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Homo sapiens (human) CPB2 antisense RNA 1 (CPB2-AS1) URS000075D09D_9606

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CPB2-AS1: CPB2-AS1 is an antisense long noncoding RNA (lncRNA) that overlaps with the CPB2 gene [PMC6260132]. It has been identified as a potential target gene of miR139-5p and a candidate lncRNA that can competitively bind with miR139-5p [PMC7576003]. CPB2-AS1 has been found to be differentially expressed in various tissues and cell types [PMC8938286] [PMC6260132]. It is also an eQTL for CPB2-AS1 in multiple tissues, including cerebellum, basal ganglia, pituitary, and thyroid [PMC6260132]. However, the functional effect of CPB2-AS1 on the CPB2 transcript level is unknown [PMC6260132]. In addition to its association with TAFI and TAFI-AP levels, CPB2-AS1 has been implicated in various biological processes and diseases such as glioma [PMC8170051] [PMC7441444] [PMC9053788]. It is one of the lncRNAs used to construct prognostic models for glioblastoma patients and has been identified as an independent prognostic factor for IDH wild-type glioblastoma with MGMT promoter unmethylated status [PMC7441444]. The expression levels of CPB2-AS1 have shown an overall downward trend in glioma tissues compared to non-tumor brain tissues [PMC8170051]. Overall, CPB2-AS1 is a lncRNA that plays a role in various biological processes and diseases but its functional significance requires further investigation.

Genome locations

Gene Ontology annotations

Sequence

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AUGCGAGCGGUAAGAGUGCGGCGGGACUUGGAAAUCGAAUCUGUGCUCUGUGAGAGAUCCUAGGAAAGGAAACUGGGAGCCCGGGAGAACUAAAAUUCCCAAUUAAAAGUGAAUUUAAAUCUGAGCUGUUCUUAGACCCAGAAUUUCUUGCCUGAAGGAGGAAUCAGGUCCCCACAAGGAAAGACCCUGCAACUGUAUAAAAAAAGAAUCUAAAAAGAUCAUGACUCCUUCAGUCCUUUCCCAAAGAGACCUAUGGAAAUUUCCUCAGGAGCACCCACAACAGAAUAGACAUUAAACAGCUGCAUAAACAAAUGACUCAGCCAGUUGAUGUCAGUCAGCCUGUGUCAACAGCCACCCCAAUGCUGGCACAAAAGGCACUAGAACAGAAUAGCCUGAUGGCAGAGAUGAAGUGUGCAUGGCUCCAGCAGCACGGACUCCUCUCAUUAAGGCUGAUCUAGCUACUGUUGCUGCCCCAUGUCUAACUUGCCAGCAACGGAGACCAAAGUUGAGCCCCGGAAUCAGCACCAUUCCUCAUAGAGACCAGCUAGUCACUGGGUGGAAGAGGGACCAAGCAAAACCCCAGAAGAGUUGAUCUCAAAGCUUAUUUUAUGAAGAAAAUUGACCUGAGUGACACAAAGGGUUGGACUGUAGUAGAUGUCACGUUUUGCUGCCUAGAUCUCCAUCCAGGGAUGAACUCUUAUUUCCUCAGCUUCUUUGUCUCCUCAGCUUCUGGGAGGGUUGGCAGCUGAUAUUCUCACCUGAGUCCCUUUCUAGGACUUGCCCUUGCCUGAAGAGAGCUGUGCUGCCCAACAUGAUGCCUCCUCCAAGGUACAAUCCACACCCAGUGACUAAUAAACAGGGGUUACAAAGGCAUGCCUGCUUGCCCCAGUUUGGGACAACUUUACCAGGCCAACCCAGCCUCAAGGCUCUCCACAGGAACAGGUGAGGCCAUAGUUGUGAUUACAUCACAGGUCAGUUUCUCCUCUGCCCAAGCCUUCUUCCUUCAUUCCUCCACAGAUGCUGAUCCUGAGAUUCCUUUCCAGUAAACUUCCUCCAUGCAAUCUUCAUCUCAGGAGUCUGUUUCCUGGGGAAACUAACCUGCAACUGAUACAAAUGCCUAUUCUGUGAGAUAAAACACUAAAAGUACAAUGCGAGUGGUAUAAAUAUUCUGCUACAGGAAUACAAAGUCAGGUAUCAUUUUUGACUUAGGUAGUCAGAGAAUGGAGAUAUUCUGAGUUGGACUUCUGAGAUACUAGGAUUCAAUAGGUGAAGGGAAGAUGAGAUGGUAUAAGACUAACAUAGGCAGAAUUUUGCUAAACGAAUUGGAGAUGAAACAUCAUAAGUGCAGGUGCACAAGUAGAAAAGUAAAAUCAGAGCUCAAGGAAGGAGAAGUGAUCCAGCUGGGCAGAAAUAUGGGGCCUAUAUAGAGAUAUACCAGGAAAUAAAGCCAGGACGAAUGGCAGGGUAGGACCUGAUUGUUAAGGGUCUUAAAUGCUGGGGUCAAGAUUGUGGCCCUUACUUAAAAGUUGGUUGGGCAUGAUUUUGGGAGUUGUAGCAAAAGAUGUGGCAAACUCAAAGCUUCCUUUUCAUGUAAAGUAUAGAGAAGUGGAGGUUCAUAUCAUUAAAUCACUGUAAUUUCAGUGUGAACUUCUAACAAUUUGAGCUAACCAUGAGAUAGGACACCUUAUCAAGCAAUGAGCUCUUCAUUAUCUAAAGAGAUGCUGAAUUUCAAGUCCAUGUAGAGGAAGUCUUGUGUUGACUAGAGCAUAAUAUGUCUGGGGGGACUUUUCUUCUUUUUUACUGAUAUUUAGUAACUUGGAUAUUGUGCUAAGUGCUUUACAGGUAUUCUUAUUUAAUCCUCACAAGGCAGUAUGGUAGAUAAUCUAUUAUAUUGAAAAUAAUGGGCCAGGCACAGUGGCUCACGCCUGUAAUCCCAGCACUUUGGGAGGCUGAGGUGGGUGGAUCACCUGAGGUCAGGAGUUCAAGACCAGCCUGACCAACAUGGUGAAACCCUGUCUUUACUAAAAAUACAAAAAUAAGCGUGGCAUAGUAGCUCACACCUGUAGUCCCAGCUACUCAGAAGGCUGAAGCACGAGAAUCACUUGAACCCACGAGGUGGAGGUUACAGUGAGCCAAAAUCACACCACUGGACUCCAGCCUGGGUAAGAGAGCAUGACUAGGUCUCAAAAGAAAGAAAGAAAAUAAUGAACAAAAAAUGUUGAGUGGGCAGUAUUAAAUUAAAAAAAAACCUAAUGUAUUAAAGAAGGAGAAAAGUAUAAAAAUUAGUCAACAAGCAGAGAAAGAAAGAAAAUAUAAAGGUAAAAAUGUAUGUUAUCCAAAUGAGACCUCUUAAGAAGAAAAAAUAAAGGAAAUUCAAAAAAUAAGUUAGGAAAUAGUGAGUAAAAUUAUGAAGUUAAAAAUUCACCAAAAAUUUAUUGAUAUGUCCAAGUUCAGCUUGUAGUGAACAGACUCUUCUUAUGCAGAAUUUGAGCAAAGUGCUAACACAACAGAGUUAGGUAAUGGGAUGAGGGUCAGUCAGAUCACUCUAUUUUUGGAAACUGGUUUCAUGACUGCUUCCCCUUACUUAGUCAUAAACAGGCUAUAUAAAAAGCUGUCAGAGUGGAAAGAGGGAGAGGAUUUGUGAAUUUUUUUUUUUAGCAUGUUUUUAUGGUUCUGUAAGUCACCACCCUCCCAAAGGGAUGAAGUUUCGGGGUGCACUCCCCUUACCUCAGCCUAGUAGGGGGACUUCCAGGAGAUAAUGAGAGAGUUGGAUGUUUCCUCAAAUUUACAGACACAAAGACUGGUGCCUGGCUUCUCCUGAUAAAGCUAAACCUGCAUGUGGCUGGUCUCUAGUUGGCUAGAUAGUAGUAGUUAAAAUGAAAAGAAACACUUAAUGUUAGAUGCCAUCCAAUAGGGCCACCUAAAGGGAUGGAAGGUUCUCAACAACAAGAGCCCAGAGGUAGAAGCAAGACUCUUAGCGGGGAAGGAUGGAGUCGCAAGUGAAAACCUAGACAAAGAAGCAUCUGUCCUGGUCCAGAGGCUUCCCCAAUAAAGAUGUCUCACACAACUCUAAGAAGUUAGAACUCGAGAAAAAGACUAACAAGAAAAAGAGUAAGGUGUGUUUGUGGAAGAGGUGAGGCAGUUGUUUUCCUAUAAAUAAUGUUAAAUUAAACUAAAUUUGGUCUGAGGAUGCCUCGUAACUUGAGUCGCUACAUAACAAACUGCAACCUAACUUAGGAGUAUUUUUUUUUUGUACUAACGAGGUGAGUCUCAGCCAAUCACAGCAGCCAAGCUACAGCCAAUCCCAUGUGGCCAACUGAUCAGCCUAUGCCCAGUAAGACAACUGCUCACCUGUAACUACUCAAGCUGCUUCUGGACCUCAUUUCCAUUUGCUGUUUAUAAGUGCUGCCUGCCCACUUUGCUGAGCAGAACUCUCUGAACUUCUUUCGUUUUUGAGGGUUACUUGAUUAGAAAAUUGUUCUUUGUUCAAUUAAAUUUUGCUAAAUAU

Taxonomic tree

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Publications