v24

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Homo sapiens (human) long intergenic non-protein coding RNA 1549 (LINC01549) URS000075A936_9606

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LINC01549: LINC01549 is a long intergenic non-protein-coding RNA (lncRNA) that has been studied in various contexts. In a study on patients with cirrhosis, higher expression of LINC01549 was found to predict better overall survival (OS) [PMC7568908]. Another study identified LINC01549 as one of the lncRNAs significantly associated with OS and disease-free survival (DFS) in patients with hepatocellular carcinoma (HCC) [PMC6095106]. The expression of LINC01549 was negatively correlated with OS and DFS, indicating that higher expression levels were associated with better prognoses [PMC6095106]. Additionally, the study found a significant positive correlation between the expression levels of LINC01549 and OS/DFS [PMC6095106]. In another investigation, LINC01549 was one of the lncRNAs that showed differential expression between different clusters in HCC patients [PMC9273977]. Furthermore, it was found to be negatively correlated with the expression level of PD-L1 in HCC [PMC9273977]. Additionally, a polymorphism between CXADR and LINC01549 gene called rs6517774 (A>G) has been identified [PMC7464158]. Overall, these studies highlight the potential prognostic value and biological significance of LINC01549 in various diseases. However, further research is needed to fully understand its functions and mechanisms in HCC biology [PMC7377850][PMC7464158][PMC7568908][PMC6095106][PMC6535863][ PMC7377850][ PMC9273977][ PMC9178207] .

Genome locations

Gene Ontology annotations

Sequence

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GCUGUUGAGACUCCAGGGGUGUUCGGGGCUGGGAGCCUGCUGAGUGUUCCCUGUUCCCACCUCCAAUCUGCUCCAUCCUCCAGCUGCAUUUCAUUCCGGAUCUACCAGCAGGAUCCAACUUUACUACUGUCAUGGAGGGAAUUACAGUAAUUCUACCAACUUUUGAGGCAACCUUCUUCUGACACUGUGUGAAACAGACUGAAAAGACUCUAAAGAUGGAGAGAGCUCAAUGCUUGAGAAAAGGAAUUCUGUCCUUUGAAAGGUCUCUAGAACAAAGGAGUCUUAUUCUGUCACCUAGGCUGGAGUACAGUGGUGCAAUCACAGCUCACUGCAGCCUCGAUCUCCUGGACUCAACUAAUCCUCCUGCCUCAGCCUUCUGGGUAGUUGAGACUACAGAUACAGAAGAUGAGAGAGAGAAAAAGAGAGAAAUUACAGAGUGACGGAGAAGGCAGACAUCAUGCAACAUGCUCAAGGGCUAUUCAUUUUAAGCUGAAACAUACAUGUGUAGAAAGCAUCCUUGUACUUAUAAUCCCAAUGACUAUGAAGAAAAAUAAUUUAGCCAAAUAGUUCCUAGAACAGGAAAAAUAAGGAAUUAUAUUUUGAGAUAAGAAGUUAAGCUCUAGUAUAACAAUGAUAUGGGUCAAAGAAAAAUGAAAACAAAUUUUAAAAACGUUGCAACAUGAAUAAAAGUUUCACCAAAUCGGGAGUCUAUUAUAAAAAAAAAAAAAAA

Taxonomic tree

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Publications