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Homo sapiens (human) ARHGEF26 antisense RNA 1 (ARHGEF26-AS1) URS000075C1F4_9606

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ARHGEF26-AS1: ARHGEF26-AS1 is a long non-coding RNA (lncRNA) that has been implicated in various processes in cancer through the competing endogenous RNA (ceRNA) network [PMC8739919]. However, the specific mechanism by which ARHGEF26-AS1 regulates cancer development has not been experimentally confirmed [PMC8739919]. Recent research using luciferase reporter assays has provided evidence that ARHGEF26-AS1 can upregulate the expression of ADAM23 by competitively binding to miR-372-3p [PMC8739919]. This suggests that ARHGEF26-AS1 may function as a ceRNA, sequestering miR-372-3p and thereby relieving its inhibitory effect on ADAM23 expression [PMC8739919]. However, further experimental validation is needed to fully understand the role of ARHGEF26-AS1 in cancer development and its potential as a therapeutic target [PMC8739919].

Genome locations

Gene Ontology annotations

Sequence

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UUUUGGGGCUAGAAGUUGCGGACUAGUAGCUGAGGCGGCACGGGAGUGUAGGCGCGCGGGGUCGUUGCCGGGGGCACAGAGUGAGAACAAGCAAGGGAGCCCUGCUGAAUUGCAGCUUAGGAAGCCCUGAAUCCUGGAGAUAUGUUCCUGACCCUUCCUUCUUGAAGGGACAGCUGUGUAACCAUUCAACCAUCUGGCCAUCAGUUUCCACAUCUGUGAAAUCAACUUCUGCCUCAUGGAGCCGUGAGUUCCCAAGUGAAGGCAGUGAGGGGCUGUGGUGUGAUCCAGGAGGCUGAGAAUUAUGCAGUGGGUGCUGUCACCUUGAAGACAUCAGCGUGAUCAGGCAGAUCAUCAUGGUACUGCAUUUCCUGGACACGAUCUUAAUUUUCUUAAUACCUCCACCGACAUUUCAAAUAGCGUCUCUAAUGCCCCAGAGACUUUUAUGCCCCUAAGGUAGUUUUCUUUCUUUUGUGAAGCAGAAGAAGGGAAAUUGUUAAAGGGAAUAUUUUAACUAAAUUUAUUUCCAUAAAACUAUCUUUGUCUUUAUAUCUCAUGGAAAGUGUUAGGUAGCCUCAGGAUUAUAUCUCCGUUGGAAAACUGUAGAUGUAAACCUUCUUGCUAUCUACAUACUUACAUAUUUUUCUGUUGUUAUUUACUUAUGAAUAGCAUUUUGAUUAUAGCAGAAAUAAAAUACAUUAAAUGACUAAGCUCAGAAAUAAGAAAAAAAGGUCAAUGGUGAUCAUUUAUUUGGAAACUAUGAUAUUUUAAUGAUAUUAAUGGUGUAAUUGACAUUUAGUUAAACAUAUUUCAUCGUAAGUAGAGCACUUUAACUCUUACGGUCCACUUAAAAUGUAAUCAUACGUUUAUGUAUUUCUAGUUAAUGUAUCAAACUCAACUGAGUAAUCAAUGUACAUCAUUUAUUUUGCUCCUAAGUUAAUACACUAAGUUAUGCUUUAAAAUUACUAAUUUGCUGCAAUAUCCAAUACUCUCUUUUAAGUCUUACGUCUGCAGAAAAGGAUAUAAACAUUUCAUGACACCAAACCCAAGUAUUUUUGAUGCCCUUGGCAGUGUCAGUUGAACAGACAGUGUCAUUUAAUGUUUGAGACAGCAUCUGAAUUCCUUUUAUUCUUAAAAUUCUAUUUUAAAAUGCAGUUUUUGGAAAGUUAAUGUGAAUAGAAAAAUUUCUAACAUUUUAUGUGCAUGUGUUUUGUUUGUUACAGGCUUAGCAUCUCAAAUCUGAAAAUUCGAAAUCUGAAAUGUUUCUAAAAUUCAACUCUUUUGAGUGCUGAUAUGACUUUCAAAGGAAAAGCUCAUUGGAGCAUUUCAGAUUUUGGAUUUUUGGAUUUGGGAUGUUUAACCAGGGUAAAAUAUAGAAUGCAAAUAUUCCAAAAUCUGAAUAAAAUUGAAAUCUGAAAUGCUUAUGGUUCCAAGCAUUUUGGAUAAGGGAUAAUUAAGCUGUAUAACUUAUAAAACUGAAUAUAACAAAAUUUCCCAACAUGUGGAAAAUGAUGUCUUUUUUCAAAAAUGUCAAUAGCAGAUACAUGGUACAGUAAGUUAGGGGAAAAAAUGAGGUUUCAUAUCUUCUAGUUUCCUAAUUAAAAGGAGCCCAUUCUGGGUUGGAAGAAAGUGUCAGUAAGAUCAUUUCUCCUAUUUGAAAAUCAUACAAAGCUUGUCAGAGUGACUCAGGCCAGGAGUGUAGCUGGGCGUGUAGCUAAAUGAUAUCUCCCCACAUCUAUAUAAUAAGCUGUUACCUGCUUUAAAAGGAAAAGCUCUCAGCAUGACUCUAAUGUUGCAUUUCUGGAAUACAGCUUGAAAAGCUCUUCUCAGGGUUGAACAGAGCAUGAAGGUAAUGGUUAUUAUCUACUCACAUUAAAAAAAAAAAAAAAGAAAGAAACCACCACAGAAAACUACUUACUGUCUUUAGGCUCUACUUUCAAAAGUGCCCUUUAUGAACGCUUUUACACUGUUGAUGGGAGUGUAAAUUAGUUCAACCAUUGUGGAAGACAGUGUGGUGAUUCCUCAAGGAUCUAGAAUCAGAAAUACCAUUUGACCCAGCAAUCCCAUUACUGGGUAUAUACCCAAAGGAUUAUAAAUCAUUCUAUUAUAAAGACACAUGCACACGUAUGUUUAUUGCAGCACUGUUCACAAUAGCAAAGACUUGGAACCAACCCAAAUGCCCAUCAAUGAUAGACUGGAUAAAGAAAUUGUGGCACAUACACACCAUGGAAUACUAUGCAGCCAUAAUAAAAGAUGAGUUCAUGUCCUUUGCAAGGACAUGGACAAAGCUGGAAACCAUCAUUCUCAGCAAACAAGAACAGAAAAUCAAACACUGCAUGUUCUCAGUCUAAGUGGGAGCUGAACAAUGAGAAAACAUGGACACAGAGAGGGGAACAUCACACACUGGGCCUGUUGGGGGGUAGGGGGCUAGGGGAGGGAUAGCAUUAGGAGAAAUACCUAAUGUAAAUGACAGGUUAAUGGGUGCAGCAAACCACCAUGGCAUGUGUAUACCUAUGUAACAAACCUGCAUGUUCUGCACAUGUAUCCCAGAACUUAAAGUAUAAAUAAAUAAAUGAAUAAAUAAAUAAAUUUUAAAAAGUG

Taxonomic tree

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Publications