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Homo sapiens (human) ERICH3 antisense RNA 1 (ERICH3-AS1) URS000075CAD2_9606

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ERICH3-AS1: ERICH3-AS1 is an RNA gene belonging to the non-coding RNA class, located in chr1: 74,577,430–74,626,098 (GRCh38/hg38) [PMC6993749]. In gastric cancer (GC), ERICH3-AS1 was found to be significantly up-regulated in cancer tissues compared to normal tissues [PMC6993749]. Higher expression of ERICH3-AS1 was associated with earlier recurrence and poorer prognosis in GC patients [PMC6993749]. ERICH3-AS1 expression level was an independent risk factor for disease-free survival (DFS) and overall survival (OS) in GC patients [PMC6993749]. ERICH3-AS1 expression was not related to age, tumor lymph nodes metastasis (TNM) stage, gender, depth of tumor invasion, tumor differentiation and lymph node metastasis [PMC6993749]. Through gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, ERICH3-AS1 was found to be mainly enriched in the cell cycle and apoptosis pathways [PMC6993749]. Higher levels of ERICH3-AS1 were associated with enrichment of gene sets involved in cell cycle and apoptosis pathways in GC patients [PMC6993749]. In addition to GC, ERICH3-AS1 has also been found to be highly downregulated in patients with type 2 diabetes [PMC7034863]. Further investigations are needed to validate the function and regulation between ERICH3-AS1 and related genes in GC through cell transfection assays and other experimental techniques [PMC6993749].

Genome locations

Gene Ontology annotations

Sequence

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UGUUUCCCGGACUUCUCAGAUAAACCCUCUGCAAUCUCUUGGGUUCCUUUCUCCGUUCCUUCUUUAAGAACAUUCUCAAAGCUUUCGUCUAUUGGCAUCGGCUUGGUCUCCACAUCUGCUUUUGUUAUUUCUUGGUCUUCAAUUUCAAUUUCUAAGGAUUCCUCAAUUGGAAGUGACACCUCCCCAUCCUGACUUGAUGAUUUCUUCAUGGAGCAGUGGAAAGAACGUAGUCCAGAAAUUAGAAGGUUUUGGUCCAUGGCACAGCUGAGCACUGACAACACAUCCUUCCCUGGGCUUAUUCCAUCUGAGAGGGAGAUGCACAUGUAUGAUUUCUUCUACGGUCAUUCUGAAGAUCGGUGUCAUCAAUAAUUUGGGCUUGGGACUAUCCAGUUUCACAGGGGCAUUCAGUUGAUUGAAAAUCCAAUAUCAAUAUUGUUUAUAGUAUCAAAACAAUCUACCGAUCAAAGUCUCUAAAAUUACUACAAAAACCUAUUUGAUAUCCUAUGGCAUUGCCCAAUUUAAAUUAUUUAUAAAAUAUGCAGUAAAUGUGUAUGCCAGAAAAUCAAUGUCCUAGGCAUUGACUCCUAAUUAAUUGUUUGAAAUAUUUUCAUAAUAGUGAAUGAGCACAGUGUUUGCCUGACCUCUACGAGGAAGAGGAGGAAGUAGAAGCAGAACAAAGGAAAGGAGGAAGAGGAAGAGAAAUAAGAAAGGCUGAGAGGGUUGAAAGACUUUAAGGGGGGCUAGUAAGAAAAUUGUAGGCCUCUAGAAUUGUACACAGGCCAGCCUUUCCUUCUCAUCUACUUCACUUUCCUAAAAAUCAAUUUUAAGCUAGACAAAAAAUGUGCAGAGACCAACUUUAAGUGGAUCCAAGGCAGUAAUUUGAGCUGAUUCCAUCAAAUUAUAGAUGCAUGAGAAGCAUGCAUUUUCUAAAGAAUAACAACGCUGCAACAAACAUUUUUGAAGGAACUACUAAAAUAUUUCCAUCUCUAAACUCAUCCUCUUCCACUUCAGAUGAUUUCUUUUCCAUUUCAUUCUAUUCUCUGAAGCAAAAACCAGAGGAAAGAAAUCUGAUGGAAUGAAAUUCUGCUAGCAACCAUCUGAAAGUAUAAAUGAGGGAGAAAGUCCAAGAUUUAAAAAUUCAAGCAAAUUUUCUUGCCUGUUGGAAGGAAGAGCUCUCAAAUAAAGAGAUAAUCAAGAGACAUAUUACAGGGCAUCAAGAGCCAUGAAAGUAAAUCAGCAAACUGGAUAAUUUCUUGCAGAUUAGAAACAUCUCCCUGAAUCACAGUUGAAGCAAAGGGGAUGAUGCCAGGUCUGACUCCUACUUGGAAAAUCAUAAUCCCAUGUUUCCUCUUGCCUGGGCAACUGUGGAGCUGUGACAUGCCUGUGUGCAGCCCACUGCACAAUCAGCAGACCUCAGGCAAAUCCAGCUCCAAGCUGCACCUAGCACCUUUAAUGAAGUGACUGAUUAAAUAAAAGCAUCCCCCUUUUGUUAAGCAAUACUUUCUGAAGCAGCAUGGAUUUAGAGGCAGCCCUGUGAGUUUGUAGGCGAUAAGCACUAUAUAAAUACUAGGUAAUAGUGGGAUUAGAGUCAGGGAAAGACCUGUGUCCUGUGUAUGAAAUGAGAAACUGGAAGGAGAAACUUUUAAAGAGAAAAAUACAGGAAAAGGCAGCCCUUUAUCCUUUUCAUUUCCUCUUAUUCAUAUUUCUUUCUGCUAAAGCUUAUUUCUGAUGGUAAAAUCUCUUUUCUCUUGGGUCUCAUUAUUUCAUUCUCUUUUUAAAAAAUAUUCCCUAAUUAUUGCAACCAAGUAAAUUUUUUCUAACAAACAGAAGGCCCAAGUGACAGCUCGUGAUUAAAUAUACACACUAGGAAACAAACAGUAGUUUCUUUCAAUUGACUGAACUGCCUCUAUACUUACCAUCUUGCAAAGAUAUAAUGACCAGAGACAAAUGAAACUUUAAUAAGGUUUCUCGGCCCUUUCUGCUAUCCUCAAGUAAGUAUCAAAACCUUCCAUGAAAAUUCAGUUCCAUUUGAAGAACAGGAACAAGGCCUCAUGCCCCUGCAUAACUAAAGCUCUUCUUUCUGAUUUCCUUCACCAGUUGCUUAUGACUUUCCUUCUCAUUUCUUUUCAGAUUUCUCAGGCAAGUACAACUGAGCUGAUAAAGAAACAGCAAGCCCAUUGAGUGGUUAACCCAUCAGUCAUUAUAUAUUUGCAACAUUUAGCAUUGAAUUGAUAUACUAAGUUUUCACUGAAAUCUCUUUUAUCCAUGCCCACACAAACAGUAUAGUGUCAAAGGGCCUGUUCUUGUUGAUAGUGUUGGGUAAUAACUCCUCUCCAUCUUCUUCACGAAGCCCUGGUGAAUUCUGGACAUCAAGUAGGGUGACCAUGAAAUUUAUCAUCCAAACUUGGACACAUAGUGAAAGAAGUGUUACUAAAAAUUAGGAAAUGGGGGGGAAAGGGGCAGAAUUUUGAACUAUUCCAGGAAAACUGAGAAGUAUGGUCGCCCUACGAAUUAGUCUCCCCACUUCUAGUCUGAUAUCCCUCAAAAUCUCCCUCCUGUUGGAAAUCAGAGUGAUCUAUUGUUAUUAAACAGAUCAUGUGACUCUCCUGCUUAAAGCCCUCCAGUGAUUCCCAUUAUCCAUGGGAUAAGUUCCAACAUUCCCCAGGCAACAUAAAAUGUGUUAUAUUUUCUAAUACCUACUAUCUCCCAGUGAUUGCAAUUUCUCAUGCUACAUUUAAAUGUCUGGCAACGGAACUGAUUGUAGUGGCCCAAACACUAUCAACUACUUUUAAUCUCCAGGCCUCUACAACUGUAUGAGUCACAUGAUAUUGGAACUAUUCCCUUGUAUUAUCUCUCUCUCAGUAGAUAAGGAUGACGUCCUAGUGAUCUUCAUGCCCCCAGUAACUUGCCAGUGCUGAUGCUUAGUAAGGACCUAAUUAACAUUGAUCCAACUGGACACAGACAUGGAACAAUUAGGCAUUCCAUAUUCUGUCCUUUCCAUAUUCUGAUAAAGCUACAGUAGGUUGGUUCUACCCUAUAUAGGAAGCUUGCUACAUUUAUAGAAACUCAAUAGUUACCAGAACAGGAAAACUGAUUCACAGUGUCUUGUUAAACCAAACACCAAUUUUGGUUACUAUUCCUUGAUAAAGAUUGAUACAAAACCAGCCUGACCAUAAAAAGUGGCAAUCCCCAUGUUGAUGCUGGUGGCCCUAGAGAGAGAAAGUCUGACACAAGCCAGAGGAAGAGUGUUCAUAUCCCAAAGACUUAGGAAGCAGCUGGUUGUAUGAAAACCUCACAGCACUACAUUACACAUGUUCUUCCCUUUCUCUUCUCUUUCUCUCUGGUUUUGCCUCCCAGUUUGCUUUUAGUAUAGUUACUCUUUUCAUUUUCUUUUGGGCCAUUUUUCUUACUACUGUGUAAACUUUACCUCAUGCUUAUUCCUAAUGUGCCCAGAAACACCUCAAUCCUUACAGAGGCAUCAGAGCUCUAGAUUUUCAGGAUCUCUCUCACCUGUUCCUUCCCACAGAAAUGAUAAUAAGGGUUCCUGCUCACAUUUCCUCCCCCACUCCCUCUGCUUCCUAACCUACUCUGGUGCUUCCUUGUGUAGCUCUGCAUGGUGUGGUGUAAGAGUUAUUAACAUUAUUGAAGAUGGGGUCUUGCUGUGUUGCCUAGGCUGGAGUGCAGUGGUGCAAUCAUAGUGGUGCAAUCACUACAGCCUUAAACUCCUGGGCCCAAGCCAACCUCCUGCCUCAGCCUCCUUGAUAGCUGGGAUUACAGGUGUUAGAGAUUGGGUCUUGUAUGUUGGCCAGUCUGGUAUCAAACUCCUGACCUCAAGUGAUCCUCUUGCCUCAGCCUUUCAAGUCACUAGGAUUACAGAUGUGAGCCACUGCACCUGAUCUUGUGAUGGUUAAUUUUACCUAUUAAUUUAGCCGGACUCCAAUGCCCAGAUUGGUAAACAUUAUUCUGGAUGGAUCCCUGACCAAUGCAUGUGGUGUGUCCCCUCCUCUUGGGAACUGUGAGUAACAAUCUAUCUUUUUGAUGGCAAUUGUCUCUUAAUCUGUAAGUUUCACCAUACCUGAAUAAUUUUUAAAAACCCACAUUUUAAAAUAGCCAUGCAGAACAAUAUACCUACUUUCAUUAAGAAAGGGCCAACUAGUGAAGGUUUCAAGCAGUAGAGGAGCAUGUUGAGAGUUUUUCCAUAAAGUUUAAUUUAGCACCAUUAUGUAGAAUCUAAUAAAACCGAGAUGAAUUUUGCUUAUUCCUUUUUCCCCUUUCUGCUUUUCAAUCUCAGUUCCCUGGUUCUAUCUGCUAACUUCCUACUGAUCAUUCAAAGCCCAUUUCAAAUGCCACCUUCUCUAGGAGGCAUUCUCUAAUCUCCUCGGUCAAAACUAAUAUUUCUUUCCUCUAUGUUUCUAUUGUGCUUUAUUUAUAUCACAAUUAUAGUACUCAUCACAAUAUAUCAUGGUUAAUUGUAUAUAUAUAUAUCUGUCUCUCUUGCUAGACUGCAGUCUUUCUGAGAGAAACAGUUUAGUCUUACCCAUCUUGGUAACCUCAGGACCUAGCAUAUCAUUUGCCAUUAUCAACAAAAACUGGACUGAGCUAUAUUCUCAUUUAGAGGCAGGACAAGUAUAUAGAUGAUUGCAAUAGUUCCAUUAAAAGAUUAGUUAUCAAGCCCCUGAACUAGAGAUGUAGCAGUAAGGAUGAAAAAGGAUUAUCAGGUACAUGAGCCACUGUUCAGGUGGCAUCUAGAGCUGUGCCAUCCAGGACAGCAGCCACUUCUCCCAUUUGGAUGCUGGGCAUUUGAAAGGUAGCUCAUUUGCUGUAAGUAUAAAAUAUUCAUUGAAUAUCAAAGACAUAGUAUAAGAAAAUACAUCAUACUUAAUUAAAAUUUUUCAUAUUGAUUACAGGUGGAAAUGAUAUUUUAGAUAUACUUGAUUAAAUAAAAUAUAUUAAAGUCUUAAAAUUUA

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