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gga-mir-200b: Gga-mir-200b is a microRNA that is significantly differentially expressed in various studies. In one study, it was found to be up-regulated 2.2-fold in the fat line [PMC4326283]. Another study used Taqman probes to detect gga-mir-200b, indicating its importance in quantification [PMC7477046]. Integrative miRNA target prediction and network analysis revealed that gga-mir-200b targets the RECK gene, which is related to skeletal muscle development in chickens [PMC7999090]. Additionally, gga-mir-200b was predicted to target both SREBP-1c and HMGCR genes [PMC3436634]. It belongs to the miRNA gene family of miR-8 and is located in the same miRNA cluster as gga-miR-200a and gga-miR-429 [PMC3436634]. In a study on leptin-treated chickens, gga-mir-200b was found to be significantly up-regulated in the liver [PMC3436634]. Overall, these findings highlight the importance of gga-mir-200b in various biological processes and its potential as a therapeutic target.
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