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SNORA70J: SNORA70J is a small nucleolar RNA (snoRNA) that has been studied in the context of ovarian cancer (OC) prognosis prediction. A signature based on nine snoRNAs, including SNORA70J, has been developed to predict the prognosis of OC patients [PMC10001105]. The expression abundance of SNORA70J, as well as its host gene RPSAP71, is found to be very low in ovarian cancer tissues [PMC9119353]. The expression levels of SNORA70J and other snoRNAs (SNORA11B, SNORA36C, SNORA58, SNORA75B, SNORD3C, SNORD89, and SNORD105B) were analyzed using qRT-PCR in clinical tissues and were found to be downregulated in tumor tissues compared to their paired normal tissues [PMC9119353]. Primers for amplifying the expression levels of snoRNAs including SNORA70J were synthesized using a probe method [PMC9119353]. The nine snoRNA signature that includes SNORA70J has been identified as a potential prognostic and therapeutic target for ovarian cancer [PMC10050728].
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