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Homo sapiens (human) long intergenic non-protein coding RNA 707 (LINC00707) URS000075C99D_9606

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LINC00707: LINC00707 is a long non-coding RNA (lncRNA) that has been studied in various cancer types. In cervical cancer, the knockdown of LINC00707 using siRNA was found to significantly enhance apoptosis in cervical cancer cells [PMC8261168]. Similarly, in osteosarcoma cells, the knockdown of LINC00707 using siRNA resulted in decreased expression levels of LINC00707 [PMC8285991]. In a study involving NOD/SCID mice, it was observed that LINC00707-modified bone marrow mesenchymal stem cells (BMSCs) promoted ectopic bone formation [PMC9150698]. Additionally, the inhibition of LINC00707 reversed the promotion of osteogenesis-related gene expression induced by miR-103a-3p overexpression [PMC7387089]. In glioma cells, it was found that LINC00707 promoted cell proliferation, migration, and invasion by acting as a sponge for miR-613 [PMC7607719]. Furthermore, silencing LINC00707 was shown to suppress cell proliferation, migration, and invasion by inhibiting AHSA1 expression [PMC8285991]. Overall, these findings suggest that LINC00707 plays a role in various cellular processes and has implications for cancer progression and bone formation.

Genome locations

Gene Ontology annotations

Sequence

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AAAAUAAAGCAGGCAGAGGAACGUGGAAGGACUAGACUGCCUGAGUCUUCUGACCUUCAUCUUUCCCCUGUGUUGGAUGCCUCCUGCCCUCAAACAUCAGACUCCAGGUUCUUCAGCUUUUGGACUCUUGGACCUACCCCCCGAGUGGUUUGCCAGGGGCUCUCAGGCCUUCGGCUACAGACUGAGGGCUGCAUUAUCAGCUUUCCUACUUUUGAGGUUUUGGGACUUUACUGGCUUUCUUGCUCCUCAACUUGCAGAUGGCCUGUUGUGGGACCUCACCUUGUGAUCAUGUACAUGAGGGAAAUACACACCCCUCCCAGGGAUGAUGGAAGGUUAAGGUCCUAACACCUCCUGCACAUCUGAGCAGCUGCACAUUGAACCAGAUAGUCCUGGAAUGUGGGAAAACAGAGGCAGACUCAAGAGUCUGGAACAUUAUUUUAGGAUCACACAAAAAAGAUACAUAAUUUUCAUAGAAUGAUACUGAAAGCAUCUCAAAAAUAAAAUCACGAGUAUCUGCAGAUCACUAUGAGACUGGACUGGAACAUUACCUUCAGACACAUUGAUAUGACUACAUGCUGGACAUUUUCUUGCGGAAAUCCAAAAGAAAUCCCCAUUUUCUUGCAGAAAUCUAAAAUAAUCUCCCCUAUGUGCAAGUCAGACUGAGCACCACUCCCAAGACCAUGACCUCCCCUGCAGCCCUGCUCCUUCCCACUCACCUCUCCUCUUGAGAAAGCCACCUCCCACCACCCAGUCUGCAGUGCCAGAAAACUGGAAACCAGCCCCUAAGCUGCUUUCACCUUCGGCCCAUUUCUCACUAGCCAGCCUCUCCCACGGCCUCCCCAGUUUCUUCAAAUACACCCCCUCCACUAUUCACCAUACUGCCACCGUGAUUUAUUUACAACUUUUUGUCCGGAUUACCUCAGUAGCCUUCUAAUUGUCCCCUUUGCAUCUAAAGUAGCCCCUCUCAUCCCCCAAAUCUUACGUCACUCUUCUACAUAAUUCUGGCUUUCCAUGACCCAUAAACCACAUUUCUCAAGUGUGCUCUAUGCUGGCUUGAAUAUGUUAAUAAUCUUAAUUCUACUUUUAGUGCAAUUUUCUUAGAGCUGGCAUCACUUUCAUCAUGACGUGAGAACUUACUAGAGAUAGGCAAUGAUGACUCACAGUCAAGCCACAUGUCAUAUGCUGCAGACAUCUGGACUGCUGCUUAUUUGCAAAUCCUUUUCUUCAUAUUUUUCUCAUUUGUAGCACUGGAUCAAUUCCAAUUAAGAGUUUAAUAAUGAAUUAACUAAUGAUUUAAACAGGUGGAUAAGACUAACACUGAACCAAUGAUUUUAAGUAAAUCUAAAUACAUAAAUCCCCCCAAAUUAUUAAUCUAUGUUGUUUACUAAGAAGUGUAUUAAAAUGAUAUUGAAAAAGUUUGCUUUGGGAAAGAGCUAGAAGUUAGAAGGUCUAGGUUCAAAUCCCGCCUCUACUCCAUCCUUGACUAAGAUGUUGGACCCAUCACCUCAACUUUCCUUGGGUCUUUUUGCCCAGACAUGACCCGAUGACACAGAGCUUACCUGGACCUCCACAAUAGUAAAUAGAACAGGGCCAGCAAACCAAAAUUUGUUGAGUCCUUUAGAAUUAAGUAGCUUAGAUAAAUUUUCAUCAAAAUCUUUAUAUAGUAGGGAAUAGAAAAAAGUCAAUUCUGUUUUAUUUGAGGAUGUAUGAAUAUGUUACCAUUUUUCAGACUCUGAUUUACCUUCCAAUUAUUGUUUAUUGGGGUCAUUGUAAAUUAGUUAUCAUUUUUUGAAUACACAUUCACUGCUGACAAAGUGGUGAAGCCAGAAGUUAUGUUUGACCAGGGAAGAUUAUGACCCUCAAAGGAGAAAAAUUCACAGGGGGUAGUUGAUUAUUGGUGGAAUGGAGUGAGAGUGAAUUCCUUAAAAGUUUAAACGAAAGCAGAACUAUAUUCAUAUCAUGGAGGGAACUUAGUUUCUAAUAUGAUGAACUAUUGCCCCAAGUCAUGACAAUACCUUGCUCUCUGGAAGAGAAUGAGUGAGUUUUUCAUCCGCCAAGAUACACACUCUAUAUUUCCAACCAUCACAUCUGCCUUGCAGGCUGACUGAACCCAGAGCAAAUCAAUCACAAAAGUUAAUCCAAAAGACUUCCCUUCAGCUGCUGGAAAUCAGUCAUCACAUCUGUGAAAAGAGUGCUAGUUAUAACAAAUGAGAUCACAAAUUUGACCAUUUUAUUAGACACCCUCUAUUAGUGUUAACAGACAAAGAUGAAGGUUAAGUUGAAAUCAAAUUGAAAUCUUCUUCCCUCUGUACAGAUUGCAAUAUCUGAUAAUACCCUCAACUUUCUUGGUGCAAAUUAAUUGCCUGGUACUCACAGUCCAGUGUUAACAGGCAAUAAUGGUGUGAUUCCAGAGGAGAGUACUAGGUGGCAGGAAAAUAAAUGAGAUUAGCAGUAUUUGACUUGGAGCCAUAGGCAUCAAUUCUGCUCCAGCUGUCGACCAGGUUCUAAAAACAAGACUCGGAGCAGCUUUUGCUCUUGCUAGUGAUGCAGGGCCAGGAGAGCCCCCACACUCUGCAUUUGCAGGUGUCCAUGAGGGGAAGCCACUCCUGCAUUUAUCCUGUGAGUGGAGAAGCUCAGAGGAAUGAGGACAUUCCAACAGGGUAUCAGAAUUCUCUUUUGUUUAUGCUAAUUGACAGCAGGAACAUCACCAUCUUGGACAAACACCACCAUUUUAAGUUCUCUUUUAUUUAAAAACUGCCUAAAUCCAGCCCCAAAACAUCAGCCUAAUGGCUAUUGUCAGCAUAAUCAGAAACAUUCCAACCCUAAGAUAAACACCCCUCUGGCCAGAAAUAUGCCGACCCCGAGACAGCCUCCCCUCCGACCAGAGACAUUCCAAACCCGCAGUAAACUUUCCUUCACAUGGAAACAUUCCAAACCUACAAAAAGCUUCCCUCUUCCUAAACCCUUAAAUAUCCUUAGUCUGCAAGAGAGAAUGCUCCUGACUGAAAUCAGCCAGAAGCCCCUCUCAGGUUUAUUCUCCAAAAUAAACCUGUCUUUGACUGUUGAGCCAAAAAAAAAAAAAAAAAA

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Publications