hsa-mir-3934: Hsa-mir-3934 is a microRNA that has been found to be correlated with survival rate and disease development in patients with non-small cell lung cancer (NSCLC) [PMC6676217]. It is one of the miRNAs that were not previously detected to be differentially expressed during control myogenesis [PMC4186784]. While 26 miRNAs were already reported to be involved in muscle differentiation, hsa-mir-3934 was not previously known to be involved in this process [PMC4186784]. In a study on cardiac marker genes during hypertrophy and other cardiac diseases, hsa-mir-3934 was identified as one of the miRNAs that may play an essential role in regulating these genes [PMC3842578]. The secondary structure analysis showed that hsa-mir-3934 has a strong binding affinity with the 3′UTR of the BTD gene [PMC8846296]. In breast cancer, hsa-mir-3934 was one of the seven miRNAs included in an optimized prognostic gene signature and a MiR Score prognostic model, which showed a high forecast ability for breast cancer prognosis [PMC7236498]. Furthermore, hsa-mir-1911, hsa-mir-3934, and hsa-mir-526b were found to potentially target UNC5C, a member of the UNC-5 family of netrin receptors [PMC7236498]. However, further studies are needed to confirm this association in breast cancer patients [PMC7236498]. Additionally, hsa-mir-3934 was identified as one of the differentially expressed miRNAs in smoking-associated lung cancer using TCGA LUAD dataset analysis [PMC6257755]. References: [PMC6676217] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676217/ [PMC4186784] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186784/ [PMC3842578] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842578/ [PMC8846296] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846296/ [PMC7236498] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236498/ [PMC6257755] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257755/