v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) HLA complex group 18 (HCG18) URS000075CE1F_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

HCG18: HCG18 is a long non-coding RNA (lncRNA) that has been studied in various contexts. It has been found that reducing HIF-1α leads to a significant decrease in HCG18 expression in certain cells, suggesting a relationship between HCG18 and the stability of UBE2O mRNA [PMC8715259]. HCG18 has been shown to compete with PGK1 for miR-365a-3p, resulting in increased expression of PGK1 and aerobic glycolysis [PMC8903679]. Interestingly, HCG18 expression does not differ among different subtypes of breast cancer [PMC8715259]. In gastric cancer tissues, the expression of HCG18 is negatively correlated with miR-152-3p but positively correlated with DNAJB12 [PMC7413704]. In ovarian cancer cells, the suppressive effect of HCG18 knockdown on proliferation and migration is reversed by TRAF4 and TRAF5 overexpression [PMC8725507]. Additionally, HCG18 has been identified as a potential regulator in the pathogenesis of myasthenia gravis (MG) [PMC8600732]. The role of HCG18 in head and neck squamous cell carcinoma (HNSCC) remains poorly investigated [PMC9161984]. In hepatocellular carcinoma (HCC), promoting differentiation of macrophages to the M2 type may be a potential approach for intervention by considering the relationship between HCG18 and VEGFA expression as well as macrophage infiltration [PMC8435853]. Furthermore, it has been shown that elevated levels of HCG18 are found in patients with intervertebral disc degeneration or herniated disc [PMC5643303], and cholangiocarcinoma cells can transmit HCG18 to surrounding cancer cells through exosomes [PMC10104778]. Overall, these findings highlight the diverse roles and potential implications of HCG18 in various diseases and biological processes.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
CGGGGCGGCAAAACGUCCGCCCGGGCCCGAGGCGGGCGGAGGCAGCUGUGGUUACGUGCGGGGGGCCGGUGACGCAGUCGCGGGGCGCUGGGACGCGGCUUGCGGAGCCGGCCGGCGAGCGCAGGCCCCAGGCUCGGGCGCGGCGGCGGGACAGCACCUACCUUCCCGGCUUCGGGUCCGGGAGUGCGGGGCGCGGAGCCGCCGGAGCGCUGCCUCCCUCCUUCCUCCUCCCCUCGCCCCCGCCCCGCGGCGCGACACACAAUACUCGCCGGAAGCGGAAGCCGCGCCGAGGCUCGUGUCAGUGGAAGCUGGGGUGUCGGCGGGCGGCCGCGGCCGGGUCUAGCGGUGCCUGCGGAAGAAGGAGGAGGAGGGCUGGCGAUGAGAAGCAGCAGGGGGAAUCAAGGGCAAGAAGGGACCCAGAGGGGCAGGUGGCUGAGAUGCUGGCGUCCAGGUGACCCGAGGAAUCCUCUGGAGAUACAGGCCCGCGCAUGCGCGUGCUCGAGCGCUGAAGCCCAUUGCCCGCAGGGCGCUGGACUGGCGCCCCGGCCGGCGAGGCUGUCUAGUCCAGGCUCCAGGCCCCGGCUCUGGCCAGGCGCCGCCGCCUCCCGGUGCAGCUGAAAGUCGACGAAGAGGGCGGGGCGGGGGCGGCUUGUGGACUUCCACACUUUUCCUCUCUUCGGGCCAGUCUGGGGAGAGGGUGGCUAGCUGUGGCGGCGGCCAAUUACGUGGCGGACCUGCGGGGCUAAGCUGGCACGUCACUUCCGACUAGUGGAGUUUUUAGCCUUUUAACAUUCAAGGAUUAGGUAAAAGUCUUGCAGUGAAAAACCCGAGGACCCUUACCGCAAGUGUCUUUUGCUCCCAGCUACUGAUACUGGAUUCCACUCGUGAUUCUCCCUUUCUUAGCGCAUUCAUGAUAUAGACAUCAGUCUCUGAGCUGGAGGAGGACAAAGGCAGCGGUCCUGUGAAUUCUAUGCUCUAGCUUGGGUUAAGGGAUUUGGAAUUGCACUUGUUUCAGAGAGCUCCCUCUUUGCCCACUAGCAGGGCAUUAGCUGGUGCUGAAGACAGUGGCUGCUUGGCGAGCCUGGAUCUCCAAGUGACCCCCUCAGCAACUCCUGAUGAACAGGACUGAAGCCAAUAUUAAAGCAAGUCAACCAAAGGUUCUCUGGUGUAGACAAGACAGCAAAAGGACAGACUACCUUGUGGAACCUAGCAUUGUUCUCCUUCUGCAGCACUAAGUAACAUUUGUUCUCCGUUAAGAUCUUUGCAAACCACACACAAGAAUUGCUGGUCAUCCUGCCAAUAGAUGCUGCUCACAGAACCAAAUUUCCUGUGCUGAAUUGUCACUCAUGGGCUUGAGAGUAGGAGACUGGAGACCAAGGUGGCUAGAAUCCAGUUGGGCCUGAUGUCUCCCUGUUGAAAGGGCUCCUUGUGGAAUGAAUAGCACAUGGCUCCUGUGGUGGAUCUGAUAGUGGCAUAGCACCAAGUGAUGCAGGCCUGCCAGGGGCCACAGACACAGAAGAUGCUCCCGGGGUCCCCCAUGUACUCCAGACACACUGCAGGCCACCUCUCCCAGCAGGUUGCCAGUCAUGGGCCCCAUCAUCAUGACUUCUGUCCAAGGUACUGUGUGCAGAAAUGUGAUUGAGAUUCAAGUCAGGGCCUCUCUGCCCUUUUCCCUCCAGAAACAAAACCAAGAUAAUUUAUCCUGAACACGGUGAAAAAAGGAAGGGAGGGAGGAGAAAAAGUCCGGGUCUCACCUGGGAUUCUCUGUCUCCUGCAACAUGAAGGAUUUAGCCUGGGAGGAGGUGGUGAGAACUCUGGGAGAGAAAAAAGAAGGAAAGAAUAGUUUUACCCAUGCUGAAGUUAAUUUAAACCUUCACCUAGAGAAGCAAAAAAAAAAAACCCACACUUUCCCAUUUUGUGCCUCCCUUCCUAGAGUUUUAGCCAAAGGUUUAGCUAAGUAAUUGGUUUUACCAGCGCACUCACUCCUCCUAUCCCAAGUCUGUUUGACUCCCUCCCCAUCAUCCUCCUCACCUCUUUUCAGGCAGGGUGGGGAUAGCAGCAGGAGGAGAUUUUGGGAGCCUGGCAACUCCUGCAAGGACCGCAGGACAGCCCCUCUGUGGGGAUGCGUGGUGCCCCAUCUGCCGCCCUUCUGAAGAAUGCACUGCCUUCACUUUUUACUGUGUUAGAGUCCAUCCAGACUGUUCUAUCCAAAAAAGUUUCUUUUUCCCCCACAGGCAAUCAGGAAAUGAUUCCUUUCCCGACUGCUUCUGUCUAGUGCCUGGGAAUCUUGAGUCAAUCCCUCAGUAAGUCAGUGACUAGGGAAAUCCCUCUCUGAGCCUCCCAGUUCAUGUUGCUUAGGGAACCUGAUAUUUUCGUGAAACCUGCCUACACAUGGGCAGCCCAACAGCAGAACAAAUGGUGGUGACCAAAGUGAACAAAGAAGUAUAGUUGUGCCAGCUUCGUAGUUGCCCAUGUGGACAAGUCAGCAGGAUCAGGACACGAGGAAGAGUAAAUGUGAGACAGUCAAUGUGACUUCUGCGAUAAACAGAUUUUUAAACCCCGAAAUUUUGCAAAAUUUUGGUGAAACCUGAACUUUCUUCGUUGCAUAUACUGGCACUAUCUGUACCAUCAUACAACUGUCUCACAUUAAAGCUAUUUUUCUUGGGCACUGAUGAGUAAGGUUGGUAUAAGUUCCUCAGAUCAACAAAAACCCAUUUUCCUGUAAGUCUUACAUUUAGUAUUUAAGGAACUAAAACUUAAAUACAUUUUGUGAAAUGGUUGACACUUCACUGAUAAUGAUUUAUUGCUUGGAUUAAUAAAUUUUCCAAAAGUUGUCUUAUGUAGAAUAUGGUUUGCAACCAGCAGAACCAUUAAUCUAUACUGCAAUGAUAUGCACUAUGUAUAAUUGUUUAAAAGCCUCUACUUAAUGAUGUAAAAUGCUCUAUUUAAUUACACAUUUGGGUAAACUGUAUACUAACAUCUGAUGGCAUUUUUCCACUGUUUGUUGCUUUUUUCAAAUACUUUAUUGUACAAAGCUGUUCUUAAUAUUUUUCAAGUUUUUUUCUUUGAAUUUUGCUAAUGUUUUCCUUGAAUUAUGAGCACUGACAGAAUGUGCUUAGCACUUUUGGCUAUUCACACAGCUUUUGAGCAUGAUUUGCAUCCAAUAUUUACAUUGCUAGCAAUAAUAAGCCAUCUGUGAGUUUUGUCAAAAGUUAUUGGGGAUUUUUUAAAUUUUAGAAAUGCAAAUUAUUGUUUCUUUGAACUAACUCUUAUGCAGUUGCAAAGGCAUUUCCAGUUGUUAUAGUUUGUGUACAAUAUCAGGUGUUCCAGAUUAUGAUUCAUUAUUAAUAUCAUUGCUUCCUUGUUCCCUCUGAGGUCCAGAAGAUUCAUGUUUACAAUAUUUAGAAACAAUGUUAAAAAGGUAUCCAAAGUUUGUCACUUUAUUAUUAGUUUGUUCUUAAUAUUCUGUUUAAGUUUUUGAAUUCAUAGAUAUCAAAACGCUGCACAAUUAUGAUUUCCACAGGAAUAACAACACACUAACAAUAAGAACCAAAAACAGCAAAUAGGCUGCCUACAAGUUUUGACAAUAUUAGGAUAAUGAUAAUGACAGUUUUUCUAAAUCUCACAGUAAAGAAUGCAGCAACCCAGCAACACUGCUACCUGUGGCCUCAGGCUGCAGUGUCAGCUCUUCCCUGGGUCUCCAGCCUGCCAGUCUAACCUGAAAAUUAUGUACUUGCCAGCCCCCACAGUCACGUGAGUGAACUGGCCCAGGCUGGUCACCAGGGUCAGUUUCUCUGUGUGUCAUUAAUUCAUUCAGUCUUCAGCAGUCUCUUUGGAGCUGAGAUGUACCUACCAUCUGCCUUUUGGGUGCUUAGGGUGGAGAACCAGAAAAGUAUAACCUAGUGUGUAUCCUCAAAGAGCUAACAAUAUGGGGUGGUACCUAUAGGUCUGGAAACACUUUACUGACUCUGUGAGGCAUACCAGGAGACGUCAGAGAACAGUCCCUCCUCAAAUGCCAAAUGAGAUGCAGAAGAAAUAGUUUGCUCAAGUUCAUGGGCCAGAUAUCCCAGUGGUCAGGGAGUUUCAUGAAUGAGAUGGAACUUUGCAUGGAACCCGAGGGAUGUGUAUGAUUUGAGUAGAUGAAGAAAAUGAGACUUUCCAAGCAGCUAGAAGUUAGGGAGCAGCAAGAUGUGUGGUGGGAUUGAGCACAGUUGGUUCAGAGGAUAGACUGCAGUUUUAAUAAUUUGUAGUAAAUAUCUCCCAACUGUUUGGCACUAUUGGAGCAAGUUCUUGAAUGCCAAAUGAAGGCAUAAAUCAGUAAGAGGCAUAAUAAAAGGCUGAGCAGUGCUUGGCUUUUUACGAACUGAUCCUGAUAGGAGCAGCUGUUCAACAAAGUUGCCAGGUCACCGUUACAUAGUCCCUGCCUUCUAGGGGCUCACUGCCUACUGGGAGAGACAGUCUGAAAGUUGGUGGAGCAUGUAACUGUUGGAUGAGGAGUUUGAGCCUGUGGACUGUGGGACCCCCGAGGAGGGUGUGGCUACUCUAGGCAGAACAAUCCCACAGUUUAUUUAUAUUUAACCUUGAAAUUCAUUAGAGGAUUUUUCAGCAGAGGUUUGGUACUUGUUAAUGUUAAGGUUUGCAUUCUCUAGAACCUCAAGGAAAGCUGUACCGUGCAUAAUGUACCCUCUUAUGUUAAUGUUGUGUACUGUGAUCCUGUUUCAGGGACUUGCACUUAGGAAUCUGUUACAGUGAGCACAGAAGCAGACCUGUGGGCUCAUAGUCUUCACCCCCCACCCAUAUAUACAAGAUGAACAGAGUGGAGGUUAAACAACUUGACUAAACAACACAGUUCAUGGUAAAGCCCAAGACUGUACCUGCCCAUCCACUGCCUUUUCCAUGUAUCCUGGAACUGAGCAUAGACCUCUUCCCAGGCAGAGCUGACAGCAAGUAAAGGAGAUCAUAAUCAGGGGACCAAACAACUUUGUCUAAAGUGUGAAUGUCACCUAAGGAGAAGCUGUGAGAUCAGAAGGGUGGGGCAGAGGAGCAGACACCAUGAGGGAGAGUCCUUGGGGGUACAUCUGCCAGACUGACACUGUCUGGCCUGGGCAGUGGAGGGGCUAGCAGGAACCACAGGUACUGGUGGUGUGGCUACUACCGUUACAACUGCCUGUGCUUGGACAUGGACCCUCUGCAAUAUGCGGCAGUUUCAUUCAUUGCCCCCUACAUUCUACACCAAGUAGAAAUGGAAGGCAAUUGGAUACUUCACAGACAAGAUCUAAGUGGAGAAGGAAUGCGUCCUGUGGCUGCAGAGAUCCUUGGAGCUUGGAGGGGAGAGCUUGAGCCCCACUGAUGAUGACCUCCCACAGCUCGCCAACUCAGCCCUCCCUAAGUCCCCAUCGGGGGCCAAUUCUCACUCUGGGGUUGGGGGGACUCCACCAUAGCUCAUCCAUCAUAGGGAUGUUGGUAUCUACUGUGGGUUGGGUAGGGCCGAUGUGCUGAGGAUGGCUCCCCCACAAGCAAGAGAUGUGGAUUUGGGGAGCUUCCCAUCUUGUGUUGAAGGAACAUAACUCAGAAUAAUAAGAGCCAACUAUAACAAACCCACAGCCAACAUCAUACUGAAUGGGCAAAAGCUGCAGGCAUUCCCCUUGAAAAGUGGCACAGGAUAAGGAAGCCCUUUCUCACCACUCCUAUUCAAUAUAGUGUUGAAAGUCCUGAUCACAGCAGUCAGGCAACAGAAAUAAUAAAGGGCAUCCAAAUAGGAAGAGAGGAAGUCAAACUAUCCUUGUUUGCAGACAGUAUGAUUCUAUAUCUAGAAAACCCCAUAGCCUCAGCCCAAAAGGUCCUUCAUCUGAUAAUUUCAGCAAAGUUUCAGGAGACAAAAUCAGUGUACAAAAAUCACUAACAUUCCUAUACACAGUCGCCAAGCCAAGAGCCAAAUCAGGAGCACAAUCCCAUUCAUAAUUGCCACAAAAAAGAAUAAAAUACCCAGGAAUGCAGCUAACCAAGGAAGUAAAGGAUCUCUACAAUGAGAAUCACAAACGCUGCUCAAAGAAAUCAGAGAUGACACAAACAAAUGGAAAAACUUUCCAUGCUCAUGGCUAGGAAGAAUCAAUAUCAUUAAAGUGGCCAUACUACCCAAAGCAAUUUAUAGAUUCAAUGCUAUUCCUAUCAAACUAUCAAUUACAUUUUUCACAGAACUAGAAAAAACUUAAAAUUCAUAUGGAACCAAAAAGCCUGAGUAGUCAAGGCAAUCCUAAACAAAAAGAACAAAGGUGGAGGCAUCACAUUACCUAACUUCAAACUACAGGGCUACCAUGACCAAAACAGCAUGGUACUGGUACAAAAGCAGACACACAGACCAGUGGGACAGAAUAGAGAGCCCAAAAAUAAGGCCACAAACCUACAGCCAUCUGAUCUUCAACAAAGUUGACAAAAACAAGCAAUGGGGAAAGGUCUCCCUAUUCAAUAAAUGGUGCUGGGAUAACUGGCUGGCCAUAUGCAGAAGAUCGUAACUGGACCCCUUUUACUAUGUACAAAAAUUAAGAUGGUUUAAAGAGUUAAAACCCAAAAUUAUAAAAAUCCUGAAGAUAACUUAGGCAAUACCAUUCUGGACAUAGGAACUGGCAAAUAUUUCAUGAUGAAGACACCAAAAGCAAUUGUAACAAAAGCAAAAAUGGACAAAUUGGAUUUAAGAGCUUUUUCAUAGCAAAAUAAACAACAGGGCAGACAAUCUACCAAAUGACAGAAAAUUUUUGCAAACUAUGCAUCUGACAAGGGGCUAAUAUCUAGCAUCUAUAAGGAAUUUAAACACAGUUACAGG

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications