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hsa-mir-4311: Hsa-mir-4311 is a microRNA that has been studied in relation to various biological processes and diseases. It has been found to interact with several other microRNAs, including hsa-miR-3163, hsa-miR-3065-5p, hsa-miR-551b-5p, and hsa-miR-875-3p [PMC6005163]. In silico analysis has identified nine miRNAs, including hsa-mir-4311, that may have common target genes [PMC7407898]. Hsa-mir-4311 has been linked with downstream genes such as ZYX, PRKAR1A, BTAF1, LRP3, and ETS1 [PMC7050132]. It is also associated with single nucleotide polymorphisms (SNPs) that may affect its function and regulation of mRNA production and stability [PMC4134282]. Hsa-mir-4311 has been found to interact with LINC00472 in a ceRNA manner [PMC8974029]. The binding between hsa-mir-4311 and LINC00472 has been confirmed through dual-luciferase assays [PMC8974029]. Hsa-mir-4311 may also regulate the expression of GNG7 as its downstream protein effector [PMC8974029]. The expression of hsa-mir-4311 is significantly increased in human oral squamous cell carcinoma (OSCC) cells compared to normal human oral keratinocytes [PMC8974029].
References:
[PMC6005163]
[PMC8902122]
[PMC7407898]
[PMC7050132]
[PMC4134282]
[PMC4671954]
[PMCID: PMC8974029]
Genome locations
Gene Ontology annotations
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