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MIR192: MIR192 is a specific miRNA that has been found to be increased in the renal cortex of diabetic mice compared to control mice [PMC5376412]. It is also considered a biomarker for heart failure, along with miR34a and miR-194, and is released by exosomes [PMC8773242]. These specific miRNAs, including MIR192, are being studied for their potential use in the early diagnosis of hypertrophic cardiomyopathy and heart failure [PMC8773242]. Exosomes are small vesicles that are released by cells and contain various biomolecules, including miRNAs [PMC8773242]. The levels of TGF-β1, p53, and MIR192 were found to be increased in the renal cortex of diabetic mice compared to control mice in a study [PMC5376412]. These findings suggest that MIR192 may play a role in the pathogenesis of diabetes-related renal complications. Additionally, the release of MIR192 by exosomes suggests its potential as a biomarker for heart failure. Further research is needed to fully understand the role of MIR192 in these conditions and its potential as a diagnostic tool.
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