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hsa-mir-4433b: Hsa-mir-4433b is a miRNA precursor that gives rise to the miRNAs hsa-mir-4433b-3p and hsa-mir-4433b-5p [PMC4486185]. In a study, several critical miRNAs, including hsa-mir-4433b, were identified through screening [PMC7505395]. The test value of hsa-mir-4433b with more 0 value may lead to a high P value [PMC7505395]. The expression patterns of eight specific miRNAs, including hsa-mir-4433b, were verified in test data from PC samples and control samples [PMC7505395]. Hsa-mir-99b, hsa-mir-4433b, and hsa-mir28 were among the 10 most highly expressed miRNAs in PC storage on the 2nd day but were replaced by other miRNAs on the 4th day [PMC4486185]. Hsa-miR221, HSA-MIR22, and HSA-MIR423 were among the most highly expressed miRNAs in PC storage but have not been previously associated with platelet physiology [PMC4486185].
References:
[PMC4486185] - Kirschbaum NE et al. (2015) Expression profile of platelet microRNAs associated with the 5-day apheresis process. Transfusion 55(6):1152-1163.
[PMC7505395] - Zhang Y et al. (2020) Identification of key genes associated with platelet transfusion refractoriness in patients with acute leukemia. Medicine (Baltimore) 99(28):e21099.
[PMC4486185] - Kirschbaum NE et al. (2015) Expression profile of platelet microRNAs associated with the 5-day apheresis process. Transfusion 55(6):1152-1163.
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