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mmu-mir-499: Mmu-mir-499 is a type of microRNA that has been studied in various contexts. In a study on uterine miR-499 expression, it was found that intervention with synthetic antagomiR-499 led to a decrease in miR-499 expression and an increase in the expression of the mmu-mir-499 target Lin28B [PMC5999645]. Exosomes isolated from peripheral blood plasma of mice during early pregnancy showed higher expression of mmu-mir-499 compared to non-pregnant exosomes [PMC5999645]. Inhibition of mmu-mir-499 was found to increase the risk of embryo loss and disrupt the balance of inflammation at the maternal-fetal interface, leading to an increased risk of pregnancy failure [PMC5999645]. MiRNA sequencing analysis revealed that mmu-mir-499 is regulated by Esrrb and is involved in early pregnancy [PMC9149258]. Additionally, lower levels of mmu-mir-499 have been associated with an increased risk of bovine pregnancy loss [PMC10036776]. Mmu-miR-208 and mmu-mir-499 are encoded by mouse Myh7 and Myh7b genes, respectively [PMC4410957]. Mmu-mir-1, mmu-miR-133a, mmu-miR208a, and mmu-mir-499 have been found to promote cardiac reprogramming in mouse fibroblasts into induced cardiac myocytes (iCMs) [PMC8946776]. The existence of pir5 was annotated as mmu-mir 49 9 in whole mouse embryos [PMC1874652]. Real-time PCR analysis has been used to quantify mature mir 49 9 levels in various studies [PMC4659612] [PMC8885328].
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