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Homo sapiens (human) BAALC antisense RNA 2 (BAALC-AS2) URS000075CD5E_9606

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BAALC-AS2: BAALC-AS2 is an upregulated long non-coding RNA (lncRNA) [PMC4991477]. It is one of the two lncRNAs, along with PVT1, that showed upregulation [PMC4991477]. Among the lncRNAs with alterations in at least 10% of cases, BAALC-AS2 was one of the 10 lncRNAs that accounted for 40% of cases [PMC4991477]. Additionally, BAALC-AS2 was among the 15 lncRNAs that accounted for 30% of cases with alterations in at least 10% [PMC5647044]. BAALC-AS2 was significantly associated with overall survival in acute myeloid leukemia (AML) patients on univariate analysis [PMC9729799]. It was also found to be correlated with several mRNAs, including BAALC, HIF1A, TNFRSF14, IRF1, IL1R1, IL21R, RORA, and CA3 [PMC9845402]. Furthermore, BAALC and BAALC-AS2 were both upregulated after infection with La and L. mexicana [PMC9845402]. In primary human macrophages infected with La for 24 hours specifically, BAALC-AS2 showed upregulation along with GSN antisense RNA 1 (GSN-AS1), while BAIAP2 antisense RNA 1 (BAIAP2-AS1) and solute carrier family 22 member 18 antisense (SLC22A18AS) were downregulated [PMC9845402].

Genome locations

Gene Ontology annotations

Sequence

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ACCCACCGGUCUCCCGACCAGCGAGCAAGCUUUGGACAAGGCCAAAGAGCAUUGGGCUGCUGGAAGCUGGGGCAUCGGCGCAGCCUUCGGGGUGAACUUACGUGCUCGCUGACAAUGUCCUUAAAGUCCUGGCAUCCUCAGAGCAAGACAAAAAGAGUGGGGGCAAGCGAAGGUAACCCCCAGUGGGGCUCUGGAAGUAUGGAGGCCCCUCUCCUUUCCUCCUUCCUUCCACCUCUGGCCAGCGAGGCAGAACUCACAGGCAACACCUGGUUUCUGCACAGAUGCAGCUGCAUUUUGAACCUAGAGGAAAGCAUGGACAGCGACUGGGGGGCUUGGUGGGGGGUGUCGCUCCCUAGAAGGGCACCUUUUCUGAUAUAUGGGUCAGAUGGGCCUUGGUGCACACAGGCAGGCUUCCCAGGAUGGGGACAUUGACAAGGAGGCAACAGUCCUCUCUCCUCCACUCCAGUGACUAAUAAAAGCUAACAUUUAUGUAGCA

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Publications