v24

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Homo sapiens (human) IL21R antisense RNA 1 (IL21R-AS1) URS000075B66C_9606

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IL21R-AS1: IL21R-AS1 is an interleukin 21 receptor antisense long non-coding RNA (lncRNA) that has been implicated in various diseases, including gestational diabetes mellitus (GDM), coronary artery disease (CAD), and acute myocardial infarction (AMI) [PMC7791915] [PMC8702784] [PMC9845402]. In a study on GDM, IL21R-AS1 was found to have significantly lower expression levels in patients compared to controls [PMC7791915]. In CAD patients, IL21R-AS1 was confirmed to be upregulated in both plasma and peripheral blood mononuclear cells [PMC6037039]. Furthermore, IL21R-AS1 was found to be downregulated in AMI and myocardial fibrosis after AMI [PMC8702784]. IL21R-AS1 has also been identified as a potential biomarker for coronary artery disease [PMC8702784]. In addition, IL21R-AS1 was found to be significantly dysregulated in AMI and MF after AMI, suggesting its potential role in these conditions [PMC8702784]. Furthermore, IL21R-AS1 was identified as one of the lncRNAs associated with mRNA expression levels of various genes including BAALC, HIF1A, TNFRSF14, IRF1, IL1R1, RORA, and CA3 [PMC9845402]. However, no significant difference in expression levels of IL21R-AS1 was observed between multiple sclerosis samples and the control group [PMC6128809]. References: [PMC7940190] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940190/ [PMC7791915] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791915/ [PMC6037039] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037039/ [PMC8702784] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702784/ [PMC9845402] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845402/ [PMC6128809] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128809/

Genome locations

Gene Ontology annotations

Sequence

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AUCACUUCUGCUCACAACUGCCCAGUCCCAGCCAGUCACAUGGCCCCAUCUGGCUACAGAGGGUCAGGAUGUACAAUCCUGCCAUGUGCCCAGCAUAUGGUGAACAGCAUAAUGACUUCCAUACUCAUGUAUCUAAACGGUCCAGGAGAAACGUGGUUUCAGGCAUGGCUGGAUCCGGGAUCUCAAGAGCUAUUACCAUCUCUCAGCUCUGCUUUCUUGUGUGUUUCUUGCUGCCCCUCCCAGUACCCUCCUUACAGCUUAGUAAUCCCAGCAGAAAGAGAGCAUGGACCAGCUAGGGUACGUUCCAGCAGAGCAAGGUGAAAAAGAGCUGAAAGUGGCAUCAGAAGCCCAGAGUUCUGGUUCCAGCUCCGACCACUCAUUCAGUGUGUGACCUCAGGCAGGUCACCAGCCUGAGCUGUGCCUUCAUUUCAUCUGUCAGACGGAUGACUCUGCCCCUCAGAGCUUGCAGACGGCAAGGUGAUAAGGAACAAUAUGGACUUCUUGCAGCUCCUGGAGGCAGACGCUGGAGGGCUGGGCUCCGCCUCAGUCACAGGCAAUGCCCUGAUCCCACAAAGCCCCGGAGAUGCUGUGGACCAACUUGCAACACAAGACCCUAGGAGGGAGGACGGCUGUUGUCAUCUGUUGACCACAAACACGUUUACUGUGCACACUUGUGCACAUGGGUGAGCUCCGUGAGUCCAGACAUGCACAGGGCAGGUGAAUGCAUGGAGUACCAUGGGCAUUAUCCCAGGCCCACAGGCACGUGCAAUCACACACACACGUGGACAUGCCACUGCGCACCUAAGACACACACACACACACACAUGCAUAUGCACACACACACAUAUGCACACACACACACAGACACUGUAAACAUCAGGCUCAAAGGCCCAUCCAGGAGACCAAAGGCUGCAGGUGUCUUCACAUCACAGCCCAGGUGACCUUGUCUCUGGCUCAGGGCCCAGUGGCCUGGCCAGCUCUGGACAUCCAGUCAGCCUCAUUAGCUGGCCUGGGGUCCAGGGCUCGAAAGUGGCGGAGGAAUGACCACCCACUGGCGGAGGUAGCUCCGGGGGGGUCCUUCGUCCCCGGGGCUGGUGAAGUCACACUCCACAGGGCUGCUGCAGUCAGAGCCCACAAAGCCACUGUCAAACGUGUCCAUAUCCAGGCCGGCCAGGGGUGAGCCCGCCUCACUCUCUGAGACCCCUCCAGGUGACCGGCCACCCCAGGGCAGUCCCCCAGCCCAGUCCUCCCCAUCUGCAAGGGGUGGCUUUAGUCUGUCCAGGAGGCUUCCCAGGGGCCCUCCUAGCCCAGGGCUGCCAGCUGAGACACAGCCACAGGACAGGACUGUGGUCCCUGCAUCCAAGAGUGGGUCCUCUAGGCCUGGGCUGGGCUCCAGGCCAGCAUCCAGGUCCAGGGCUGGGUAGCCGUCAUCCUCACAGCUGCAGGGCCAGGUGCAUGGCCCCUCUGCAUCUAGCACAGUCACUGUGUCAAUGGACACCAGGCCGUAUGGCCGAUCCCUCUCCUCACUGUAAGCUGAGCCCCCCGAGUUCUGGGCUGUCGGCCAGAAGCUGGGCUUGGGCACACCGUCAGACUCCACCAGCUCUGCUGGUUCUUGUAGCUCCGUGAGCUGCAGCCUCUUGGCCGGGCUCCGUGGUGGGUGGCAGCUGUACACCUCCAGGGUGGAGGGCACCUCUGGGCUCCAGGGUCCCAGCUCCAGGCUGGAGCCAGUGAAGGGUGCACCCACCCAUUUCUGUGAGAGAGAAAAAGAGAGAGUCAUAGCACAGGAUGAGGGUAAGGUGAGGGUUUAUUUUUCUUUUACUUUUAUUCUUUUGAGACAGUCUGGCUCUGCUGCCCAGGCUGGAAUGCAGUGGUGCCAUCUCGGUUCACUGCAACCUCUGCCUCCCAGGAUCAAGUGAUUCUCCUGCCUCAGCCUCCCAAGUAGCUGGGACUACAGGCGCCUGUCACCACACCCGGCUAAUUUUUGUAUUUUUAGUAGAGACGUGGUUUCACCAUGUUGGCCAGACUGAUCUUGAACUCCUGACGUCAGGUGAUCCACCCGCCUCAGCCUCCCAAAGUGUUGGGAUUACAGGCGUGAGUCACUGUGCCCAGCCAAGGUGAGGGUUUAAACAGACAGAAAGACAGACACAGACACAGAGACAAGACAAAGAGACAUCAAGAGAGACAGACAGAGACAUGAAGAUAGACAAAGACACCGAGAGACAGAGAGAGAGAGAGGAAUCAGGACCACAAUGUGCUCCCACCCUAGUGGAUCCCCCUCCUACUCUGGGCCUCAGUUUCCCUACUUGUAGAAGGGAGUUGCUACCCUUAGUAGUGUGACCAGUCAGACAACUGGUGGCCCCAUAGUCCAGGCAGGGACCAAGAUUCCUGAGUCAAGGAGACAUGGGGGCAGGAGGGCCUGAGGUCUGAGGUACCCCUGAGCCAUCUCCUGCUUUCCCGCCUCCUUGAUGCUUCUUGAAACCUAGCACUCUCCUGGUUUAUGUGUCCCCACCAGACAGACACUUGGCCCCCGGACAUAAGUCUUGUCUCUUCUGUCCAUGGCUGUAGCCCCAGUGCCUAGCACAAAGUAGGUGCUCAAUAAAUGUUUAUUAACGAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications