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Homo sapiens (human) microRNA hsa-mir-142 precursor URS000075AE07_9606

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MIR142: MIR142 is a small molecule that plays a role in various biological processes. In Sgca-/- mice, the expression of MIR142.3p-regulated vector decreased over time [PMC4283385]. MIR142−/− mice, which lack the MIR142 region, were obtained from the mouse facility of the German Center for Lung Research [PMC6910913]. The interaction between MIR142 and IDHR140 mutations in leukemogenesis was investigated [PMC7656267]. The occurrence of mutations in MIR142 was analyzed in a collection of samples from patients with myeloproliferative neoplasms (MPNs) [PMC9240003]. MIR142 was found to regulate autophagy by targeting ATG16L1, suggesting its involvement in intestinal inflammation and Crohn's disease [PMC6351131]. Chronic alcohol consumption was found to alter the expression of MIR142, among other small RNAs and microRNAs, which may be mediated by effects on epididymal trafficking rather than changes in corticosterone levels [PMC9886817]. Additionally, MIR24 and MIR142 were identified as miRNAs that target over 1,000 genes each [PMC7287171]. AAV2 plasmids containing the gene encoding GFP under the control of a hybrid sequence including 4 repeated sequences of MIR142 were used for vector purification [PMC7184633]. Overall, these studies highlight the diverse roles and regulatory functions of MIR142 in various biological processes.

Genome locations

Gene Ontology annotations

Sequence

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GACAGUGCAGUCACCCAUAAAGUAGAAAGCACUACUAACAGCACUGGAGGGUGUAGUGUUUCCUACUUUAUGGAUGAGUGUACUGUG

Taxonomic tree

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This sequence is found in 72 other species

  1. Ailuropoda melanoleuca microRNA 142 (ENSAMEG00000022130.2)
  2. Aotus nancymaae (Ma's night monkey) microRNA 142 (ENSANAG00000011297.1)
  3. Artibeus jamaicensis microRNA aja-mir-142 precursor
  4. Balaenoptera musculus microRNA 142 (ENSBMSG00010014869.1)
  5. Bos grunniens microRNA 142 (ENSBGRG00000012558.1)
  6. Bos indicus x Bos taurus miRNA (ENSBIXG00000009569.1)
  7. Bos taurus microRNA bta-mir-142 precursor
  8. Camelus dromedarius (Arabian camel) microRNA 142 (ENSCDRG00005022166.1)
  9. Canis lupus dingo microRNA 142 (ENSCAFG00020025799.1)
  10. Canis lupus familiaris miRNA (ENSCAFG00000020626.2, ENSCAFG00030008298.1, ENSCAFG00040000054.1, ENSCAFG00845020364.1)
  11. Capra hircus microRNA 142 (ENSCHIG00000001668.1)
  12. Carlito syrichta (Philippine tarsier) microRNA 142 (ENSTSYG00000020736.2)
  13. Castor canadensis (American beaver) miRNA (ENSCCNG00000023137.1)
  14. Catagonus wagneri (Chacoan peccary) microRNA 142 (ENSCWAG00000018463.1)
  15. Cebus imitator (Panamanian white-faced capuchin) microRNA 142 (ENSCCAG00000032446.1)
  16. Cercocebus atys microRNA 142 (ENSCATG00000020574.1)
  17. Cervus hanglu yarkandensis microRNA 142 (ENSCHYG00000017115.1)
  18. Chlorocebus sabaeus (African green monkey) microRNA 142 (ENSCSAG00000021330.1)
  19. Colobus angolensis palliatus miRNA (ENSCANG00000020450.1)
  20. Dasypus novemcinctus (nine-banded armadillo) microRNA 142 (ENSDNOG00000026448.1)
  21. Echinops telfairi (small Madagascar hedgehog) microRNA 142 (ENSETEG00000021490.1)
  22. Equus asinus asinus microRNA 142 (ENSEASG00005002791.1)
  23. Equus asinus (ass) microRNA 142 (ENSEASG00005002791.2)
  24. Equus caballus (horse) microRNA 142 (ENSECAG00000026328.2)
  25. Erinaceus europaeus (western European hedgehog) microRNA 142 (ENSEEUG00000016026.1)
  26. Gorilla gorilla gorilla microRNA 142 (ENSGGOG00000032439.2)
  27. Heterocephalus glaber (naked mole-rat) microRNA 142 (ENSHGLG00000022522.2, ENSHGLG00100023981.2)
  28. Loxodonta africana (African savanna elephant) microRNA 142 (ENSLAFG00000027413.1)
  29. Lynx canadensis (Canada lynx) microRNA 142 (ENSLCNG00005018269.1)
  30. Macaca mulatta microRNA mml-mir-142 precursor
  31. Macaca nemestrina (Pig-tailed macaque) microRNA 142 (ENSMNEG00000006248.1)
  32. Mandrillus leucophaeus (Drill) microRNA 142 (ENSMLEG00000013133.1)
  33. Marmota marmota marmota microRNA 142 (ENSMMMG00000020498.1)
  34. Meriones unguiculatus miRNA (ENSMUGG00000025514.1)
  35. Microcebus murinus (gray mouse lemur) microRNA 142 (ENSMICG00000018193.3)
  36. Moschus moschiferus (Siberian musk deer) microRNA 142 (ENSMMSG00000014741.1)
  37. Mustela putorius furo (Domestic ferret) microRNA 142 (ENSMPUG00000020206.1)
  38. Myotis lucifugus microRNA 142 (ENSMLUG00000030399.1)
  39. Neogale vison microRNA 142 (ENSNVIG00000012975.1)
  40. Nomascus leucogenys (Northern white-cheeked gibbon) microRNA 142 (ENSNLEG00000021129.2)
  41. Ochotona princeps microRNA 142 (ENSOPRG00000017740.1, ENSOPRG00000018512.1)
  42. Oryctolagus cuniculus (rabbit) microRNA 142 (ENSOCUG00000018728.2)
  43. Otolemur garnettii (small-eared galago) microRNA 142 (ENSOGAG00000017459.1)
  44. Ovis aries (sheep) microRNA 142 (ENSOARG00020019675.2)
  45. Pan paniscus (bonobo) microRNA 142 (ENSPPAG00000011531.1)
  46. Panthera leo (lion) microRNA 142 (ENSPLOG00000012736.1)
  47. Panthera pardus microRNA 142 (ENSPPRG00000013572.1)
  48. Panthera tigris altaica miRNA (ENSPTIG00000003325.1)
  49. Pan troglodytes ptr-mir-142 (ENSPTRG00000027845.2)
  50. Physeter catodon (sperm whale) microRNA 142 (ENSPCTG00005009782.1)
  51. Pongo abelii miRNA
  52. Pongo pygmaeus (Bornean orangutan) microRNA ppy-mir-142 precursor
  53. Procavia capensis (cape rock hyrax) microRNA 142 (ENSPCAG00000019870.1)
  54. Prolemur simus microRNA 142 (ENSPSMG00000004093.1)
  55. Propithecus coquereli (Coquerel's sifaka) microRNA 142 (ENSPCOG00000001762.1)
  56. Pteropus vampyrus (large flying fox) microRNA 142 (ENSPVAG00000025678.1)
  57. Rattus norvegicus (Norway rat) microRNA rno-mir-142 precursor
  58. Rhinolophus ferrumequinum (greater horseshoe bat) microRNA 142 (ENSRFEG00010014735.1)
  59. Rhinopithecus bieti microRNA 142 (ENSRBIG00000005489.1)
  60. Rhinopithecus roxellana microRNA 142 (ENSRROG00000012402.1)
  61. Saimiri boliviensis boliviensis (Bolivian squirrel monkey) microRNA 142 (ENSSBOG00000012670.1)
  62. Sciurus vulgaris (Eurasian red squirrel) microRNA 142 (ENSSVLG00005011297.1)
  63. Sorex araneus microRNA 142 (ENSSARG00000016670.1)
  64. Spermophilus dauricus miRNA (ENSSDAG00000020528.1, ENSSDAG00000020529.1)
  65. Suricata suricatta microRNA 142 (ENSSSUG00005019666.1)
  66. Urocitellus parryii microRNA 142 (ENSUPAG00010014022.1)
  67. Ursus thibetanus thibetanus (Asiatic black bear) microRNA 142 (ENSUTTG00000019019.1)
  68. Vulpes vulpes microRNA 142 (ENSVVUG00000012499.1)
Publications