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Homo sapiens (human) DLGAP1 antisense RNA 1 (DLGAP1-AS1) URS000075ADDB_9606

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DLGAP1-AS1: DLGAP1-AS1 is a novel biomarker for glioma patients' prognosis [PMC8941517]. In a study, it was found that DLGAP1-AS1 and TGFB2/Smad2 signaling pathway activities were decreased, while miR-149-5p expression was enhanced in tumor tissues originating from HT-29 cells transfected with sh-DLGAP1-AS1 [PMC7985718]. This suggests that DLGAP1-AS1 may play a role in glioma progression and may be involved in the regulation of the TGFB2/Smad2 signaling pathway [PMC7985718]. The decreased activity of the TGFB2/Smad2 signaling pathway and enhanced expression of miR-149-5p in tumor tissues transfected with sh-DLGAP1-AS1 may contribute to the progression of glioma [PMC7985718]. These findings highlight the potential importance of DLGAP1-AS1 as a biomarker for glioma prognosis and suggest its involvement in tumor development through modulation of the TGFB2/Smad2 signaling pathway [PMC7985718].

Genome locations

Gene Ontology annotations

Sequence

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AGCAGCUGCCCCUGCAAAUGUCAGCGCCAGCCCAGUCAAAAGAGCUUGAAACCUACCAAGCCGGAGGACUGUGCUGUGCCUCUCUCGCCCACAUUUUCCCCAAGCACUCUCAGGAACCUGGCAACAGUGUCCCCUUGUGGCCAAGCCUGGAACAUCACAUCUGUACGUUGCAAUCUGUGGAUCAGCUACGAGACUGAGAGAAAGGAAUGAAAGGAUGGAAGAAUUACAAGAUCAGGCACUGCUGUCUGUCUGUUCCACGGAUGUAACCACAGCACACGCGUGGCUCACGGUACUAGUGUGAUAAAUGCUUGUUACAUGAAGGCGUGAACAGGGAUGAGAAGAGACUUCCUGGAGAAACAAAAGGACUAACAAUCAGGAAGGGGAGGUGAUCGGGGCAGGAGUAAAGUGGACACCUCAGCAAAGCCAUUCGCUGUGAUCUCUGAUUGUGCAGUGUCAUGUCCUGUCACCAGAGCCCCCUCGUGUUUGAUGUUGGCCAAUGCCGCCAGCAUGAUCUAGCAGGCCAAAUCCUAAUCUACCAUUCUCUGACACCAGCUGGUCCCCUGGGUCGUCCACCCGAUGUCCCCCAUUCUCCCCACUUGGCCUCCCCCACAGGCUCUCGGCAAAGGACCGUGGGAGGCACCUGUGACACUGCCCUUUUCCUGUGCAGCUGUUUUUCUUCUUCAUUCUUUUCACUCCUCGUUACUCUUUUUUUUUUCACUCUCAGCCCACACAAAACUAGGAACUUUGUUAUUCUACUUAUUUUUCUGUACUCUGUCUGUUUGCACACAGAUGGAUAUCUGAGAGCCAGCGAACUUUCUUUACCUCCUAGUAUCAUUUCAUGAAAAUUAGUAGCACCUGCACAAUGGGGCCUUGGAGACAGGAAUAAAAGGAAAAAUCUGGAAUGGAAUCACAUGACGCAACAGGCUAUGAAGACUCCCUGCCCGGCUGCUAUAUGUCUGGUAAACAGAAUAAAUAGUACUUGAGCAUCCCUGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications