v24

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Homo sapiens (human) RAD51 antisense RNA 1 (RAD51-AS1) URS000075BE45_9606

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RAD51-AS1: RAD51-AS1 is a long non-coding RNA (lncRNA) that has been investigated for its potential role in mediating the anticancer effects of melatonin [PMC6162454]. In a study comparing pSS or "Sicca" versus normal, a total of 57 commonly up-regulated or downregulated genes were identified, and among them, RAD51-AS1 was one of the five lncRNAs that accounted for approximately 8% of the differentially expressed genes (DEGs) [PMC8079748]. The study conducted a rescue assay to verify whether melatonin's anticancer effects were indeed mediated by RAD51-AS1 [PMC6162454]. The results were supported by Figures 2A, B, Supplemental Figure 1, Supplemental Table 5, and Supplemental Table 6 in the study [PMC6162454]. These findings suggest that RAD51-AS1 may play a role in mediating the anticancer effects of melatonin and could be a potential target for further research in cancer treatment.

Genome locations

Gene Ontology annotations

Sequence

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CUUCUCCCCGCUUCCGCCCUGCGCGCUAACCCAAGACGGGAGCUCGAGAGCUUGAUCCUGCGCGAGUUUACAGACUGCCCUCUUCCCUUUUUGCAUCGAAGACCACGACUCCCAAGAGGUAAUGCGUCGGCCCGGGACUACAUCUCCCGGCAUGCAUCGCCGGCGGGUCCGCGAGUUCUCACCAUCGCAGCUGGACUAUUAGCGGGGGCCCUAGCGCUCUUGUGGUUUGUUUCGGCAGUAUCUGAAUGUCAGCUUUUGGCACUUCUGGUCGCUCUGAGCCUCCUACUCGCAUUCCUGGAGCAAGGUGCUUUCCAGGCCUCAUGGAGGUGGAGGAGCUGAGGAAGCUCGAGAAGAUGGAUAGAAGUGGGAAAUGGAGCUAGCGUACGGGAGAGGGAAAUGGCUGGAAUAUUCGUCAAUCUGUGGUGCUUUACUGGAGAUUUGCAGGAGUUCAGAGGAAGGGGGCAUUGAAUUUCAUAACCUAAACCGUAUCGUGGUUUACCAGAAAGUUUUGACCCGUGAUUCCGGUUUUAAAGGCUGAGUAGGGCCGGGCGCGGUGGUUCACGCCAGUAAUCCCAGCAGUUUAGGAGGCCAAGGCAGGCGGAUCACCUGAGGUCAGGGGUUGGAGAUAAACCUGGCCAACGUGGUGAAACCUCGUCUUUAGUAAAAAAUACAAAAAUUAGCCAGGUUUUGUGGCACAUGCCUGUAAUCCUAGCUACUCGAAAGGCUGAGGCAUGAGAAUCGCUUGAACUCAGGAGGAGGUUGCAGCCAACCGAGAUCUCGCCGCUGUACUCCAGCCUGGGCGACAGAGCGAGACUGUGUCAAAACAACACCACAAGCUAGCUGAGUAGGGAUUCUUGGGCGAAGUGGAAGACAUUAUAAGCAAAUAGGGUAGUAUGGGCAUGGAAACGAACUACAUGAUUAAAGAUUAGUAUUAUCUGGCGAGGGAGGAAAAGUGCCAGAGCAAGUGCCGAAACUGGAAGGUUACAUUUAGUUCAGGAUAUGAAGAUCAUAUAAGGCCUGCACGGUGGCUCACACCUGUAAUCCCAGCACUUUGGGAAGCCAAGGUGGGGGAGGAUCGCUUGAGCUCAGGAGUUGGAGACCAGCCUGGGCAACAUAGUGGGACCCCAUAUCUCAAAAAAAAAAAAAAAAAAAAUAA

Taxonomic tree

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Publications