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Homo sapiens (human) HPN antisense RNA 1 (HPN-AS1) URS000075C3F8_9606

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HPN-AS1: HPN-AS1 is a pyroptosis-related long non-coding RNA (lncRNA) that has been studied in various cancers, including hepatocellular carcinoma (HCC), prostate cancer, osteosarcoma, colon cancer, and ovarian cancer [PMC9857215] [PMC8456090] [PMC9263208]. In HCC, HPN-AS1 has been identified as a hub differentially expressed lncRNA and is associated with the prognosis of HCC patients [PMC8456090]. Additionally, HPN-AS1 has been found to be upregulated in HCC tissues compared to normal tissues [PMC9263208]. In prostate cancer, HPN-AS1 has been implicated in the diagnosis of the disease [PMC8456090]. Furthermore, HPN-AS1 is one of the five pyroptosis-related lncRNAs that can be used to develop prognostic models for ferroptosis and tumor mutation burden in HCC patients [PMC9263208] [PMC9857529]. In breast cancer patients, high expression of HPN-AS1 is associated with better overall survival [PMC8253500]. However, the function of HPN-AS1 and its relation to lipid regulation are still unclear and require further investigation [PMC5417062]. Moreover, in hormone-related cancers such as prostate cancer (PRAD), breast cancer (BRCA), and kidney renal clear cell carcinoma (KIRC), HPN-AS1 expression levels are significantly correlated with overall survival and can serve as a biomarker for prognosis in these cancers [PMC7557915].

Genome locations

Gene Ontology annotations

Sequence

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GUAAUUGCUGCGGGGAGGACAGGCCAGCUCUGGAAGAAAACAGGUGGACCUGGGUCCCAUUAACCUGGACAGACACCUCCAAGAUGAGCAUGAGGGGGCUGCUGGAUCUGUUCUCCUUUCACAGCUGUAUCCUGAAGAAUGGCAGUGAGCCGGAAGAGCCACAGGAUUCGGCAAAGACGGACACACAGAAAUGGGUUCUCACUACGUUGCCCAGGCUGGUCUGGAACUCCUAGACUCAAGCGAUCCUCCCACCUCAGCCUCCCAAAGCACUGGGAUUACAGACAUGAGCCACCGCACCCGGUCAGGUGCAGCCGUUGGGGACUGCAAAGCUGUUGAUGCAGAAGGCCUAGUGCCUGGGGAUGCCCACAUUGCUGGUGUCUGCCACAUUCAGGAUGCCUGAGGUCCGGGAGCCAGGAAGGGUGAAGUAGUCCCUCUGUCGGCCGCUGUUGAAGCCUGCCUGGGGGUGUCAUUUGGAACAGGGUCAGCCCACCUGCGUCCUCACCCUCCCCAAGGACCCAGGGAGGCCCCUGUGGGUUCCCCACUCACCUGGGCCGCAAUGCCCCCCAGGCCGUGGUGGGGGCUCCCACCGCUGGCCACCCCCAUGGUCCACUGGAUGUCCUUGUGGUGAAACAGCACCCAGGAGGGGCCGCUGCCCAGGGCCAGCACCUCCUGGAAGGUGUUCACCUGCAGGGCAAGCGCCAGGAGCCAGGGUGUCGUGGGCUGGUCCAGGGGCACCCAGGACCCUCCUCACUGCCCAGUCCUCAACCGAGCUCCAUCUGCACCACUAAGCUGGCUGCUUCCAGCUGUGCCACCUCCUGGGCCCCCAUCCACACCACAUCCCGGGCCCCUACCCAUGCCACAUCCCAGACCCCCAUCCACGCCACCUCCCAGGCCCCUGUCCACACCAUGUCCACAGCUGCCUCUGCUGGCACCUGUGCCAGCCUUCCUUUCACAUCCCCCAGUCUCGAUUUUUCUGCUCUGCUCUCAUCCCCUCUCUCUCUCCGUCUCUCUCCUUUUCCUAUUCUCUGUCUCUCCAUCUGAUCAUCUCACUCCUCUCGCUUGCUGUCUUGCCUCCUCUCUCUCGCCAUUUCUCUCCCUGUUCGUGUCUUCCCUCUUUCUCACCCAUUUUCUCUACCUCGCUGCAUCUCCAUGCUUCCGUCUCUCUGUCUCUCUCUUCCCGCCCCCUCUAUCUCUCCCUCGUUCCCCCAUCUCCGUCUCUCCUCCGUGGUGUCUCCUCCUUACCCAGGAAUCCAAGCCCUUCUUCCCAAGGGGUUGGGCCAAACAGCCUCAGCCUGGGCCCUUCUCUGCCACCCGCUUCCUCACCUGGGGACCAAGUGCCCCGUAAAAUGGAAUUUGGUCCCACAUGGCCACCAGCAGGGCGCAAGGGGUGGGCGGGGCAUGGGGGAAGGCUGAGGCCAGGUCUCAGGCCACCUGCUGCGGCAGCUCUGGCUGGCGGCUCUGCCGGUACCACAUCUGGCCCCUGCUCAGUGUGGACCCAUUGGCCCAGAACGGGACUGCGAAGGCCUGGCCCAUCUCCUGGGGAAAUGCCUCCAGUGUGAAGAGAGCCACAGGCUCCCCGAAGGACACCAGCCCAUUGGUGCAGAACUGGGGGAAGUGAGGAAGGGCAAGACCCGCAGGGGGGUGUUGGCAGGGCAGGGGACAGAAGAGGGACAGGGCCCGCCCCAGGAAGACAGAGGACGAAGCCAGAAGGAGCCAGGAGCUAUAGAUAUAGACAGGCUCCGAGUCAAGAGUGGGGUGGGGAGAAGAGAGAGAGCCCAGGGACCGCACGGUCAGGGCCAGGGCACUCACAUAGGCCGUCCCGUGUGUGGCUUCAAAGAGCAUGAAGGGCUCCAGCAGCCGCAGCUCCUCAGAGAAGUCAUCAUCCUCUGCAGGGAGGGCCUGAUCCCCACACUCCAGCCCAUAGGGGUACAGGAGCGAGGCUGGGGACACGAGACCACUGAGGCUCCCCUCAGAGCCCCAGGGCAGGGCUGUGUCCCCUCAGUCCCCAAGAGAAAGCUCCAGGUCCCCUGAGGGACUCCAGGGUGGGGCCAUGGCUCCUCAGACCCCUGGAGCCCUCCCUGCCUGUCCACAUGGCCCUGUCCUCUCUCCAGGUUAGGGAGCACAUCCAUUCUCACCUCUGAUCUCCUUGCUCCAAGUCACUUGGUUCUGUAGGACUGAGGGGAAGGAUGUCAGCUAAGGGCUGGGGCCCACGUGGCACAGUCGACCCCCUUCCAGAGUCCCCACUCCUACUCACCCACCAGCAGAAGCCACAGUAUCCCCAUGGUGGCUGCAGGUGCUGCGGGCCAGGCGGGCUUAUACCAGGGCAGAGGUGGGGCCAGGGUGGGGACGGGGCAGCUGGAGCUCACCUUCCAUUGUUCGAGGGUCCAGGGGGCCUGGGGGUCUCCCAGGGAUCCUGGUUCCCAUCCGGUCUGCCUGAGGCUGGGCCAGGUCUGGGGUUGGUGGGCAGGGCAAGGGAGGAAAGAGGGGAUGGAAAUCUUCCAGGGCUUUCCCAGGGGGCCGGGUUGCCAGACCCUGGAGGAACCCCCCACCCAUUAGCAGGGCUGGGCACAAGUCAAGCGAUCCACAGUGGGAAAGUUGAGCCACUGCUUGGUGAAGGGCCGCUGCUGACAGACAGCUGAACAUGCAGGGAGCCUCUUCCCAUGGGGCCCUGCUGGUUCUCUUGGAGCAGGUUAGAGAUGAGCACACAGCAUCCAGGAACGGAGUGCAUGUGCAUCAAGCAGGGCCAAGAUGUGUGGCUGGGGAGACUCGUGGGCUGCUGGCCAGCCCCGGGGGCCCAGGGGUGGGCAUCUGCAGGGCAUGGCUGGGGCUGCCAUGGUGGAUAGUCAAGGUCAGGCAUUUAGGAGUGUUACUGGACCCAGAAGGGGAGAUUCGCCUGGAGACGUGAACGGGGAGACGGGGAGGAGGAGCAUACAGGCAAGGGGGCUCGUUACUGUGCACCUGUGAGAUUCACGGACCACCCUGGUGGAGGAGGCUCAGAGUUAGGCACUGGGGACUCCAUCUUCAAAGCAGUGUCCCAAAGGGGUGCUCCAGACCCUCAAACCCCAGACAGCCCUUUACCUGGUCAAACCACAUGGGACAGAGGGUCACCUGUGUUCCUGGACCAAACUGAGGAUUAGGCUGCUAUUUCUCAUGGCCCAGUGAUGAGAUGCAGAUAAACUGGGAGAACAGGGAGGUUUUUUUUGUUUUUGUUUUUGUUUUUGUUUUUGUUUUUUGAGACGGAGUCUCGCCCUAUCGCCCAGGCUGGAGUGCAAUGGCACUGUCUCGGCUCACGGCAACCUCUGCCUCCCGGGUUCAAGCAAUUCUCCUGCCUCAGCCUCCCAAGUAGUUGGGAUUACCAACACCCACCACCAUGCCUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGGGUUUCUCCAUGUUGGUCAGGCUUGUCUCGAAUUCCUGACCUCAGGUGAUCCGCCUACCUCGGCCUCCCAAAGUGCUGGGAUUACAGGCAUGAGCCACCGCACCCAGCGAAAAGGGAGUUUUUAUUUCUGUAACUGGUUAUAGGGUGAAAGCCUGGAAAUUGUCCCCAGACCAACUCAAAAUUACAAAGUUUUCCAGAGCUUAUAUACCUUCUAAGCUAUAUGCCUGUGUGUAAGUGUAGUUUCUUCAGACCCCCAAUUAAACUUGUUUAAUCCU

Taxonomic tree

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Publications