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hsa-mir-4287: Hsa-mir-4287 is a down-regulated miRNA that has been identified in several studies. In a combined analysis of GSE46823 and GSE83292 datasets, hsa-mir-4287 was found to be down-regulated, along with hsa-miR-1323, hsa-miR-711, and hsa-miR-650 [PMC9812810]. Another study listed hsa-mir-4287 as one of the miRNAs that linked several genes [PMC9480065]. In placenta tissues supporting larger twins of sIUGR, hsa-mir-4287 was found to be down-regulated [PMC5865797]. Furthermore, in a study comparing girls and boys, the expression of hsa-mir-4287 was inversely correlated with the expression of DDX3Y and CDK16 in girls [PMC7993149]. Specifically, DDX3Y was down-regulated in girls while CDK16 was upregulated. Hsa-mir-4287 had the highest opposite deregulation compared to DDX3Y in girls compared with boys [PMC7993149]. Overall, these studies suggest that hsa-mir-4287 is involved in various biological processes and may play a role in different conditions. However, further research is needed to fully understand its functions and mechanisms of action.
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