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Homo sapiens (human) long intergenic non-protein coding RNA 1492 (LINC01492) URS000075CF6A_9606

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LINC01492: LINC01492 is a long intergenic non-protein coding RNA (lncRNA) that has been identified as a risk gene for left ventricular dysfunction (LVD) and is associated with small vessel disease (SVD) [PMC7642687]. It has been found to be upregulated in preeclampsia (PE), a pregnancy complication characterized by high blood pressure and organ damage [PMC6413561]. LINC01492, along with hsa_circ_0088196 and LIF, has been shown to promote the development of PE by suppressing miR-100-5p [PMC6413561]. The expression of LINC01492 is negatively correlated with miR-100-5p in PE [PMC6413561]. In addition, LINC01492 is positively correlated with LIF in PE [PMC6413561]. The upregulation of LIF, LINC01492, and hsa_circ_0088196 in PE inhibits miR-100-5p, which may contribute to the pathogenesis of the disease [PMC6413561]. These findings suggest that LINC01492 and hsa_circ_0088196 may serve as potential biomarkers for early detection of PE [PMC8572049]. Further investigation is needed to understand the etiology and pathogenesis of PE [PMC8572049]. References: [PMC7642687] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642687/ [PMC6413561] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413561/ [PMC8572049] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572049/ [PMCID8806450] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMCID8806450/

Genome locations

Gene Ontology annotations

Sequence

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AUAGAGCUAUGUUACAUUGAAUGGCAAAAGUGACUUUGUAGAGGUGUCGUUUAUCCGGAUGCUGCAUGAUUAAGACCACCAUACUCUUAUCAAGCAUACAGGUGUUAAUGUCUAUUUUAAAGAGGAGAGAACUCAAGAAGUUCUGUAGAAACUGCUUUCUUCAUCAUAUCUCAAAGGAUUUGCUGAGGAUUUCAGAGGUGCCACGAGUUGAGAGAAGACUUCGGACAUUUCACUUAAUGCUGAAAAUUCACUCUACUGCCACUACUCAGGACUUCUGAUGGGCAUGAAAAUCCAAGCCUGCUUUAUGAUAUUAACCUCUGAAUUUCAUAAACCGCUUAAAACUUUAGAAUGUCCAGAAAACACUGGUAGAAUACGGACACAUGAGACAAGGCCAGAAAGGAAGUCAAUAAAAUGUGAUUACUAAGCAAAUUACCACCAGAGAAGCAGAAGGAAAUCCCUCUUCAAUAUUUUGAGAGACAGUAAAGAACAUUCCCUGGAGUUAGGACAAAUGAAGAGCAAGAAGUUUCAUCUUGCUCUGUCAUCCAGGCUGGAGUGCAGGGGCACCAUCUCGGCUCACUGAAACCUCCACUUCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCUGAGUAACUGGGGUUACAGAGUGAAUAGACAACCUACAGAAUGGGAGAAAAUACUUGCAAGCUAUGUAUCCAACAAAGGACUAAUAUCGAGAAUUUACAAGGAACUCAAACAAAACUCAACAAGAGUAAAACAACCCCAAUAAAAAGGAAAGUGAACACAUUUGGAAAUAUUGGCUCAGCAUUGCAGCUAUACCCUUUAGACAGGAAACACACUUUCCAGUUCUCCUUGACAGAGAGGCUGAAGCUGCUUAUGUGUCUGGAAUUGGUGGGUUCUUGGUCUCACUGACUUCAAGAAUGAAGCCACGGACCCUCGCGUGAAGCAAUACAGGCAUUCAUGUCUGGACAAAAGGAAUAAGUGGACUACAUGCAGAGGCAGAGUGAGGCUGGAAAAUACAUCCUGCCAUGGGUAUACAACCCAAGCUAUCUAUGUAGAUUUUUUUUGUUUUUUUGAGACGGAGUCUCGCUCUGUUGCCAGGCUGGAGUGCAGUGGCGGGGUCUCGGCUCACUGCAACCUCCACCUCCUGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCAAGUAGCUGGGAUUACAGGCAUGUGCCACCAUGCCUGGCUAAUUUUUGUAUUUUCAGUAGAGAGGGGGUUUCACCAUGGUAGCCAGGCUGGUCUUGCACUCCUGACCUCGUGAUCCACCCGCCUCGGCCUCCCAAAGUGCUGGGAUUGCAGGCAUGAGCCACCACACCUGGCCUAUGUAGAUUUUUUUGUUGCCUUUUGAUUUUUUUUUUUUUUGCUUAUUCUGAUUCUAAUUGUACAAAUCAAUAAUAAAAAUGUUAAAAACAGACUUAAAAUAUUCAUGACUAUGCAAAUGAUUCAAAUAUAGUUAUUUAAAGUUUCUUUCUUUUUUAAAUUGGGACAUGGUCUUGCUCUUCAACCCAAGGCUGGGUGGCAUAGGUGAAAGAGCAAGACCAAGGCAUGACCAAGGCUCACUGCAGCCUUGACCUCCUGAUCUCGUUAUCCUCCCACUUCAGCCUCCCAAGUAGCUGGGUAUAGGCAUGCACCACAGUCCCCAGCUAAUAUUUUAAUUUUUUGUGUGUGGAGACAUGGUCUUGCCCUGUUGCCCAGGCUGGUCUUGAAUUCCUGAGUUCAAGUGAUCCUUGCUUCUCAGGCUCCCUAAGUGCUAAGAUUACGGGUGUGGGUCCCCAGCCAAAACAAUCUUCCUAGGGAAGCCCUCACAUUUUCAAGGGUUUUACCUUUAGUACCUCCAUAAAUUCGUAUCAAGCAACAAAAUGUACUGUCAAGGAACAAAAAAUAUAAAGGGACCUUAAAUGCAUAUUUCUAAGACCAAGAAGUCAGUCUGAAAUGGCUACAUACUAUAUAAUCCUAUAUGACUCCUAUAUGAAAGAUAUGACAUUCUGGAAAAGGCAGAACAAUAGAGUAAAAAGAUCAAUGGUUGCUUGGGUUUGGUAUGCAUGUGUGUUAGAGGGCAGGGUGGCUGGUGAGAGGAAUACAUAGGUGAAGCACAAGUGAUUUUUAUGGCACUGCAACUGUUCUGCAUGAUACCAUAAUAAUAAUAAAUGACAUUUUUCAUUUGUCAAAACACAUAGAAUGUACAAGAGAAAGAGUAGAACUUAAUGUAAAUUAUGAACUGUAGUUACUAUUGAUAUGUAAAUAUUGGUGUUCUAAUUGUAUCAAAUGCACCACACCAGUGAAAGACAUUAGUAAUAGGAGAAAUGUGUACGAGUUUGGGAGGUUAUAUGGCAAUUUCUGUACUAUCUGCUCUUGUUUUUAUUGUAAUUUUAAAAUUGUGCUAAAAUAAAGUUUAUUAGUUUAAUUUUCAAGAGAUUAAGAAUGUAUGUUUAAAUGUAAUAAUAUAUAUGCAGAGCUUUAUGUCUAUCCAUAUACUUCAAGCCAAAUCUACUUUUGGUGAGUUCGUCUGUUUAUAAAACACACAGAAAUAGGAAGAAAAAUAAUUGACAAAUAUUUACUAUGAAAUAACUUUAUAAGCAGUAAAUUGAAAGCACAUACAUAUAUUUUAAAAAGGCAUUUAUAUACUUAAGCAAAUUAUUUUCCAAAUAUAGAAUAUUAGCCAGCCAACAAAUAAUGUUUAAGAAAGUUUGUAAUUUUCUGAGACAAUACGGAUGAUAAAAUAUUAAGUAAAGAACAACUUUGUUGUAAUGUGAUAUAUAACAUGACAUAAAUAAAAAGAAAAAAUCUAGAUUAAUGUGUAGUCAAUAAGAAUUGCCAUGAAACAUUGUCAAACUGAUAUUUGAAAUUUAUUGUUUUAAAGCCCCUUAUAACUAAUAUUCUGUUUUUCCAUAUAAUCCUAUUAAUGUAUAAAUAAAAUCUUCUAUUUACCAAUUGGAUAUUAAAUCAAAAUAAUGUAAAUUAACAUCUACAAAUCAUAACUUUUCUUAAUGUUUAUUCUUUGAGAAUACAUAGUAGUUGCACAUAUUUAAGGCAUACAUGUGAUAUUUUGAUAUGUGUGUAUCACGUGUAAUGAUCAAAUCAGAGUAAUUGGGAUAUCCAUCACCUGAAACAUUUAUCAUAGCUUUAAAGGGCCAAAGCCAGGAUUUAACUCUCUUAGAUUCCAAAGUCCACGUUCUUAGAAAUAUUAAUUAAAAUAAUGACAAUGUUUGCCUCUGGGUUAUGCUAUUAUGAGAAAUUUAAUAUUUUUAAAGCAGAAAUUGAAAUUUUUGUAAUAGGAAGAUAUUUAAUAAAUAUGGAAAUGUAUAACUGAUUUUUUCUCCUAUGUCAUUAUUGUUGAAAGAAAAUCUUCAUAUCUUACGUAAAUAUAUUCUAGAUCAUCUGACAGAUUUUAUAAUUUCUCAUUAUAAAUUAAGAUUUUUUUUUAUUAUCUUCGGUGGUGAAAAAUACGCUCGCCAAACUGACAGGAAAAUGUAAUGUAAUGCUAAUUGCUUAAUUGAUUAUUACUAGGAGUCCACAAUUUUCAGUGCUUUUCUUUCUAUUUCUGUGUAUUUUAUAAAGAGACAAAUUCACCAAAAAUCAGUUUGGCUUGAAGUAUAUGGACACACAUAAAGCUCUGCACAUGUAUUAUUACAUUUAAACAUACAUUCUUAAUCUGUUGGAAAUUAAACUAAUAAACUUUAUUUGAGCACAAUUUUAAAUA

Taxonomic tree

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