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MIR654: MIR654 is a microRNA that has been found to be associated with various biological processes, including carcinogenesis [PMC9224266]. In ovarian cancer cells, the long non-coding RNA EMX2OS can directly bind to MIR654 and inhibit its expression, resulting in the upregulation of PD-L1 and the promotion of proliferation, invasion, and spheroid formation [PMC8974003]. However, MIR654 was not detected in head and neck cancers [PMC5354851]. Several studies have shown that MIR654 can inhibit the replication or propagation of influenza virus [PMC3774802]. Additionally, MIR654 has been found to bind to PB1 in MDCK cells and inhibit the replication of H1N1 virus [PMC5360757].
In a study on prognosis, 10 miRNAs were found to be associated with a good prognosis [PMC9924325]. Furthermore, four long non-coding RNAs (lncRNAs) and three miRNAs were found to regulate AZGP1 [PMC9924325].
Overall, MIR654 is a microRNA that plays a role in various biological processes including carcinogenesis. It can be regulated by long non-coding RNAs and has been shown to have inhibitory effects on influenza virus replication. However, its expression may vary depending on the type of cancer or infection.
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