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Homo sapiens (human) SLFNL1 antisense RNA 1 (SLFNL1-AS1) URS000075B9EA_9606

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SLFNL1-AS1: SLFNL1-AS1 is a long non-coding RNA (lncRNA) that has been studied in various contexts. It has been identified as one of the nine lncRNAs that overlap in two sets of hub genes [PMC7851899]. SLFNL1-AS1 has also been found to be negatively co-expressed with hsa-miR-34a-5p and positively correlated with the transcriptional levels of GINS1 [PMC9462653]. In terms of prognosis, SLFNL1-AS1 has shown statistical significance in colorectal cancer [PMC8221294]. Additionally, SLFNL1-AS1 is one of the genes impacted by the rs28714259 risk allele, which reduces its upregulation by dexamethasone and doxorubicin combination treatment [PMC9684507]. In various ceRNA networks, SLFNL1-AS1 is consistently identified as a hub-lncRNA and a potential marker for diseases such as colorectal cancer and chronic obstructive pulmonary disease (COPD) [PMC8377501] [PMC9547624]. Furthermore, SLFNL1-AS1 has been found to be down-regulated in colorectal cancer cell lines compared to normal cell lines [PMC8442393]. It is also implicated in CRC progression through its association with specific miRNAs such as miR-500a-3p, miR-370-3p, miR2467-3p, and miR5123p [PMC8442393]. References: [PMC7851899] [PMC9462653] [PMC8221294] [PMC9684507] [PMC8377501] [PMC9547624] [PM8442393]

Genome locations

Gene Ontology annotations

Sequence

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AACUGAAGUGUGUUCUGUGGAACACUAGUCCUGUGAAAUGCCCUGUUCAACAAGGUUUGGUGAUUUUCUGGUGGCUCAGACCCCAAAUUUAGGAGUAUCCUUAAUUGUCUCACCAGCAGGUAUUUAUUGGGUGUCUACCAUAUGCCAGCCAUACCCAAACCCCUGUCCCCCAGAGCAGUUAUUCAGUGGGGGAAGCACCAAAUAUAAGCUACAGAGUGUGGUAGUUCAUAGAUGGAGACCAGGGGUGGAAGUGAGCAGGGGAGUGGCAGUGCUGGGAGGUGGUGUCUUUAAAAUAGGGUGGGUGGGAAAUUAAGCAUGGACUUGAAGGUGAAGAGGAAAGGAAAUAGGCCGCUAUGUAGCGCAGAGGCCCCGAGGCAGGAGUGCAAAUGAAACAAGUUGGUGGGCGUGGCUGAAGUGGCUUACAUAAGGGGCGGAAGACAUUGAGGUUGGGUGGGCUAGGUGGUGGAGAACCAUGUAGGCCAUCAAGUUUGGGCUUUGCUCUUGAAGAAUUUGGAGGGCUAUGGGUGCAGGUGUGGCGUGAGUGUGAUCAGACUCUGGCUUUGCAGCCUCUGGCUCAGCUGGUGGAGACAGCAGGAGAAACGGCCAGAGGCAGGAAGCAGCUGGAGGAGUCUGGUUUUUUUUGUUUGUUUUAAGCUAACGGUCUUACUGGACCAGAGGGGUCUUGGAAAGGAACUGAGACCCUUAGUGUGAGGUGCUGCUCUGUGCCACAGCUGGCGUAGACACAGGGCACUGGCCCGAUGGUGACAAAAUGCCCCUGGCCAUUGUCACUGUCUUAUAGAUGAAGAAACUGAAGCACAGAGGCAUAGCACUUUGCCCCACGGUCCCUGGUCUUUAAGACAGAGCUGGACUGGAGUCUGAGGGGCUGGGCUCCCUGCCCUUGCAGGUCUGUCCUCUGCCUCCUGGACAGAGGUGGGCUGGGCCUGGGACUCAUGACCCUGCAGCAUCUGACCGGCUGACCCAGUGUCCUAGAAAGAACCAUUCUUGUCCCAGGUGCAUGUAAUUUAUUAAUGGAGCUUUGACAGUCACAAGUUCCAGCAAGUCAGGGGUGGGGGCUGCAGGGUGGCCUCUUGCCCUGUAACCACAGUCAUCAAAUAUGCCUCGCCAUCUUUGAGGGGCUUUCCUGAGAUGACAGAUUCCUUUCUGGCACUGUGUAGCCAACUGGAGUCACAGACCUCAGCCUGGGCCAAAUGAGCAUUUUAGGGAGAAGGACAAUCCCUUAUAGCUUAGCCCUAGGGGAGCUCUGGGCAGGGUUUUACACAUUCUUUCUGAAAGUAAGGUCAUUUGGGGACAGGGCUGAGAGCAGUUUCUUGGCUACACAGAUGGGUCUGUCAGGGUUGAAGCCACAUGGGUGCCUGCUCAUGUGCCAUGUUGAAGGAGUCCCUGUCCGCCUCUCAGCAGCCCGCAUGGGCUUUACUGGUUGGCCUUACACUCAAACAGGAAAUCCCUGGGUCUCAGGUGGAGAGUGCCGUGCCGUCCUGCCUGCUCCCCAGGGCCCUCACAGGACACAGCAGGUGCAGGACACAGGCCCGUGCUGCUGCAGCUGCUGCUGGAGCUGCUCCUUCUCCAUCAUCAGCGCCUUCAUCUUCUCUUCCAGCUUGCCCAGCUCCACCAGCCACCUCUGAGGGGACAUGGGAAAAGCAUGUGGCCAAGCCCGCCUGGUCUCGGGCCUGUCCGUCCUCCACCUGGGGCCAAACUGAGGGAGGAAGGCAAAGCCCAGGAGCCUGAGAGCUUUCUCAGCUAGGGGAAAAGUCAGGCCCCUCGGCCUGCUGCCACCUUCAACCGUGUCAGCCUGAGGGAAGCUGCCGGCUGCCAGCCAUGGAAGGGAGCCUCCUCCGUGCUGGGCAGGCCAUGUGCCUCCUCACUGUUGGUCCCUUGUCCUCCAUUCUCUGUUUCCCUCUUGAAAAAGCUCUUCCUUGGGACUGUGUCUUGCCCCCUCUGCCGCUUUAGGGCCUCCCCUAAAAUGCAGUGUAUAGUCUUUGGGGUUUUCUGGUGACAUCUCAACAUUCCAGUCUCUCUGCUCCCUCACUCAAGAUCGAGUGUGUUAACUGCCCAAGUAGAGGGUGAGGGGUUUCAGGCACCCCUGAAGGGAGGAUACUGCAUAGGAUUUUUUUUUUUUUGAGAUGGAGUCUCGGUCUGUCGCCCAGGCUGGAGUGCAGUGGCGCGAUCUCGGCUCACUGCAACCUCCGCUUCCCAGAUUCGAUCGAUUCUCCUGCCUCACCCUCUCGAGUAUUUGGAACUACAGGCGCCCGCCACCAUGCCCAGCUAAUUUUUGUAUUUUUAGUAGAGACGAGGGUUCACCAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUUGUGAUCUGUUCGCCUCAUCCUCCCAAAGUGCUGGGAUUACAGGCGUGAGCCACUGCGCCUGGCCACUGCAUAGAUUUUUAAAAGGAGAGAGCUUGGGCCUCUUCCUUCCCACCAGCCACCUACCCGCGGAGUAUGGGAUGUGGUGUGAUUGUAUUCCAACCCCUUGGGUUCAACGGGGUGAUGCAGGACCCAGGGAACCAUGGUGGCUUGCCCUGGGCUGCUCAGUGGGUGGCUGAAGGGGUCUGGGGUCAGCUCCGCUCCACCCCACCCACUGGCCUCAGCUUCCGUACCUGCCUGCACCACUCCUGGAUGGCGCUGGCAGACAGCGGGCCCUGGAUGCUCCCGUCGCGCCGCAGAAACACCUCCCCCUGGUCUGUCUGGUAGAGUUGCGGCUGGCUCUGGGCCUUGGGGGUGUGCACGGUCAGGCGGAUCACCUUGGUAGGGGCAACAGCAGCUCUGGAGGCGCCGCCCCUCACGGUCGGCAGCCCCCAUCCUGCCAGGCUGCUCAGCAUUGCUCACUGAUUCCUUAGGGCAGGCCAGCAGGGCUGGCACAGGGGCCAUCCCCAGCCUCUUCUCCUGUGGCCCCCAGUCCCGUCCCUGCCCCAGCACUGCCUGGCAGGAGUGCAGGCCAUCGUCUUACUGAGUGAUGACAGAUGACAGGCCCAGAGGCCCUCCUGUCCUGCAGGCUCACCUUGAGGGGGACGCUGGUCUCCGAGGUACUGAUCACAGGGAUGAAGGUGAGAGUGUAGGCAUCGGGAAAGAUCUGAGGCUUGAAGCCCUGCAGGAUGGAGUCCACCAGCAGGCGUGCGCGGUCCUCGUCACGGUGGCUGCAGCGGAUGCCCUGCACCAGGCCGCUGUCCUCUACUCCCACGAGCAGGCUGCCGCCCUCGCUGUUGAGGAAGGCGCACACGUAGCGCCGCACGUGGUGCUUGAAGGCCAGGCUGAGGUACUCGCCGCUACCCCGCUUGAACUCCAUAUUGCGGGUCUCGCUGCCCAGGAAGGCACCCUGGAAGAGCUGGUCCUUGCCCACGAUCUGCUGGUGCACAAUGGCACUGUCGGAGCACACGCCGCUGGGCCGGCCCUGGCAGCUCUGCAGCUGCUGGGCCUGGGGCCUAUCAGGCAGCGUGUGUGUAGGCCAGGUGGGCAGCGGGACACCAGAGCCUGGACUGGGGCCAGGGCUCAGGCCACUGUCCUCCUCCUCCUCCUCCUUCUCCUAGGGUGGUAGUCAAGAAUGAAUGUAUGGGUCCAGCCAGGAAAUGGGAGCCCUGACCCUGAGAAGGACUGCAAGAACCCCCAGUCAGGCCCCUGCUGCAGCCUGACUCUUACGGACAUCCUGAUGCCCCUCACCAGGCCGAGGGGCCCAGUUCUGCCCACCCUCCUGCAGCCGAGGCAGGAAACCCUGCUGGAUCGAGGGUUCCAGUCAGCGCUCCUUUCCCUGCCAAGCUGGGCCCUUCCCAGGUGAGGCUCUCCACACAGGUUCCUACUGAGAGGUCAGGCAGCAGCACCUACGUGUUUGCGAAACAGGUCAGCGUGGGGUCCAAGCUGAGGAUCAGCUUCCCGGACAAACUGCAUCACAUCCUCGACUGUCCAUGAGGAGGGGUCCCGGCCACUCAGUCGAGAGGCAUCGCGGCUCUCCAGAAACACUUCAAGGAAGCUGGGGUUGAUGAGCGACGGAGUCUCACUCUGUUGCUCAGGCUGGAGUGCAGUGGCACAAUCUUGGCUCACUGCAACCUCUGCCUCCUGGGUUCAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGAAUUAUAGGUGCACACCACCAUGCCCAGCUAAUUUUUGUAUUUUUGGUACAGAUAGGAUUUCACCAUGUUGGCCCAGCUGGUCUUGAACUCCUGACCUCAAGUGAUCUGCCCACCUUGGCAUCACACAGUGCCGGGAUUACAGGCAUGAGCCACCGCACCUGGCCUAGUAGUAUUUUAUUAAUGUUAAAUUUCAUUAGUUUUUUUUUUUUUUGAGACAGAGUCUCGCUCUGUCGCCCAGGCUGGAGUGCAGUGGCGCAAUCGCUGCUCACUGCAAGCUCCGCCUCCCGAGUUCACGCCAUUCUCCUGCCUCAGCCUCCUGAGUAGCUGGGACUACAGGUGCCUGCCACCACGCCCGGCUAAUUUUUUUUUUUUUUUUUGUAUUUUUAGUAGAGAUGGGGUUUCACCAUGUUAGCCAGGAUAGUCUUGAUCUCCUGAUCUCACGAUCCACCCGCCUCAGGCUCUCAAAGUGCUGGGAUUACAGGUGUGAGCCACCGCGCCUGGCCUCAUUAGUUUUUAUUUAUGUUAAAUUUCUUAAUCAUAAUAAUACUAUUAUGUUCCUUAUUCUUAGGAGAUAAACACAAAAGUAUUUAAGGAUAAAAUCUCUCAUCUGCAGUUAACUCUCAAAUGGUUCAGUAAAUAAAUGAAAAACAUUUUAAAUAUA

Taxonomic tree

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Publications