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hsa-mir-1295b: Hsa-mir-1295b is a microRNA that has been implicated in the protumor process of MACC1 and may serve as a diagnostic biomarker and therapeutic target for cholangiocarcinoma (CCA) [PMC6451803]. In a study, three prognosis-related miRNAs, including hsa-mir-1295b, hsa-mir-33b, and hsa-mir-6715a, were used to construct a competing endogenous RNA (ceRNA) network [PMC6451803]. The study also revealed correlations between these miRNAs and seven long non-coding RNAs (lncRNAs), including COL18A1-AS1 [PMC6451803]. Low expression levels of hsa-mir-33b, hsa-mir-1295b, and hsa-mir-6715a were associated with poor overall survival in CCA patients, suggesting their potential as therapeutic targets [PMC6451803]. Furthermore, the study identified several miRNAs (including hsa-mir-1295b) as prognostic markers for CCA [PMC6451803]. Hsa-mir-1295b was found to be significantly downregulated in colorectal cancer and has not been extensively studied in other cancer types [PMC6451803].
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