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Homo sapiens (human) FAM170B antisense RNA 1 (FAM170B-AS1) URS000075A8FF_9606

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FAM170B-AS1: FAM170B-AS1 is a non-coding RNA gene that has been implicated in various biological processes and diseases [PMC6038674]. It has been identified as a candidate gene that may disrupt hepatocellular carcinoma (HCC) homeostasis and affect cancer cell proliferation [PMC6038674]. In a study, FAM170B-AS1 was found to have potential in discriminating between TP (tumor) and NT (non-tumor) samples, with an AUC value of 0.917 [PMC6038674]. Additionally, FAM170B-AS1 was negatively correlated with the expression of GRIK2, which is upregulated in TP samples of HCC [PMC6038674]. In the context of diabetic foot ulcers (DFU), FAM170B-AS1 was identified as a key regulator in DFU progression by co-expressing with 52 differentially expressed genes (DEGs) [PMC6764308]. Furthermore, FAM170B-AS1 has been newly identified as one of the loci associated with susceptibility to coronary artery disease (CAD), along with other genes and chromosomal regions [PMC6201041]. However, it is worth noting that FAM170B was used instead of FAM170B-AS1 in the analysis for CAD susceptibility [PMC6201041]. Lastly, five single nucleotide polymorphisms (SNPs) in TNS3, BTRC, STIM1, TRPM1, and FAM170B-AS1 were not found to be associated with intermediate phenotypes related to CAD [PMC6201041].

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Gene Ontology annotations

Sequence

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AAAGCAUUACAUGUUAUUCUUAACACCUGCCACUUCUCUCUUCCCACCUCUAUCUGCCUUAUUGAACUUCAUCUUUCCUUCAUUCUCUUCAACUUCCACUUCUUCUUGUAUGGUCCUGUUGAUGCCAUCUUGUUUCCGUCCCCAGACUCAUCAUCUUUACCCUCUGUCAACUGAGUUCCCACCCUGGUUCUCUCUCAAGAUCUUCCUCUCAUAGCUUUCACCCUUGGUAAACAAUGAGGACACAUCUCAAAAAGAAUGAUGUAAUUUAAUUGCCUUGAGUUGGCUGGGCCAUCAUCUAUUAUAAAGUGCUCUUAAAAUUAAAGCUAAUUUAAUUCUGAAGAACUAAGGAUUAAGAAGUUAAGAGCUGGGGUUCUUACAAUAUGGCUUGCAGACUACAAGUGUGAACUGAGGAGGUCCCCAAAGUCACUUCUUACUAAGGACUCUGGGAGUUGCCUCUUCCUUCUCCAUUUGCACAAACCACGCUUCAGCCUCAAUCAGCCUGAUAAAAUGUUCACCUGCCAUCUCUCUGCUCUGCAACACGCUGGCACUUCACUCAUUUCCUCCAACAAGCUUCUUACCACUUCCCUCUGUGGCUAAUCUCUUCCCACCCUUGGUCAGUCUCAUCAACUCUAUUCCUUUGAAUCCCAAAUACUAAACAGUUCAGAUAGGUGAUGGAUUGAAAAUAAUCCCAAUAUUCCACAAGCAACAUCAACAUCCCCCACACACCCAGCACCGAGGAAUACCCUCCUCUCUAGAAUGUGAGGCCACUGUGUGGAGGAAGACACCACGGUGCUCUACUGAGCCAUGAAAGUCACGCCUGACCUAAACAGAAGACUACGUCCCCUGGCUAAAAGAGGAAAUAGUUGAAAGCGGUGUAAAUGGCUCUUAUCUGAACCACAAUGAAUUCACAUAUUCAAGUUGGCUUCUUCGGAAAUUUCAGGCCACAAAUGGCAGUGAUGCGACCAGGAGCAGUAACACGAUUACAAGUCGCAAUUUAGGAAGGGUGCUCCAUCAUCAUUUCAUGAUUCUCACUACAGCCCAGACAGGUGGGCAGAGCAGUGUUCUUUCCCCUUUAAUGAAUGAAGAAGCUGAGCCUCAAACAGAUGAGGGGGCUUCCUGGGUUCACAGAGCUCUAAAGGGCUGAGCUGUAGAUCCACGGCCACCAUGAUGAGCUAAGAGUUUCUGGAUUCAGUGCCUGCUGUUGCUCCUGGAGAUUUGUAUCCUGAUUGAAGGCUGGUUCCAUAUCUGUUCACCCAGUGCCACUUCCAUCCGGACAGAAGGAACCCAGGUCAAGGCUGACAGGAGGAGCAGGAGCCGUCAAUGAGAGCAGACCUCAGAAGCCAACGGAGGUGAGAAGAGCACCAUCCACAGCCCCAUCCUCUGAAUGCUGUGGGAAGAAGUCCACAAAAUACCACCCCUUGGAGUCAGUCAGUAGUAGAGCCCUUGCUGCUGGCUGCAAAUACCCCAUCAGAACAUGUUUGGGGUGAUUCUUGGACCUGGUUUCAAUUUCUUUUCUGCCAGUCAGCAGUUGUGCUUGACUCACAAUUUGUUGCCAUCUCUUGAAUUAAACUCAGGAAACAGGAUAAAGAUCAGAACCACAUUGUAAAAGCUUCCUUAUGGUUCAUUUUUUGCUGAGAUAAAUAAUGAGCAGCUCUGAUCCAUGUCUCUGGAGAGCUCAGAGCACACUACCAGGAGCUCCUAGCCACAGGGUGAGCACAGGUGGCUGGUGUUCUCUUGAUGAGGAAAGACAGCAGUGUCCAAUCUACCCUGCCUUACACGGAGCCCCAGGUGCUCUCCCGGACUGUGUUGCUACCUAAAGCACAUGGCAAUUGCAUGAUGCUAACCAGAGCAGCCCCUCACUCAUUAGAAACAUCUGCUUUGCAUUAUUUACACAGGCAAAGUUUUCCUUUUUACUGAGCCUACCCAGUUCAAACUUAAGUGGGAUUUGCCAGCUAUCUGGCUAAUUUUAUGAGCAAUAAUAAAGAUUGGUGAACACUUGGAAAAAAAAAAAAA

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