MIR605: MIR605 is a microRNA that has been found to regulate the p53-MDM2 interaction and is a transcriptional target of p53, participating in a positive feedback loop by degrading MDM2 [PMC3248149]. However, the allelic and genotypic frequencies of the SNVs selected in TP53, MDM2, MIR605, and LIF were not statistically different between CZS and control groups [PMC8294037]. In a study evaluating the effect of ZIKV infection on gene expression in human neuroprogenitor cells (hNPCs), it was found that ZIKV infection did not alter the expression of MIR605 [PMC8294037]. One polymorphism in the MIR605 gene (rs2043556) was significantly associated with infectious-type toxicity during ALL treatment [PMC10003057]. This variant has also been linked to the development of various cancers and may affect the functionality of the MIR605 processing gene [PMC10003057]. Additionally, it was found that variants in genes such as MIR149, MIR938, MIR200C, and MIR2053 were associated with neurological toxicity during ALL treatment [PMC10003057]. These findings suggest that variants in genes like MIR149 and MIR605 can influence toxicity during cancer treatment by playing regulatory roles in cellular environments [PMC10003057]. Overall, these studies highlight the importance of microRNAs like MIR605 in regulating gene expression and their potential role as biomarkers for treatment response or toxicity prediction.