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Homo sapiens (human) cancer susceptibility 16 (CASC16) URS000075AB2F_9606

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CASC16: CASC16 is a gene that has been studied in relation to its polymorphisms and their association with certain diseases. In a study, linkage disequilibrium (LD) and haplotype analyses of CASC16 polymorphisms were conducted in cases and controls [PMC6988193]. Additionally, two intronic variants of FGFR2 were reported [PMC5809862]. CASC16 is a long non-coding RNA (lncRNA) gene that has been implicated in various diseases, including cancer. It is located on chromosome 8q24.21 and has been found to be dysregulated in several cancer types, including breast cancer [PMC6988193]. The study on linkage disequilibrium and haplotype analyses aimed to investigate the association between CASC16 polymorphisms and breast cancer risk. The results of the study provided insights into the potential role of CASC16 variants in breast cancer susceptibility [PMC6988193]. In addition to studying CASC16, the researchers also reported two intronic variants of FGFR2. FGFR2 is a gene that encodes a receptor tyrosine kinase involved in various cellular processes, including cell growth and differentiation [PMC5809862]. The identification of these intronic variants adds to our understanding of the genetic variations within FGFR2 that may contribute to disease susceptibility or progression [PMC5809862]. Overall, these studies contribute to our knowledge about the genetic factors involved in disease development and provide potential targets for further research or therapeutic interventions.

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Gene Ontology annotations

Sequence

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AGAAUGUUCCUUGCUGCAGAUGCAUUGGCCCCAUCUGCAGGUCCUCUUUGACACCUACCUUACUCUCUCCCUCCACUCACACUCUGAGAACUGUGCUCAGGGGCAGCGCUACAACUUCCACAUUGGUCUUUACAGGGCUUGAGUGAUUAUUUCAAGAACAGAACGCUGUGUGGAAACCUUUACCAUAUUUCGUUGUAUCUAAGACACAUUUUUUUUUUUUGAAAUUUAACAUCUCUAAGGUUGGGUUAUGUUUCUUCAUCAUUGUCAGGUUGGAGCUUAAUCAGCAGCACUUUUUUUUAAUGUCACACACAGUAAUGGUGAUGCAUCUCACAAUUGAGAUCAUCUUAGACAUGAUGGAAUAUGGAAUCGUGUGCCUGUUACAAGCCAGGCUCUUGUCUGGGUUCUAGAGACGGUGGAAACCAAGACAGCACCAUCCUCUAGUGGUGUUCACAUCCCACCACAGUGGAGUCAGGACUUUGAAGUCCUCCAUUGGAUCUUCUCGGAAGAUGAGGGAAAUGAGAGAGUGUGGAGAGAGAUUUUGUAAGUCCGGUCUGGAAGUGGUCAUUGUUCAGAAUCCAGCCACGUGGGUACAUGGAACUGUAAGGCUAUUUCAACAUGGGAAACUGAAAUCGGGCAUAUCCCUGCGGAAGAAGCUGUCUCUUAGCGAAGAAUAAAACUGUGGACUGACCCCCACCCAUUUGCGAAGAAAGUACUGGGUCUUCAGCUUUCAUUGUUCAGCCGGUGGUCUUUGUGGACAACACCAGGGGCCCCUCCUGCUGAAGACUGUCUGGACUUCCUGAUUUUCACUCCUGUAUAAACCCCCUCCCCCAUUACUACCUUUGUCUCCUUGGGGAAAAAAAAUGUUUUUCACUUAAGCAAAAUAAUAACUACCCAGUAUUUGUUUCUGGAGUGAAAUUGUAAACUUCAUUGUACAUUCUUCCUGGCUUUGAUGCUUAUCGUGAAGAGUUCAGUGAAAAUAAAUUGUUUUUAUGAAAGCAGAG

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