MIR508: MIR508 is a microRNA that is expressed in rice and has been found to confer enhanced tolerance to salt stress and nitrogen starvation in creeping bentgrass. This is achieved through the modification of the transcription of AsAAO and COPPER ION BINDING PROTEIN1 (AsCBP1), which are involved in salt response and nitrogen starvation adaptation, respectively [PMC5916090]. The miRNA-mediated salt response is primarily achieved by influencing various factors such as water retention, cell membrane integrity, chlorophyll content, cellular potassium homeostasis, as well as the activity of CATALASE (CAT) and ASCORBIC ACID OXIDASE (AAO) [PMC5916090]. On the other hand, miRNA-modulated nitrogen starvation adaptation involves regulating biomass production, nitrogen accumulation, chlorophyll synthesis, and NITRITE REDUCTASE (NiR) activity [PMC5916090]. MIR508 has been found to be part of a cluster of miRNAs known as the "fragile-X miRNA (FX-MIR)" cluster. This cluster includes miR506, MIR508, miR509-1, miR509-3, and miR510 [PMC9130735]. The expression pattern of MIR508 has been observed in various parts of wheat plants such as stems and internodes but not in leaves or roots [PMC2394755]. Additionally, the expression levels of MIR508 were validated through semi-quantitative RT-PCR analysis [PMC2394755]. Overall, MIR508 plays a crucial role in conferring tolerance to salt stress and nitrogen starvation by regulating specific genes involved in these processes. Its expression pattern suggests its importance in plant development and stress response.