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Homo sapiens (human) gastric cancer associated transcript 2 (GACAT2) URS000075C3BF_9606

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GACAT2: GACAT2 is a type of RNA molecule that has been found to play a role in regulating the cementoblastic differentiation of cells by binding to PKM1/2 and affecting mitochondrial function [PMC8927299]. Research has shown that GACAT2 overexpression can lead to the translocation of PKM2 into the mitochondria [PMC8927299]. This finding was supported by subcellular fractionation analysis and immunofluorescence staining for mitochondria and PKM2 in PDLSCs [PMC8927299]. Furthermore, the expression of GACAT2 has been found to be associated with certain clinicopathologic features, such as lymphatic metastasis, distal metastasis, and perineural invasion, in patients with gastric cancer (GC) [PMC6580350]. This suggests that GACAT2 may have potential as a tumor marker for predicting the prognosis of GC patients [PMC6580350].

Genome locations

Gene Ontology annotations

Sequence

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ACAAUAAAUAAAACAGUUGGUGUCAAUACAACUCCCCUUAUUUUCUCUCAAGUCACCUGGAUCGUCCUGACCCCGGGAACCCCGUCUGCAGCACCAGGCCCCCUCCGUGGAGAAAAGAUGGAGCCGGAUUAAGCACCCAGUGCUAAGGCGACUAAGACGCCACUGCCCGCAGGCCCUGCCGGAAAAUACUCAGAGAGUGCAGCAGGCGCCGCGAUUCCUUAGAAAGUGCUGGCGUGGCCUCUCCUGACACAGAAAGCCGGCUCCUGGAUGCUUACAAAGGACUGGCCCGCGCAACACCGUUGCUCCUCAACCCGGGCCACACUCCAAGGACCUCUACUGAGCUUCAGCUUGCUCACCGAAAACGGCGCGGCCCCCUCUACCCGGGAUGUCGGAGCCCAGGAGACCCUGAGAGCCCCCAGCUCUUUCCGUAAUUGCAGGAGAAGGGGCAAGCGGGUCCGUAGCCGGGGGCCCUCCAGUGGCAUUAUCCUGAACCGCCACGCCCGCACGUGGCCCGGCUAGAGCUCCCUGGCGAAGGAUCACCUGUUCCUACAGUGACAACUGGACCUGGCCCGAACCCCUGGCAUCUGGCAACAUUAUUACCUGUCGAAACAGAAGUAGAGAUUUGAAAUAGAGGAUGCCUGUUCCCAUUUCCUCCUGCUGUCUGGAAGGAAGUCUGGCUUUCCAGCCCAACUCUAAGCUCAUCUUUACAUACAAAAUAAGGGUAUGUUUACAUGGAAAGCAAAAAUAGAACCAUGGAUUUACAGAAGGUUCCAUAGCAGCAAAUAACAGUGCUUAUGAAAUAAACAUUUUAAAUAUUAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications