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MIR499A: In our study, we failed to observe an association of the polymorphism in the rs3746444 polymorphism of MIR499A and the miR-499a expression [1]. MIR499A expression was also examined in Ad-HBV or Ad-GFP infected HepG2 cells [2]. In addition, we explored the target gene of MIR499A to disclose the underlying mechanism of MIR499A functions in HCC [2].
References:
1. Zhang, Y., Zhang, Y., Li, X., Zhang, X., Liang, H., Liang, W., ... & Wang, Y. (2021). The association between polymorphisms in microRNA genes and hepatocellular carcinoma risk: a meta-analysis. BMC cancer, 21(1), 1-12. [PMC8514969]
2. Wang, Y., Tohme, S., & Gao, Z. (2014). MicroRNA: a new therapeutic target for human hepatocellular carcinoma. Gastroenterology research and practice 2014. [PMC4207808]
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