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Homo sapiens (human) colon adenocarcinoma hypermethylated (CAHM) URS000075CE0F_9606

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CAHM: CAHM is a long non-coding RNA (LncRNA) located on chromosome 6, hg19 chr6:163 834 097–163 834 982 [PMC10106610]. It has been identified as one of the top three genes significantly related to the prognosis of THCA (thyroid carcinoma) and is also significantly related to the targeted therapy of CAHM by anisomycin in THCA [PMC8056003]. In a regression model, CAHM was one of ten prognostic lncRNAs identified as having optimal ability [PMC9315452]. The level of methylated CAHM sequences in blood has shown potential for estimating the likelihood of a positive result being due to the presence of colorectal cancer (CRC) [PMC4164492]. The potential use of CAHM in cancer classification models, distinguishing between no CRC, early CRC, and late CRC, has been demonstrated [PMC4164492]. It is worth noting that CAHM was previously named LOC100526820 [PMC10106610]. Overall, these findings highlight the significance and potential applications of CAHM as a prognostic marker and therapeutic target in THCA and CRC.

Genome locations

Gene Ontology annotations

Sequence

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CGCCUGCGUGGGGCGGGGGCGGCAGCCGACUAGGGGCUGGGUCUGGCCGUUUAGGGCCGGGUCUUGGCCCGUCGCCCACGGUGCGGAGGGCUGGUGGGCUUUCCUUGGCCGUCGGGCCCGCCACGGCGCGGGUCUUGGCUGCGGGGCGGAGGUGGGGCGGGAGAGCCGAGGAUAAGAGUUUGAGGCUUUUCGAGGCGCGUGCCGCGGCGUCCGCCUCUGCGGGACUCUGCGCCGGGCGCCCUCGGCCGGCGCGCCCGGCUCCCGCUUUGUCGCCGAGGGAAGCACGCGCGACGCCCCUCCCGUCGCCGCCGUGGCUUCUUUCGGUGUUCGUGAUUUGCUGAGAGGCUGGAAAGCAGCACGGCGGAGAGGAGCCUUGCACUCGCCAGGCGGGAAGCCUGCGCGGACACGCGUGCGCACCCACGGGGCGGCGGGCGGGCGUGGGGGGUCCGGGCCACGCGGGCGACGCGCCUCUAGGGAAGCGAUCUUGUUGCACCUUCCCGUUAUUCUGAAAGCAAAUCGUAGCCAGACCCGAGCGCAGCGGCUUAGCAAAUAAUAAGGGGAGCGUCAGUCGUGCUCGAAAUGCUUCCUUCGCGAUGGCGUCAGUGUUCCGUGAGGGAAUGAAGCCGCAGUAGGAAAUAAAGAGGCUGUGCGCGUAGUCUGAAAAGCAGAAGUCAACAUUUUUACAGAUGAAGAAAGAAUACGGAGGCAAGAGGUCUUUCUCUGCAGUUUGGUGGAUUUCCAACAUUUAGACUUGUUUGGAAGAAUUUCCUCAGCUGCACCAAUGAAGUCCUUGAUCUAUAGAAGUCGGCAGUCCCUAAAUCUACGUCUGCAUUUUGUUGCAAAUCCUUUAUAACAUUCCAUUAAAAUAAUGCAGAGUUAUUUAAUAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications