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SNORA70B: SNORA70B is a small nucleolar RNA (snoRNA) that has been identified as part of a snoRNA signature for the diagnosis and prognosis prediction of renal clear cell carcinoma (ccRCC) [PMC10050728]. In a study conducted on a Turkish dementia cohort, it was found that SNORA70B, along with its host gene USP34, may play significant roles in ccRCC tumorigenesis through the Wnt signaling pathway [PMC7011154]. Additionally, SNORA70B was found to be positively related to CTNNB1 and USP34 was positively related to CTNNB1, MYC, TCF4, and TCF7L2 [PMC7011154]. The expression levels of SNORA70B were found to be positively correlated with its copy number variations in ccRCC [PMC7011154]. Furthermore, previous studies have shown that SNORA70B is abnormally expressed in ccRCC and is associated with poor survival outcomes for patients [PMC7812721] [PMC8658237]. In conclusion, SNORA70B is an important snoRNA involved in the development of ccRCC and may have potential diagnostic and prognostic value for patients with this type of cancer.
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