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Homo sapiens (human) LYPLAL1 divergent transcript (LYPLAL1-DT) URS000075B5F8_9606

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LYPLAL1-DT: LYPLAL1-DT is a long non-coding RNA (lncRNA) that has been found to inhibit miR-204-5p, leading to an upregulation of SIRT1 expression [PMC9068612]. This suggests that LYPLAL1-DT plays a role in regulating the expression of SIRT1, a gene involved in various cellular processes [PMC9068612]. LYPLAL1-DT is expressed in diverse human tissues, including vascular tissue and endothelial cells (ECs) [PMC9068612]. This indicates that LYPLAL1-DT may have functional significance in these tissues and cells [PMC9068612]. The specific mechanisms by which LYPLAL1-DT inhibits miR-204-5p and upregulates SIRT1 expression are not mentioned in the given context. However, further research may provide insights into the molecular interactions involved. Understanding the role of LYPLAL1-DT and its interactions with miR-204-5p and SIRT1 could have implications for various biological processes and potentially contribute to the development of therapeutic strategies for related conditions or diseases.

Genome locations

Gene Ontology annotations

Sequence

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AUGCGCAGCGCUGCUGGCCCGCUCUCUGAGGAGCUUUCAAUACUUUGGGGUCAAGUUUGAGGCAGUUGUAACUGUACUGAGUUUAGUUUUGCUAAUAAUGGUAUUCUACGUGUGUCAGCCUCGUGUGGACUUCUGUAAUGACUAAUGGAUAUGUUUAUAUCCUGAGCAUUUGCUGUAGGAAUUUUAAAUGCAAUCCCAAAACUCAAGAUUACCUUAUUUGGAGAAAUAUUCGUGUUACUAUGUUUAAAAUUUAAUAGAACCAUAUUUUACCUUUCACUUUGGGACUCGCACAGGAUGUUUGCAGCUCUUGAUAUACAGGAACUAGAACGUGUCUUUUAAGAGCAUGCGGUUUUAUAAUUACGUGGAAGUAUGCUACGCAAGGGAAAAAAGCCUCUUGCUAGUGUUAAGGGUCUUCAUAAACAGAAACCGCAAGGAACCUGGGAUCUGACAGCUGUUGGAGGAAUGCCUGUGAGGAAGGAGGAGGAACAGAAGAAUGCUUUGAUGUCUUAAAUGGUACAUCCAAACUUAAGUGAAAUAGAGCUGUGAGGACAUUUUGGGGAGAAGUGACCUAGAUAAGCACUGACUGUUGCAUUCAUCUCUCUUCUUGCUGAUUGUGAUGAUUUCCUGUGCCAUAGCCAUUCAAAGUCUGCCAAAAAAGGCCUUGCCUCCUGGAUGGCAUUUUUGAACCCACCCUGGGCCAGAGGGGAGCCCACUUCUUUGAAGACAGAAACACAGGACUGGCAACAUUUACCAUAAGCUGACUGAGCAGCCAUUGGGCCUUGAGUGAACAUUGGUGGUAGCCAGGCAGUACUUGUCUCAGUACUUGCCUCAGGCCUGGGGUGUCGGUGACCACAGGGAGAGCAUCCAUCUGCUUGAGGAAAGGAGAACAAAGAAAAUAAAGGGCUUAAUCUUGCACUUGAUUGCCAGCUCAGCCAUAGUAGAAUACAGCACCAAGUAAAUUCCUAAGGAUCCUGAUUCCAGGUCCUGGCUCCCAGAUGACAUUUUAGGACUUGUCUUGGGCUUAGGGGGAGCUCGUCAUACUGAAGGGAAAAACACAAGCCUGGCUGGAUUUGCCACCAGCUGAAUAAAGAGUGCUUGGGCCUUGAGUGAACAUUGGCAAUAGCCAAGGAGUGGUCACCAUGGACCUUAGGCAAGAAACCCGGUGCCGUGCUGGCUUUGGAUCUGACCCAGCAUAAUCUCACUGGUAUUUUACUUCUUGUCCAUUUACUUUUUAGUUUAUCAUACACACCAUGUUUACUAGUACUAAAACUGUCUUAAAAUAUUGCAAUUUUGACCCUUUUUCUAAUUGACCUUUAUGUUUUUACAAGCACAUUUUAUUACAUAUGAAUGAGACUUUACUAUGUUAUAUGUAACUCUUAAUUCUGUAAAUAAUAGAUUGCUUAUCUGAAAUAUAGCUGAUAUUUGUUUCUUAAUUAUUUGGCUAUUCCCUAUAUGUUAUACUCUACUAAAGAUCAUGGGAUUUAGAUUCAGAAAACUUACUUCCUAGCUCUUAUUAUUUCUGUGAUCUUGCAAAAGAAAACAAAAAUGAACCAUUGUUUUUUUAUCUGUAACAGGAAAUGUACUUCACAGGAUUGUAAUGAGAAUUAAAUUAGAUAAUAUACAUGAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications