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MIR3185: MIR3185 is a specific primate genome miRNA that has been studied in relation to fatigue and mood disturbance [PMC9105576]. In a study involving 30 participants, an inverse correlation was observed between MIR3185 and the gene PGK1, which is a potential biomarker for fatigue [PMC9105576]. Additionally, MIR3185 was found to be correlated with the TMD and FI subscales, which assess mood disturbance [PMC9105576]. The levels of MIR3185 and PGK1 were found to be responsive to changes in mood state and fatigue [PMC9105576]. The study suggests that MIR3185 may regulate the expression of PGK1 in response to changes in fatigue levels [PMC9105576]. Furthermore, luciferase reporter assays were conducted to investigate the effects of MIR3185 on ATG5, ATG7, and Linc02527 genes in HTR8 cells [PMC6155230]. These findings contribute to our understanding of detectable changes in exosomal biomolecular composition and highlight the potential of PGK1 and MIR3185 as biomarkers for mood- and fatigue-associated cognitive impairment [PMC9105576].
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Gene Ontology annotations
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