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SNORA47: SNORA47 is a type of small nucleolar RNA that has been implicated in the progression of non-small cell lung cancer (NSCLC) [PMC5838311]. Patients with high expression of SNORA47 have been found to have shorter overall survival rates and higher recurrence rates compared to those with low expression [PMC5838311]. In a study using A549 cells, it was observed that these cells were more susceptible to treatment with SNORA47 shRNA [PMC8017274]. This finding led to the selection of A549 cells for further analysis [PMC8017274]. The study also found that knockdown of SNORA47 could inhibit the progression of NSCLC by inhibiting the epithelial-mesenchymal transition (EMT) process and the PI3K/Akt signaling pathway [PMC8017274]. These results suggest that SNORA47 plays a role in promoting NSCLC progression and could be a potential therapeutic target for this type of cancer [PMC8017274].
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