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Homo sapiens (human) TNFRSF14 antisense RNA 1 (TNFRSF14-AS1) URS000075A9D9_9606

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TNFRSF14-AS1: TNFRSF14-AS1 is an immune-related long non-coding RNA (lncRNA) that has been identified as a prognostic marker in various cancers, including bladder cancer, breast cancer, and pancreatic adenocarcinoma [PMC8799921] [PMC9312832] [PMC7603345]. It is also associated with pyroptosis, a form of programmed cell death involved in immune responses [PMC8799921]. TNFRSF14-AS1 has been found to be significantly associated with T_stage and N_stage in bladder cancer patients [PMC8799921]. In breast cancer, TNFRSF14-AS1 is upregulated and associated with a longer recurrence-free survival time [PMC7603345]. Additionally, TNFRSF14-AS1 has been implicated in MHC-II antigen presentation and regulation of apoptosis and proliferation [PMC9845402] [PMC6987159]. It is part of a ceRNA network involving other lncRNAs (LINC00511, LINC01578, PVT1) and mRNAs (COL1A2, ITGA2) that are associated with poor overall survival in pancreatic adenocarcinoma patients [PMC9312832]. Furthermore, TNFRSF14-AS1 is part of pyroptosis-associated lncRNA signatures that can predict the prognosis of bladder cancer patients and divide them into low- and high-risk groups based on transcriptomic data from The Cancer Genome Atlas database [PMC8488148] [PMC9659888] [PMC9810632]. However, further confirmation is needed to establish the prognostic value of TNFRSF14-AS1 in breast cancer patients[PM7603345].

Genome locations

Gene Ontology annotations

Sequence

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AAAUGGGGGCUCACCAGCUGCCCGUGGACGGAGUGGGAGGAGGCCCCCAGUCUCCAGGAGGCUCCAUGCCUCAGGCUCAGACCGGCAGCUCGGGAACCCAGCUAGCAGGAUGAACUCCAGCAGAGGAACUCAGCGCCAUUGCUGCGGCUGUGGGCCAGAAGAGAAAGAGAAAGAGAAAGAGAAUCCGCCUCGGUGUGACAAGCUGUGCCUCAGAACCCGAGCAGCAGGAGAGUGGGCAGCAGGGGGUGUCUGGCAGCAGAGAGGGGCUCAGGCCUGCUGGGUGGAGCGGCGCUGGGGGACACAGGUGGGCCCUGCGGGAGGCAGGAGCUGUCCAGGCAAAGCCGAGGGGAAGGGCCGGUAUGAAGGAGGCGCCCGAUGGGAGGGGCGAGUUCUCCCCCUGCACCAUUCCAGUCCACUCCGGGUUUCCUGUAGAAGGGGGAGCCCCCCAAAGUCCAUCUGUGUUUCCCCACCUCACUCACACACUCAGGGACCCUCGGCUGCUCCCCGGGGCGCUGACUGACAUUUUUGCCGAAUAAAGGGGCCCUGUGGGUUUCCUGUUCCCAUCUCAGCUUCUGCUGAACAGGGUAAACUUCCCUUCCGAAUAAAACCACCAGAAUGCGGUCUGGCCAAUUUCAGUCAUAGACCCACCAGGCCUGUGUCCCUGCGUGAGGGGGUGGGAAAAGCCCAGAGUGCCCCUACCCGUCCCCUGGGAGGGGUGGAAGGGCAGCUCUUGCUCCCCCUGCAGAGACGCUGCGCGGACUGGGAAGGCUGCCAGCCUCGCCCGGUCUCCCUGUGGACCCUGCCCUGACCCCACCCCAGCUUCCUGGCUCCCUGCACCCCACUGGGCUUCCCUGCCCCACAGAGCCUGGUGGUAGGGAGACCUCCGGAUGGAGACAGCCCACAGUCCCGGAGCCCCAAGGCAGGCACCAGUGAGUCCCUCGUGACGGCCUCGCUCCCUGCAUCACAUGGAACCUCGUGACCCACGUGACGACGCCAGUGCCCCCGUGGCCCCUUCCUGCUGCUGGACGUGAUGCAGUCAAUGGAAGCCCAGGUCUGUCACGCACCGCCUGUGCUUGCCCAGAGCAGGUCCCAGUCACCCCCUCUGGCACCGCCUGCUGCACACCAGGAACCCCCACCUCCAGCAAGCCCAUCUGCCAGACGCCUGGCCCAGGACCGCCCCCUGCCCCUCGACUGCCCCCUGCCCCUCCUGGUCCUGACUUCAGCCAGGUGACCCCCUCCAGGGUCCAGCCCUGGCCCCUGGGGGACUCAGUGGCAUCUGGUGGAAAGGACCUUGGGGAUUGCGCCCACCCUCACCUGCAGGAGAGUUGGCAGGGUGGCCAGCCACAGGAAUCUGUGGCAGGAGCCCGGGGACCUGCACCCCAACUAGAAAGUGUGCAGCCCUGCAGGCCGGCCCUGGAGAGGGAGCAGGCAGGGGUGAAGUUAGGCCGGCUGUGGUGUGCGACACCGUCCUGUGGGGCCAAGCGUCCCGAGCUCCAGAGGCAGGUGCACUCCUGGCCAGCAUCCAGGGUGGACGAGCCCAGACCCCAAUACUCUGAGGCAGGGUGGGGGACCAGGUGGCACCCAGUGGAGGAAAAGCCCCCAAGAGACACGCAGGAGCAUGGACUCCCACCCCACAGCUGGAGCCUGGGAGAGGAGCCCCAUCUGCUGUUUCCCUGGUGCACUCACAUCCUGGCCCUCAGCGCCCCCUGCCAGGAAUGUCCCCCACAUGCAGAGCCAUGUGGGUCUUGCAAGGAAGAAGAAGGGGGCCCCUUGCAUCCUCCACUCCCGGGGGCCCCAGGAGGGCAUGGGGGCUCCAGGGUGCAGGGACAGCACGUUCCCUCACCAACUCCCCAAGAACGCCCAACCUCCAAGAGCAGACACAGCGCCUACACCUGCCGGUACGGGGCUCCAACCCCACUCUCUCAGAUACGUCCUCCAGAGUCGUCUCAUCCACCCCACCCUGGGGAGGAGGGAAACUGAGGCAUGGCAAGAGACAAGACUAACACAGCGUGGGCUCUCCCGGCACCAGCACCGCCAGGCCCUGUGCAGGACCCCAGGGUCAUCAGGAAGGAAAUGAGGCAGCCCAAGGAGGCGGGAGACGGGGCCCUACCCAGCACCCAGCCAUCUGCAUUGACACGGCUGCCCGCAGGAUAUCACUGCCCCCAUCCCGGGGCCCACCAUUACCAGCAGGGAGAGGGAGGCAGAGGGAAGCUGGGGUCCACCGCUGGUGAGCGGGGAGGGGACGGGACACAGAACCGGCCGUGGCCCACCCCGAGACGGAGGCGCAGACACCAGGCCCGUUCUGUGCUCUGGAGGCUUUGGGCAGCUGUCAGGCUAGUGGACGGUGUGCAGAGCAGAUGGAGGCGUGAGGAGGCGGCUCCGGGGUCACCUAGGUUCAGCAGGGACAGAGCUCAGGGGGAAGGCACCUCCCGUCCUGGUUCAAUACAUGGACCCCUGACCCUGGGAAAGGGACUGAGCCAGGGGAGGCCUCAGGUCACUGCACCAUGAAGUUGUGGGGAGCUGCGGGGGCCUCUGGGCUCCGAGCUGGGCAGGCACAGCGUGGGGACCACGUGCCGAGGGGAAGAAGCGUGCCAGGGUGGACGUCUCAGUGCACACGCAGGAACAUGCAACGGCUGAGCCAGCCCAGAGAGGCAGCGGAGCGUGUGCGGGGCGGCCGGCGGAGGAGCAGCAGGAUCCCAGGCGGGAGCGCACGGCCUUUUCGGAGGCAGGUUCCAGGACAAUACUAAGCGUUUACAUCAUUGCACUAUUUGAUCCAGGAGGUCCCACUGUGGCGUUUCAUCGAUAAACGCACAUGCGAGGUGGAGGGUGGCUGGUGUGGAAUGUGCCCGGCAGCCUUCAUAGCAAAGGAGAAUUCUAGAACCAACCGAAGUGCCCCUCUGAAGGGAGCUGGUCCCGUCCGUUCCAGCCGCCGUGGAGUAACACAGCCAGCAGUUUCCCUCCUGCCACGAAAGCUCGAGACUGAAACUCAGGAUGAACUGUUUUCAGCCCGGGUCACCCCAGCCCUGGGGUGGAGGCCCAUUGAGGAUGGCCGAGCAGGGGCGGGCAUCCAGGCAGGUCCAGCAGUCCUGGCGGGCUGAGGAGAAGGAGGUCAGUGCUCAGGGAGACAUCCGCAGAGGGACCUGGCAGGCAGAGCUCCAGAAGGGAGGGAACUGCACAGACAGAAAGCUCCAGAAGGCUGCCUGAGGGCCUCUGAGGCCUCCGGAGUCAGGCGCCAUGGAUGUGGAAGGUGGACUCUUCAGCAUGGAUGGGACCCUAGGGGGCUGUGGACCCCCGGCCCCUGGGACUCACAGGUGGGAGACAGGAGUUCCAACCGCCAGGGGGAGAGUCCUGGAGGAUCCUGGGCUGUUGGCAGCCACCCAGCAGGGCCCGUCCUGGGAGUGGGGCUGGACUCUUCCUGCAGGAAAGGCUGGGCUGGACCUGCUCUGAGAGGCUUCAGAACCAGCCACACGAAGACCAAAGUGAAGAGCAAGGAGCUGAACUCCACGCAGAACACAGCGCAGCGUCCUUUAAAGGAAGGCCAAAAACAACCCAACAAAAAUGCCAGGUGAUCAAAGCGGUCACAGCACAAUGUCCACAUCCAACGAGAAAUUGCUACUACGUCCAGACGCAGGGAAAGGUGGCCGUGGGAACGUGAGUCAGCAGCAACAGGCCCAGAAGGGCAGCCACGGUGGACUUGUCAGACGUGGACCCUGAAAUGACAAUCACAGCAUGAUUUCAGGCAGGAGCCUGAAAUGGUACAGCUUUGGACAUCGGUUUGGCAAAUUCUUUUAGAGAGAAACACACACCUUCCCUAGGACCCAGCAACUCCACUCCUAAUAACCAAGUGAAAUGGAAGGAGUUGUCCUCAGCAAAACGUGUGUGCGGAAGUUCACAGUCACUUUCUCGGUGAUAACCAAGAGCUGGAAACCACUGCAACACCCACCAGCAGGUGAACGGAUUAACACACUGGGCUAGGGCCACACAAUGAGAUGCUCCGUGGCAACACAAAAUGAACCGUGGACACACACUGCACGGCGGAUGAAUAUGCAGACAUCAGGCCACGUGAAGGGAGCCAGGCCCCGAGGCGCCACGCUUUGUGAUUCAGGGUGGUCCCUCUGCGCCCAAGACCCGGCUGCCUCCUCCUCUUCCUGGCUGCAGGGAGUGCUUGUGUCUGAAGAACGCCAGGCUGGUGUCCCCAGAGGGCGGCUGGAGGGGCUCAGAAACCAUUUUCACCUUCUGUCUCCUCCAUGUCUGCACUGUUUGGGAAAGAAAGCACGCAGCCAAAGAGCGCAAAGAGGCUCAGAGGAGGCCCGGGUGCCCUGGAGAGACGCUGCGUCCUGACGACACAGCAUCCCUGUCCCGCAGCGGAGAUUUCCCAGAUGAAGGAUUCCCCGGCGGGAGACAGGGCCCUGCACACAGGUCCUCUGCCACGCUGCUCACCAUGCCUGUGUGUUAUCUCCCCAUGAAAAGUCACCUAGGCCGAGCAUGGUGGCUCACGCCUGUAAUCCCAGCACUUUGGGAGGUGGAGGCGUGCGGAUCAUCUGAGAUCAGGAGUUUGAGACCAUCCUGAGUAACAUGGUGAAACCCCGUCUCUAGGAAGAAUACAAAAAUUAACUGGG

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