SNORD111: SNORD111 is a small nucleolar RNA (snoRNA) that has been found to be up-regulated in FFPE tissues [PMC7812721]. It is one of the candidates that were further validated in a cohort of ccRCC patients and healthy donors [PMC7812721]. SNORD111 is part of a group of snoRNAs that give rise to over 90% of the processed fragments [PMC4914119]. It has been found to interact with other snoRNAs, such as snord16, snord68, and snord94, and may influence the modification of rRNA and U6 snRNA [PMC6176948]. SNORD111 has also been investigated as a potential diagnostic biomarker for NSCLC. It was found to be significantly upregulated in NSCLC patients compared to healthy donors [PMC9701848]. SNORD111 was stable and consistently measurable in plasma samples, indicating its potential as a non-invasive diagnostic marker for NSCLC [PMC9701848]. In addition, SNORD111 was found to be significantly increased in NSCLC patients compared to healthy donors when validated using TCGA data [PMC9701848]. However, the specific role and clinical significance of SNORD111 in tumors are still not well understood due to limited studies on this snoRNA [PMC9701848].\nReferences:\n- Additional file 2: Fig. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812721/figure/add2-10-20/)\n- PMC7812721 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812721/)\n- PMC4914119 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914119/)\n- PMC4282444 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282444/)\n- PMC6176948 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176948/)\n- PMC9701848 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701848/)\n- PMC9644097 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644097/)\n- PMC7720690 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720690/)\n- PMC6124571 (https://www.ncbi.nlm.nih.gov/pmc/articles/PM