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MIR4519: MIR4519 is a microRNA that is mapped to a gene encoding noncoding RNAs (ncRNAs) [PMC5545731]. It is involved in tumorigenicity by interacting with its direct target N-ethylmaleimide-sensitive factor (NSF) and associated receptor SNARE [PMC6712160]. The expression of MIR4519 is associated with high risk, as high expression of MIR600HG and low expression of MIR4519, POLD3, and MTA1 were found to be correlated with high risk [PMC6712160]. The Kaplan-Meier plots in Figure 3 show the association between the expression of MIR600HG, MIR4519, POLD3, and MTA1 with survival [PMC6712160]. Additionally, the on-treatment differentially expressed genes (DEGs) include MAGEA1, MAGEA2, KLF10, and MIR4519 [PMC7673759].
References:
- [PMC5545731]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545731/
- [PMC6712160]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712160/
- [PMC7673759]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673759/
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