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Homo sapiens (human) small nucleolar RNA, C/D box 3B-1 secondary structure diagram

Homo sapiens (human) small nucleolar RNA, C/D box 3B-1 URS0000720EFA_9606

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SNORD3B-1: SNORD3B-1 is a small nucleolar RNA (snoRNA) that has been implicated in various biological processes and diseases. It has been identified as a non-coding driver element in cancer, including prostate cancer and liver cancer [PMC9477733] [PMC8855550]. SNORD3B-1 has also been found to be upregulated in CD14+ monocytes cells and NK cells, both in individuals of White and Asian descent [PMC8060402]. In addition, SNORD3B-1 is dysregulated in age-related immune dysfunction and Alzheimer's disease [PMC9359077]. It is also part of a panel of genes associated with dilated cardiomyopathy [PMC8701745]. SNORD3B-1 has been identified as a potential biomarker for liver cancer, with high abundance in plasma exosomal RNA-sequence datasets [PMC7681086]. Furthermore, SNORD3B-1 is included in a 3-RNA panel (along with circ-0080695 and miR-122) that shows high accuracy for classifying liver cancer patients from healthy donors [PMC7681086]. The structure profile of SNORD3B-1 has been collected from the Rfam database, indicating its potential functional significance [PMC7681086]. Overall, SNORD3B-1 plays a role in various diseases and biological processes, making it an important target for further research.

Genome locations

Gene Ontology annotations

Sequence

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AAGACUAUACUUUCAGGGAUCAUUUCUAUAGUGUGUUACUAGAGAAGUUUCUCUGAACGUGUAGAGCACCGAAAACCCCGAGGAAGAGAGGUAGCGUUUUCUCCUGAGCGUGAAGCCGGCUUUCUGGCGUUGCUUGGCUGCAACUGCCGUCAGCCAUUGAUGAUCGUUCUUCUCUCCGUAUUGGGGAGUGAGAGGGAGAGAACGCGGUCUGAGUGGUU

Taxonomic tree

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2D structure Publications