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Homo sapiens (human) ATP13A4 antisense RNA 1 (ATP13A4-AS1) URS000075C044_9606

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ATP13A4-AS1: ATP13A4-AS1 is an antisense long noncoding RNA (lncRNA) derived from ATP13A4 [PMC8131847]. Its function in cancer is currently unknown [PMC8131847]. Lower levels of ATP13A4-AS1 have been associated with poor patient outcome in lung adenocarcinoma (LUAD) [PMC8131847]. It has been suggested that ATP13A4-AS1 may play a role in the progression of lung cancer by exerting similar impacts on cellular activities as the genes AGER and ANGPTL7, which are strongly linked to cancer [PMC8131847]. A study has revealed the roles of ATP13A4-AS1 in carcinogenesis, providing experimental clues for further investigations [PMC8131847]. Additionally, ATP13A4-AS1 has been identified as one of the genes included in a prognostic signature for epithelial-mesenchymal transition (EMT)-related long noncoding RNAs (lncRNAs) associated with patient outcome [PMC9428519]. It has also been found to be differentially expressed between different clusters and associated with genomic instability [PMC8585518] [PMC8928224]. However, further research is needed to determine whether the expression of ATP13A4-AS1 is directly associated with genomic instability and its specific role in cancer progression remains unknown.

Genome locations

Gene Ontology annotations

Sequence

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GAGAGAGAAAAAAAAUGUUUCAGAGGAAGGAGCCCCUGCCUUCUGGUGAAGAGUAUUCAAGAUGAAGAUAAACUUUUCAACUUAAUAUCGAGACUUUGAUAGCAGAAGGGAUCUACUCUUGAAAGUCCAAAAAAUGUUGUUGCUAUAGGAACAGACUCGGUGAACAAGACAUUUGAGAAGAGAAGGUCAAAGACCCAGCUGCACUUCUGCUUCACUGCUGAACUUCUGCUUCUUCCUAUCAGGGAAUACACUGCUCCUCACAUUAGGGAUUUCCUAAAAUUGUUAGGUGUUUUGAACAGAACUGGCUAUACCAAUGAGGCUCAAACAAGAAUCAUAAAGUGCAUGGUGCUUCUCUCCCUCUCUGUUUUCUUUAAAAAGAAAACAUUCUUGACAAGAUGAAUACAAUAUUUUCAUUCUAGCAAAUUUCUGCUGUCAGAGGUUAUAUUUACAGGAUAGAGAGAUUUCUCAAACAUGACCUUUUCUCGUGUAAUACCAGAGUGAAAUUUUAGAAAAGUCUGUGUGUGUGUGAUGCGUGCGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUCUCGCAGGCUGAGAAGUGGGAUGGGAAGAAGGGAAUGUGGCUAGAAUCUUACCAUCUCAUUCUCUUCUCCUUCAUUGAGCAGAGCGUGCUGGCCCUUCUCAAAGUGUCCCAUGAAAAAGUUAUUCCACACCUCCUCCCUGACCUUGUCGUGCAGACGCUUCCAGGAUGAACUCCAACUCGCCGAGCCACCGCAGCUCCUCAGCUGACUAAAAGAGUUAAUGAUCCUCCAGGUUAAAACUCCUCCUUGAGCACACACCUUCUCUCAACAAAUGACAAUACUUGGCAAACUGAACUCCUCCCACGAGUCGCCCUCUGCUAGGAGGAAUUGCUGGCUGCUCCCUGCUUAUUGCAUUCUCUCAGAGCAGCUGUCUCAAAGGAGGCUGCUCCCAUGCCGAUCUUUUUGUGCCCAACUUACAGGGAAAGAACUCAUUGCCUGCCCAGUGCCUGCCAGCCUCAGACUUCUGACUGCAAAUCCAACAGGACAAUACAGAGUUGGCAGGACCCUUCUCAGGAGUGAGGAGCGGGUGCAAGAACUCCCAGGUCACUGCUUUAUUCAGAGGACCUAAGGAAUUGGGUUGAGCGGAAGCGCACAGAGCUGCAGAUUUUCUUUGAUGAAUGAAAGCUUCAAUCCACAGGUUUCUAAUAGUACUCUCAUUCAUUUUGCUUACAAAAGGUACAGAUUAUCACUAAUCCUCUUCAAAAGGUAUUUGUAAUCACAUUUCCUUGUAUAUGCAAAAAAAAUUCUAUUUAAAGUGUAUGUGAAAUUAAGUUUACUUUUUUGAAACACAUGUAGAAAAAGAACAAAGGUAUCAUCAAACUAGUCUAUGUAGUCUCCUUUCACUAAAAUAUUGAUGGUUCAACACUUAAGGAAGUCUAGAAAUAAAAUAUUCAAAUGAC

Taxonomic tree

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Publications