Homo sapiens (human) long intergenic non-protein coding RNA 324 (LINC00324)

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Homo sapiens (human) long intergenic non-protein coding RNA 324 (LINC00324) URS000075A69B_9606

2,115 nucleotides
4 databases (GeneCards, HGNC, MalaCards, RefSeq)
Found in 0 other species
137 publications

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LINC00324: LINC00324 is a long non-coding RNA (lncRNA) that has been studied in breast cancer [PMC7202516]. In a study involving 960 breast cancer patients, data from TCGA and GEO databases were collected and analyzed to determine the expression of LINC00324 and its relative prognosis in breast cancer [PMC7202516]. LINC00324 has also been found to play a role in other types of cancer [PMC8882835]. In gastric cancer, it was found that LINC00324 can enhance the stability of FAM83B and WDR66 messenger RNA by binding to HuR, a protein involved in RNA stability [PMC8882835]. This interaction promotes cell proliferation [PMC8882835]. Similarly, in osteosarcoma, LINC00324 was found to enhance the stability of WDR66 messenger RNA through binding to HuR, leading to increased cell migration [PMC8882835]. These findings suggest that LINC00324 may have oncogenic properties and contribute to tumor progression in various types of cancer [PMC8882835]. Further research is needed to fully understand the mechanisms by which LINC00324 functions and its potential as a therapeutic target [PMC8882835].

Genome locations

Gene Ontology annotations

Sequence

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AUGGGUUGGGCAUUAGGAACGGCCUGGCCCCACAAAUCACACAACUGGGGUGUAGAACAAAAUGGUUCCACAGAUGACACCAGGCUGGUCCAGGGCCGAUGCAGGCCAGAACCCCGCUGGGAGGACUCCCCAGAACAGGCACUGAGCUGAGGAAAGGCAGGACACGUGGUCUGCUACCGACCCCACCAGAUCUUGCUGGGACUCUGGGCAGCUCCGGAGUAAGAGCAGCAUGCUCUGCAACGAAGAGCUAGGUCCAAGGACCGCAGGCGGAGGCAGGAAGUGUCAAGAUCCCAGGUUACGGAAUGGCACCAAGUCGGUAACCAAAGGAAGCAACAACCCGGGUGUUCAAGGCAGUCGUGCAAGGCGGCGCGGGGGCGAGGCCGAGGCCACUCCCUCCCACUUCCUUGACGCUAUUUCCUGGGAGGAGCCGGAGCUCGCGGCCCGGAGCCAAGAGAUUCCCAGCCCAGUGCUCCAAAAUACUCGGCCUGGGGGAGGCUGGUCCGUGAGCGUGCGCCCGGACCGUUCCGCCAUGCAUAGUGGACCCAGCACUACAGCAAGCCUGGCACGACCUCUAAGGCGGUUCGCGGCAACGUCCGCACGUCGGCUCGUUGGUCUAGGGGUAUGAUUCUCGCUUCGGGUGCGAGAGGUCCCGGGUUCAAAUCCCGGACGAGCCCUCCUUUACCUUUUACUGAGACAAGAGUGUCUUCAAGGAAUAGGUUACCUGACCAGCGCUGCAGGAGGCUUGACUGUAAGUCAUCAAUGUACAGUAAGCUCUUUUGUGGCACCGCGGUAGCAGAAAGCAUCUCAAUCCCCAGACCCGCCUGGCAUGUCAGGAAGAGACGAGGCACGCCCAGACUUGGGCAGGUCCCUCCCUUUCUGCUUCCUGACUUCCUUCCUGGUGUCUCAACUCGGCCACCACAGCCUGGUUUCGCUUUGAUUGACACGCGUCAAUCUAUAGUUGUGGAUGACAGUGUUCGGGAGAGCCCAGGAACUGUCAAAACUUGGUUCUCUGCAGUCCUGAAGGCACUCUGUCUCUUUCGGUCACUCCAUCUGACGAUUGGUGCCUGAAAUACACCUACGGUUUCUGGUCAGCGUUUAUCAGUGGUUGGAAGAACAGAACCCCUAGGAACCCUGCUGUCAGCACGCAGAGUGUAAAGUCUCAGAUCAAGGAUUCGGAGAAAGGUCUCUACAGGUCCCUCCUCGUUAGUAUAGUGGUUGGUUGGGAUGAGUCGGGUUGGACCCGUGCGGAUCCAGGAAAACAGCGAUCGAGGUAAAAGUAAUGGCUGCCGUCGUCUGCCCAGCGCGCAAUUGUGAGUGACCUUCACCGCUAGCGCGCGCCACCCACCCCACAUGAACCUGUAGGGUUAUGCCCAGUCUACAGACGAGGAAACCAAGAUCCAGGGAAGCUGAGUCACCGGCAGAGCUGGGAUUACGUCUAAGAUUUGUCCAGGGGGCGAGAACUGCAGCGACACCAUGAUUUAUCAUCUCCAGAAAACAAAAAAAAAGGCCUAGACACAUAAAAAUGGCUUCUCUGUAGAGUGAGCUCAACGAGCUCAAUGUGAUUCCAGUUAAGGAAUUGGGCCUUAAGCCAAAUGCGCCUAAACGCAACUUGCCUCUCUAUUAUUUAUCCAGAGGAUGAAUUUAAUUCCUACGUACAUGCGCCCACAUCUCGUCAGCUGGUGCCUCAGAGAAAUGCGCUGACAAAUCUUAAAGGUGGGGCUUCAUGACAAAAGUCCGCCCGUUAUUGCUGCUCAACAGACCCAUCAAGUCACGCUGUUGGACAGGCCUCGUGGCGCAACGGUAGCGCGUCUGACUCCAGAUCAGAAGGUUGCGUGUUCAAAUCACGUCGGGGUCAAACAAAACAUUGUUUUCCCUAAUCAAAUAGACCUACGGUGACAUUUUUCAGGAUAGGAAAAAAAAAAAGCCUCCUCAGUAGAAGGAUAGGAGGGGAAUGAGACAAAUAUGAACGUUAUUCAGAAGUUGGGUGCAGACUUUCAACAUUAUGUGAUAUAUCCCUGUGGCAAAACUGCGCAUGUAUCCCUAAGGUCUAUAAAAGUAAAAAUAAAUUUAAAAAUAAAAAAAUUCCCUGUUGUAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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2D structure

Publications