUCAGACUAAAUAACAGGGUGUAAUUUUUUGCUUUGUUUCUCCUAAGUUUUGUCUUGUUUAUGACAUUAAUAAUUUUCUAAAAUCUCU

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Publications